- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
Search Results
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Showing 25–48
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- Conditions
- ACL Injuries
- Interventions
- MC-synced NTP, Blinded NTP
- Other
- Lead sponsor
- Sophia Ulman
- Other
- Eligibility
- 13 Years to 19 Years · Female only
- Enrollment
- 148 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Neuromuscular Electrical Stimulation (NMES), Eccentric Exercise (ECC), Neuromuscular Electrical Stimulation (NMES) placebo, Eccentric Exercise (ECC) placebo
- Device · Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Regenexx SD, Exercise Therapy
- Procedure · Other
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Interventions
- Autologous Bone Marrow Derived Mesenchymal Stem Cells, Sham incision
- Device · Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- KneeStim
- Device
- Lead sponsor
- Keller Army Community Hospital
- Federal
- Eligibility
- 17 Years to 27 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- West Point, New York
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injury
- Interventions
- Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
- Procedure · Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
- Interventions
- Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction
- Biological · Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • New York, New York
- Conditions
- ACL Injury
- Interventions
- PET scan, MRI scan
- Device
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2024
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 40 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL, ACL Injury
- Interventions
- Healthy Minds Program (HMP) App
- Behavioral
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Interventions
- neuromuscular warm-up
- Other
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- 14 Years to 80 Years
- Enrollment
- 1,653 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Internal focus of attention feedback, Visual internal focus of attention feedback, Auditory external focus of attention feedback
- Other
- Lead sponsor
- University of North Carolina, Charlotte
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- ACL, Anterior Cruciate Ligament Injury
- Interventions
- Neuromuscular and Resistance Training
- Procedure
- Lead sponsor
- Ohio University
- Other
- Eligibility
- 18 Years to 20 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Athens, Ohio
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy, Muscle Atrophy or Weakness
- Interventions
- Zynex NexWave Electrotherapy Device
- Device
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
- Interventions
- Not listed
- Lead sponsor
- Sanford Health
- Other
- Eligibility
- 10 Years to 65 Years
- Enrollment
- 5,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2033
- U.S. locations
- 1
- States / cities
- Fargo, North Dakota
- Conditions
- Depression, Anterior Cruciate Ligament Injuries, Mental Health Issue
- Interventions
- Virtual Psychological Intervention: Cognitive Behavioral Therapy
- Behavioral
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 13 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Connecticut Children's Medical Center
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Anterior Cruciate Ligament Tear, Knee Meniscus Tear
- Interventions
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine, Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.
- Procedure · Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- silk fibroin-based incision dressing, cyanoacrylate-based closure system
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 14 Years to 60 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Injuries, Anterior Cruciate Ligament (ACL) Reconstruction
- Interventions
- OrthoPure™ XT
- Device
- Lead sponsor
- TRX Orthopedics
- Industry
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Greenwood, Indiana • Louisville, Kentucky
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Interventions
- IPACK, PLACEBO
- Drug
- Lead sponsor
- Loyola University
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Maywood, Illinois
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Operant Conditioning, Control
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Tear
- Interventions
- Mental Skills Coaching
- Behavioral
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 8 Years to 25 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Waltham, Massachusetts