Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

The live registry is temporarily unavailable. These stored records may be incomplete or out of date. Check the official record for current status and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 3:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5023
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1021–1032 of 5,023 healthy volunteer trials.
Indexed local directory records.

Stored official records

Recruiting Not applicable Interventional Accepts healthy volunteers

Objectively Diagnose and Monitor Treatment of Light Sensitivity

NCT03694626
Conditions
Migraine, Photophobia, Traumatic Brain Injury
Interventions
Electrophysiology, Ocular Coherence Tomography (OCT), Pupillography, Videography, Wrist-watch sensor device
Device
Lead sponsor
Randy Kardon
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Recruiting Not applicable Interventional Accepts healthy volunteers

New Non-invasive Modalities for Assessing Retinal Structure and Function

NCT03475173
Conditions
Acute Zonal Occult Outer Retinopathy, Branch Retinal Artery Occlusion, Hemianopia, Ischemic Optic Neuropathy, Leber Hereditary Optic Neuropathy
Interventions
LSFG-NAVI
Device
Lead sponsor
Randy Kardon
Other
Eligibility
18 Years to 99 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Developmental Delay
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
9 Months to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Inflammation, Diabetes, Ethnicity and Obesity Cohort

NCT03022682
Conditions
Diabetes Mellitus, Obesity, Pre Diabetes
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2029
U.S. locations
1
States / cities
San Francisco, California
Recruiting No phase listed Observational Accepts healthy volunteers

Alzheimer's Disease Genetics Study

NCT00064870
Conditions
Alzheimer Disease, Dementia, Late Onset Alzheimer Disease
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2031
U.S. locations
1
States / cities
Nationwide, Indiana
Conditions
Obesity, Overweight
Interventions
NNC0721-8060, Placebo, Semaglutide
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 55 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Lenexa, Kansas • San Antonio, Texas
Conditions
Healthy Participants, Hepatic Impairment
Interventions
Casdatifan
Drug
Lead sponsor
Arcus Biosciences, Inc.
Industry
Eligibility
18 Years to 84 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Options At Pantries (HOAP) Study

NCT07729436
Conditions
Behavioral Economics, Diet, Healthy, Food Choice, Food Insecurity, Implementation Science
Interventions
Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting No phase listed Observational Accepts healthy volunteers

Quality of End-of-Life Care for Children With Cancer

NCT07412002
Conditions
Childhood Hematopoietic and Lymphatic System Neoplasm, Childhood Malignant Solid Neoplasm
Interventions
Non-Interventional Study
Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
18 Years and older
Enrollment
2,425 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
28
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Oakland, California + 25 more
Conditions
Ethnic Minority, Intervention Study, Sleep, Sleep Quality
Interventions
SIESTA, Sleep education and health education control
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Phase 1 Interventional Accepts healthy volunteers

High Potency Cannabis: Acute and Protracted Effects

NCT06859723
Conditions
Abuse Cannabis, Pain, Pharmacokinetics
Interventions
High dose THC, Low dose THC, Placebo Comparator: Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Reproductive Health, Sexual Risk Behavior for HIV-infection
Interventions
Generic Information, PrEP Decision Aid
Other · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut