Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 11:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5021
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

Filter healthy volunteer studies

These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

Reset healthy volunteer filters
Clear filters
Showing 637–648 of 5,021 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Recruiting Phase 2 Interventional Accepts healthy volunteers

JAK Signaling in Depression and Cognition in Male Football Players

NCT07608796
Conditions
Depressive Symptoms, Cognitive Symptom
Interventions
Baricitinib
Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 55 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Microbiome Analysis
Interventions
Exogenous ketone ester
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Latinx Children and Surgery

NCT06020677
Conditions
Pain, Postoperative, Pain, Acute
Interventions
L-WebTIPS
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
2 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Orange, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Lower Body Negative Pressure to Validate Physiological Monitors

NCT07840144
Conditions
Physiological Stress
Interventions
Lower Body Negative Pressure with Noninvasive Physiological Monitoring
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Recruiting Not applicable Interventional Accepts healthy volunteers

Benefits of Nicotinamide Riboside Upon Cognition and Sleep

NCT05500170
Conditions
Cognitive Impairment, Sleep Quality
Interventions
Nicotinamide riboside, Placebo
Dietary Supplement
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Buffalo, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Anchoring and Postural Stability

NCT07837778
Conditions
Healthy Adult Participants
Interventions
Normal Stance, Inward Anchoring, Outward Anchoring
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Recruiting No phase listed Observational Accepts healthy volunteers

Pennington Center Longitudinal Study (PCLS)

NCT00959270
Conditions
Health Behaviors, Development of Health Problems
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
30,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2050
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Insomnia and Insulin Resistance

NCT07333586
Conditions
Insomnia, Insulin Resistance
Interventions
CBT-I, sleep hygiene
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Alzheimer's Disease, Healthy Participants
Interventions
BMS-986446
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 80 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
6
States / cities
Anaheim, California • Bradenton, Florida • Daytona Beach, Florida + 3 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

NCT06888024
Conditions
May-Thurner Syndrome, Iliac Venous Compression
Interventions
non-contrast enhanced abdomen and pelvis MRI
Procedure
Lead sponsor
Ningcheng Peter Li
Other
Eligibility
18 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Worcester, Massachusetts
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

HA35 Acute Alcohol Study

NCT05025865
Conditions
Healthy Controls
Interventions
Sodium Hyaluronate, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio