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Clinical trials at Children's Hospital of Philadelphia

Sites in Philadelphia, PA

Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 11:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
599
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Children's Hospital of Philadelphia, Philadelphia, PA
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Showing 565–576 of 599 matching trials with a site at Children's Hospital of Philadelphia, Philadelphia, PA.
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Live official records

Active, not recruiting Phase 1Phase 2 Interventional

A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children

NCT02637687
Site status not listed — check the official record
View directory record Official record
Conditions
Solid Tumors Harboring NTRK Fusion
Interventions
Larotrectinib (Vitrakvi, BAY2757556)
Drug
Lead sponsor
Bayer
Industry
Eligibility
Up to 21 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Palo Alto, California • Orlando, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Recruiting No phase listed Observational

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

NCT02852031
Status at this site: Recruiting
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome (HLHS)
Interventions
Collaborative Learning Network
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 15 Months
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
61
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 53 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Results available

PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

NCT03817320
Site status not listed — check the official record
View directory record Official record
Conditions
ALL, Childhood, Lymphoblastic Lymphoma, Childhood, Lymphoblastic Leukemia, Acute, Childhood
Interventions
Ixazomib, Vincristine, Dexamethasone, Asparaginase, Doxorubicin, Methotrexate (IT), Triple IT (Methotrexate, Hydrocortisone, Cytarabine), Leucovorin
Drug
Lead sponsor
Therapeutic Advances in Childhood Leukemia Consortium
Other
Eligibility
1 Year to 21 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
17
States / cities
Los Angeles, California • Orange, California • Washington D.C., District of Columbia + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Recruiting Not applicable Interventional

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

NCT06216899
Status at this site: Not yet recruiting
View directory record Official record
Conditions
Crohn Disease
Interventions
Whole-food based smoothie, Formula
Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
8 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Not yet recruiting Not applicable Interventional

A Multi-Site Hybrid Type I Effectiveness-Implementation Randomized Trial of an Emergency Care Action Plan for Infants With Medical Complexity

NCT06993129
Site status not listed — check the official record
View directory record Official record
Conditions
Chronic Disease Management, Infants Health, Emergency, Utilization, Health Care, Caregiver Stress
Interventions
Emergency Care Action Plan
Other
Lead sponsor
University of Vermont
Other
Eligibility
0 Months to 6 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
4
States / cities
Aurora, Colorado • Cincinnati, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Recruiting No phase listed Observational

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

NCT06389994
Status at this site: Recruiting
View directory record Official record
Conditions
Eosinophilic Esophagitis (EoE)
Interventions
Esophageal String Test
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
7 Years to 17 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Recruiting No phase listed Observational

The Pediatric Anesthesia Quality Improvement Project

NCT00674388
Status at this site: Recruiting
View directory record Official record
Conditions
Surgery, Anesthesia, Children
Interventions
Not listed
Lead sponsor
The Society for Pediatric Anesthesia
Other
Eligibility
Up to 21 Years
Enrollment
5,000,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2040
U.S. locations
37
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pediatric ACL: Understanding Treatment Options

NCT02772770
Site status not listed — check the official record
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction, Surgical technique: Physeal sparing reconstruction by the Anderson method, Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method
Other · Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
765 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
10
States / cities
Palo Alto, California • San Diego, California • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

NCT04591392
Site status not listed — check the official record
View directory record Official record
Conditions
Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities
Interventions
reSept ASD Occluder
Device
Lead sponsor
atHeart Medical
Industry
Eligibility
Up to 84 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
24
States / cities
Birmingham, Alabama • Los Angeles, California • Thousand Oaks, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting Phase 3 Interventional

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

NCT02616484
Site status not listed — check the official record
View directory record Official record
Conditions
Pyruvate Dehydrogenase Complex Deficiency
Interventions
Dichloroacetate (DCA), Placebo, Genotype
Drug · Other · Genetic
Lead sponsor
Saol Therapeutics Inc
Industry
Eligibility
6 Months to 17 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
10
States / cities
Orange, California • Stanford, California • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2

NCT01208389
Site status not listed — check the official record
View directory record Official record
Conditions
Leber Congenital Amaurosis
Interventions
voretigene neparvovec-rzyl
Biological
Lead sponsor
Spark Therapeutics, Inc.
Industry
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 31, 2026, 11:25 AM EDT
Active, not recruiting Phase 3 Interventional Results available

Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

NCT00999609
Site status not listed — check the official record
View directory record Official record
Conditions
Inherited Retinal Dystrophy Due to RPE65 Mutations, Leber Congenital Amaurosis
Interventions
AAV2-hRPE65v2,voretigene neparvovec-rzyl
Biological
Lead sponsor
Spark Therapeutics, Inc.
Industry
Eligibility
3 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2030
U.S. locations
2
States / cities
Iowa City, Iowa • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 31, 2026, 11:25 AM EDT

About this Children's Hospital of Philadelphia institution page

What this page lists
ClinicalTrials.gov records that list Children's Hospital of Philadelphia in Philadelphia, PA as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status
A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from
Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do
No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.

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