- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 95
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Oxycodone, Placebo oral tablet
- Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 14 Years to 40 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 3
- States / cities
- Atlanta, Georgia • Tucker, Georgia
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Initial graft tension during ACL reconstruction surgery
- Procedure
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2024
- U.S. locations
- 2
- States / cities
- Providence, Rhode Island
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Interventions
- Exercise Group
- Other
- Lead sponsor
- Johanna M. Hoch
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
- Interventions
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Physical Therapy
- Interventions
- Arm A - blood flow restriction training, Arm B - standard of care
- Other
- Lead sponsor
- Brian W. Noehren
- Other
- Eligibility
- 15 Years to 40 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
- Interventions
- Joint Manipulation
- Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 35 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
- Interventions
- Blood flood restriction cuff
- Device
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- West Bloomfield, Michigan
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
- Interventions
- dispense of study drug, Ketorolac
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 15 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- Coral Springs, Florida • Garfield, Ohio • Strongsville, Ohio
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- anakinra (150mg), Saline intraarticularly
- Drug · Other
- Lead sponsor
- Cale Jacobs, PhD
- Other
- Eligibility
- 14 Years to 40 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- ACL - Anterior Cruciate Ligament Rupture
- Interventions
- Bio-ACL, amnion wrap and BMAC
- Procedure · Device
- Lead sponsor
- Andrews Research & Education Foundation
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
- Interventions
- Anterior cruciate ligament reconstruction
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Tear
- Interventions
- NMES and BFR, Standard physical therapy
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Sunnyvale, California
- Conditions
- Rupture of Anterior Cruciate Ligament
- Interventions
- Somatropin, Placebo
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 35 Years · Male only
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Rupture of Anterior Cruciate Ligament
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 12 Years to 35 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Sciatic Block, Femoral Block only
- Procedure
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Rupture of Anterior Cruciate Ligament
- Interventions
- cryotherapy, TENS
- Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 15 Years to 55 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- ACL Tear
- Interventions
- ACL reconstruction, Mesenchymal stem cell implantation
- Procedure
- Lead sponsor
- Andrews Research & Education Foundation
- Other
- Eligibility
- 14 Years to 50 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida
- Conditions
- ACL Tear, Opioid Misuse, Pain, Anxiety
- Interventions
- Exparel
- Drug
- Lead sponsor
- Children's Hospital of Orange County
- Other
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 96 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Orange, California
- Conditions
- Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
- Interventions
- Metformin, Placebo
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 512 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 9
- States / cities
- Atlanta, Georgia • Iowa City, Iowa • Lexington, Kentucky + 6 more
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Osteo Arthritis Knee
- Interventions
- Internal focus of attention feedback, External focus of attention feedback
- Other
- Lead sponsor
- University of North Carolina, Charlotte
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injury
- Interventions
- Platelet Rich Plasma, Saline Placebo
- Biological · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- The BEAR® Implant
- Device
- Lead sponsor
- Miach Orthopaedics
- Industry
- Eligibility
- 14 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 8
- States / cities
- Redwood City, California • Steamboat Springs, Colorado • Orlando, Florida + 5 more
- Conditions
- ACL Tears
- Interventions
- Anterior cruciate ligament reconstruction with BioBrace® augmentation, Arthroscopic anterior cruciate ligament reconstruction
- Device · Procedure
- Lead sponsor
- CONMED Corporation
- Industry
- Eligibility
- 14 Years to 70 Years
- Enrollment
- 500 participants
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut