Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

The live registry is temporarily unavailable. These stored records may be incomplete or out of date. Check the official record for current status and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5020
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

Filter healthy volunteer studies

These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

Reset healthy volunteer filters
Clear filters
Showing 961–972 of 5,020 healthy volunteer trials.
Indexed local directory records.

Stored official records

Recruiting Not applicable Interventional Accepts healthy volunteers

Intermittent Cottonseed Oil Consumption

NCT07246408
Conditions
Dyslipidemia, Nutrition, Healthy, Overweight and Obesity
Interventions
CSO-20, CSO-30, Control
Other
Lead sponsor
University of Georgia
Other
Eligibility
25 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Influenza Prevention, Pandemic Influenza Prevention
Interventions
ALFQ, VRC-FLUMOS0122-00-VP
Other · Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Phase 1 Interventional Accepts healthy volunteers

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

NCT06999434
Conditions
Alzheimer's Disease (AD), Demyelinating Disorders, MCI, MS (Multiple Sclerosis), SCI - Spinal Cord Injury, Spinal Radiculopathy
Interventions
[ 18F]3F4AP, [11C]PIB, [18F]MK6240
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 90 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Psychiatric Disorder
Interventions
Cranial Electrical Stimulation (CES), Discussion, Health and Wellness Coach, Informational Intervention, Sham Intervention
Procedure · Other · Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Adolescent Drinking, Cannabis Use
Interventions
Chat, Enhanced Usual Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 19 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
Commerce, California • North Hollywood, California • Pittsburgh, Pennsylvania
Conditions
Exercise, Gut Microbiome, Gut Microbiota, Health, Metabolome, Obesity, Weight Management, Women
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Aging With a Ketone Ester for Function in Frailty

NCT06645847
Conditions
Aging, Frail Elderly, Immune Function, Muscle Function
Interventions
Ketone ester, Placebo Comparator: Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Novato, California • Farmington, Connecticut • Columbus, Ohio
Conditions
Control Subjects, Language, Reading
Interventions
Sham Stimulation, cTBS, iTBS
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Recruiting Not applicable Interventional Accepts healthy volunteers

Cottonseed Oil Versus Matched PUFA Effects

NCT06382298
Conditions
Dyslipidemia, Nutrition, Healthy, Overweight and Obesity
Interventions
CONTROL, COTTONSEED OIL, MATCHED PUFA DIET
Other
Lead sponsor
University of Georgia
Other
Eligibility
25 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Gender Identity, Health Services for Transgender Persons, Transgender Persons
Interventions
Interactive educational digital platform for transgender and gender-diverse (TGD) young adults and caregivers
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Phase 2 Interventional Accepts healthy volunteers

Tranexamic Acid in Nasal Mohs Reconstruction

NCT06057675
Conditions
Postoperative Bleeding, Skin Cancer Face
Interventions
Control (1% lidocaine with 1:100,000 epinephrine), Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine)
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting Phase 1 Interventional Accepts healthy volunteers

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

NCT05985681
Conditions
Human Papillomavirus-Related Carcinoma
Interventions
Biospecimen Collection, HPV16 RG1 VLP Vaccine, Questionnaire Administration, Recombinant Human Papillomavirus Nonavalent Vaccine
Procedure · Biological · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 60 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin