Institution Directory

Clinical trials at Children's Hospital of Philadelphia

Sites in Philadelphia, PA

Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 12:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

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Conditions: Acute Respiratory Distress Syndrome in Children
Interventions: Either supine or prone positioning and either CMV or HFOV; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 2 Weeks to 20 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 28
States / cities: Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 24 more

Conditions: Point of Care STI Testing
Interventions: Gonorrhea/chlamydia Point-of-Care Testing; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 16 Years to 24 Years
Enrollment: 6,460 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Parent-Child Relations, Child Maltreatment
Interventions: PriCARE/CARIÑO; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Months to 99 Years
Enrollment: 1,932 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Philadelphia, Pennsylvania

Conditions: Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
Interventions: Endoscopic Balloon Dilation; Procedure
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 18 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Boston, Massachusetts • Philadelphia, Pennsylvania

Conditions: Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Interventions: Not listed
Lead sponsor: University of Iowa; Other
Eligibility: 4 Years to 30 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 5
States / cities: Sacramento, California • Iowa City, Iowa • Philadelphia, Pennsylvania + 2 more

Conditions: Multiple Sclerosis
Interventions: Not listed
Lead sponsor: University of Virginia; Other
Eligibility: 10 Years to 20 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Charlottesville, Virginia

Conditions: Friedreich Ataxia
Interventions: Omaveloxolone; Drug
Lead sponsor: Biogen; Industry
Eligibility: 16 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 4
States / cities: Los Angeles, California • Aurora, Colorado • Gainesville, Florida + 1 more

Conditions: Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency, Citrullinemia 1, ARGI Deficiency, ASL Deficiency, Argininosuccinic Aciduria, ASS Deficiency, Hyperargininemia
Interventions: Not listed
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 6 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 5
States / cities: Aurora, Colorado • Washington D.C., District of Columbia • Philadelphia, Pennsylvania + 2 more

Conditions: Sickle Cells Disease
Interventions: Red cell units that are genotype matched at the RHD and RHCE loci; Biological
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 6 Months and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: Ruxolitinib, Dexamethasone, Etoposide; Drug
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 6 Weeks to 22 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 13
States / cities: Phoenix, Arizona • Orange, California • San Francisco, California + 10 more

Conditions: Congenital Disorders, Cerebral Desaturation, Neonatal Surgery
Interventions: NIRS/EEG monitoring; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Up to 60 Weeks
Enrollment: 900 participants
Timeline: 2022 – 2027
U.S. locations: 4
States / cities: New York, New York • Philadelphia, Pennsylvania • Dallas, Texas + 1 more

Conditions: Dermatitis Atopic
Interventions: Amlitelimab; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 12 Years and older
Enrollment: 999 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2031
U.S. locations: 22
States / cities: Birmingham, Alabama • Litchfield Park, Arizona • Bryant, Arkansas + 17 more

About this Children's Hospital of Philadelphia institution page

What this page lists: ClinicalTrials.gov records that list Children's Hospital of Philadelphia in Philadelphia, PA as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status: A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.

Clinical trials at Children's Hospital of Philadelphia

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Live official records

PROSpect: Prone and Oscillation Pediatric Clinical Trial

Point of Care STI Testing

Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)

Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease

Obesity and Pediatric Multiple Sclerosis

A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own Doctors

Liver Disease in Urea Cycle Disorders

RH Genotype Matched RBC Transfusions

Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis

International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

About this Children's Hospital of Philadelphia institution page