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Showing 1–24 of 211 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: ACT Clear all
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A Study to Learn How Different Amounts of the Study Medicine Called PF-08049820 Are Tolerated and Act in the Body in Healthy Adults

NCT06686797
View directory record Official record
Conditions
Healthy
Interventions
PF-08049820, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of ACT OUT! Social Issue Theater on Youth and Adolescents

NCT04097496
View directory record Official record
Conditions
Social Competence, Bullying
Interventions
Act Out! Intervention
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
1,537 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Jul 22, 2026, 9:03 AM EDT
Active, not recruiting Not applicable Interventional

The Effect of Electroacupuncture on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)

NCT04917796
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful, Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy
Interventions
Electroacupuncture, Sham Acupuncture
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Boston, Massachusetts • Basking Ridge, New Jersey • Middletown, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Withdrawn Phase 4 Interventional

Pharmacokinetic,Safety and Exploratory Efficacy of RECTIV® in Adolescents With Chronic Anal Fissure

NCT01920074
View directory record Official record
Conditions
Anal Fissure
Interventions
Nitroglycerin Ointment 0.4%
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
12 Years to 16 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Los Angeles, California • Miami, Florida • Orlando, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 3, 2015 · Synced Jul 22, 2026, 9:03 AM EDT
Suspended Not applicable Interventional

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)

NCT04866810
View directory record Official record
Conditions
Melanoma
Interventions
Intervention Arm, Control
Behavioral
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Loma Linda, California • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Development and Pilot Trial of Focused ACT (FACT) for Patients With Advanced Cancer

NCT07105033
View directory record Official record
Conditions
Advanced Cancer
Interventions
FACT Session, Enhanced Usual Care and Assessments
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences

NCT06075446
View directory record Official record
Conditions
Child Abuse
Interventions
ACT Raising Safe Kids
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Learn How Different Amounts of the Study Medicine Called PF-07328948 Are Tolerated and Act in the Body in Healthy Adults

NCT05807490
View directory record Official record
Conditions
Healthy
Interventions
PF-07328948, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Jul 22, 2026, 9:03 AM EDT
Active, not recruiting Phase 1 Interventional

Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors

NCT05902520
View directory record Official record
Conditions
HNSCC, Melanoma, Gynecologic Cancer, Colorectal Cancer, Lung Cancer, Urogenital Cancer
Interventions
DP CD8 TIL, DP CD8 TIL KD, Low dose IL-2
Biological
Lead sponsor
AgonOx, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional

One-Day Intervention for Depression and Impairment in Migraine Patients

NCT02108678
View directory record Official record
Conditions
Migraine, Depression
Interventions
ACT-ME, Migraine Education Only
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

NCT05897242
View directory record Official record
Conditions
Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping, Vaping
Interventions
Smartphone app, Text Message, Survey Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study: Stress Reduction in Caregivers of Children With ASD Using ACT

NCT05944289
View directory record Official record
Conditions
Caregiver Stress
Interventions
Acceptance and Commitment Therapy, Caregiver Support Group
Behavioral
Lead sponsor
Fielding Graduate University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Phase Clinical Trial to Test the Feasibility of an ACT-based Physical Activity Promotion Program for Adults With Depressive Symptoms

NCT05407935
View directory record Official record
Conditions
Physical Inactivity
Interventions
ACTivity, Relaxercise
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Terminated Phase 2 Interventional Results available

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

NCT06630325
View directory record Official record
Conditions
Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm, Advanced Ovarian Carcinoma, Advanced Pancreatic Carcinoma, Advanced Prostate Carcinoma, Advanced Sarcoma, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
Interventions
Abemaciclib, Biopsy, Bone Scan, Echocardiography, Exemestane, Gemcitabine, Letrozole, Multigated Acquisition Scan, Osimertinib, Pemetrexed, Survey Administration, Tamoxifen, Biospecimen Collection
Drug · Procedure · Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Acute Kidney Injury In Care Transitions (ACT): Pragmatic Clinical Trial

NCT07670520
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Acute Kidney Injury in Care Transitions (ACT), Usual Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Mankato, Minnesota • Rochester, Minnesota • Eau Claire, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Chronic Pain in SCI: Development and Testing of an eHealth Program

NCT06098170
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Unguided use of the My SCI Toolkit program, Coached My SCI Toolkit
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional

ACT Workshops: A Novel Delivery Modality to Increase Access to Care for Rural Veterans

NCT05196464
View directory record Official record
Conditions
Access to Care, Psychological Distress
Interventions
Acceptance and Commitment Therapy (ACT) Workshop, Treatment as usual (TAU)
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2024 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

Developing an Online Therapeutic Intervention for Chronic Pain in Veterans

NCT03655132
View directory record Official record
Conditions
Chronic Pain
Interventions
Veteran Acceptance and Commitment Therapy for Chronic Pain
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 22, 2026, 9:03 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

ACT NOW Longitudinal Study: Outcomes of Babies With Opioid Exposure Study

NCT04149509
View directory record Official record
Conditions
Neonatal Opioid Withdrawal Syndrome
Interventions
Not listed
Lead sponsor
Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Network
Eligibility
Up to 1 Month
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
6
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Completed No phase listed Observational

Post Affordable Care Act Evaluation

NCT02657499
View directory record Official record
Conditions
Chronic Disease
Interventions
Medicaid Expansion
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 64 Years
Enrollment
1,939,848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional

A Guided Online ACT Intervention Combined With Psychoeducation for People With Spinal Cord Injury

NCT04670406
View directory record Official record
Conditions
Spinal Cord Injuries, Psychological Distress
Interventions
acceptance and commitment therapy (ACT) combined with psychoeducation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 7, 2021 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adjustable Continence Therapy (ACT) Device for the Treatment of Female Stress Urinary Incontinence

NCT00113555
View directory record Official record
Conditions
Urinary Incontinence
Interventions
ACT (Adjustable Continence Therapy)
Device
Lead sponsor
Uromedica
Industry
Eligibility
18 Years and older · Female only
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2010
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Burlington, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2018 · Synced Jul 22, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients

NCT04423939
View directory record Official record
Conditions
Hematopoietic Steam Cell Transplantation (HCT)
Interventions
Acceptance and Commitment Therapy (ACT)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jul 22, 2026, 9:03 AM EDT
Not listed Not applicable Interventional

Anger Control Therapy (ACT) With RAGE-Control: An Outpatient Videogame-assisted Therapy for the Treatment of Anger

NCT01551732
View directory record Official record
Conditions
Anger, Aggression
Interventions
ACT, ACT with RAGE-Control
Behavioral
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
10 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Jul 22, 2026, 9:03 AM EDT