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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: AI (Artificial Intelligence) Clear all
Recruiting Not applicable Interventional

Evaluating Conversational Artificial Intelligence for Depression Management

NCT07105397
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Conversational AI system vs Usual Care
Other
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Active, not recruiting No phase listed Observational

Evaluating the Real World Performance of an AI Based Lung Nodule Detection Tool

NCT06597968
View directory record Official record
Conditions
Lung Nodule
Interventions
AI Based CAD Software (qXR-Ln)
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
44,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

NCT06924021
View directory record Official record
Conditions
Age-Related Macular Degeneration
Interventions
Retinal Imaging
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
7
States / cities
Fargo, North Dakota • Erie, Pennsylvania • Dallas, Texas + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Active, not recruiting No phase listed Observational

Leveraging EA8191 to Assess AI-Augmented EHR Abstraction

NCT06561230
View directory record Official record
Conditions
Prostate Cancer
Interventions
Chart review
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Male only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

NCT05802186
View directory record Official record
Conditions
Lung Carcinoma, Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
Interventions
Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Quality-of-Life Assessment, Radiology, Treatment Planning, Stereotactic Body Radiation Therapy, X-Ray Imaging
Procedure · Other · Radiation
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting No phase listed Observational

Behavioral AI to Predict and Increase Peritoneal Dialysis Uptake

NCT06533254
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Predicting choice of dialysis, Behavioral nudges
Other · Behavioral
Lead sponsor
Scaled Insights
Industry
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 24, 2026, 9:05 PM EDT
Completed Not applicable Interventional

ANCHOR Validation Trial in High-Risk Multidisciplinary Care

NCT07597499
View directory record Official record
Conditions
High-Risk Multidisciplinary Care, Clinical Decision Support, Artificial Intelligence-Assisted Care, Telemedicine
Interventions
Gemini 3.1 Pro with Safety Prompt, ANCHOR Clinical AI Verification Layer (with Gemini 3.1 Pro)
Behavioral
Lead sponsor
Waymark
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Crowdsourcing an Open COVID-19 Imaging Repository for AI Research

NCT05384912
View directory record Official record
Conditions
COVID-19
Interventions
Not listed
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting No phase listed Observational

Implementing AI-Assisted, Patient-Friendly Imaging Report Summaries to Enhance Oncology Care Delivery

NCT07532083
View directory record Official record
Conditions
Oncology
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Completed Not applicable Interventional

Safety and Efficacy Study of AI LVEF

NCT05140642
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure, Diastolic
Interventions
Automated annotation of the left ventricle through deep learning, Sonographer Measurement of LVEF
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 110 Years
Enrollment
3,495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Sep 24, 2026, 9:05 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

OpenEvidence Safety and Comparative Efficacy of Four LLM's in Clinical Practice

NCT07199231
View directory record Official record
Conditions
AI (Artificial Intelligence), Large Language Model, Generative Artificial Intelligence
Interventions
AI clinical reference tool
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Not yet recruiting No phase listed Observational

A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment

NCT07814872
View directory record Official record
Conditions
Neoplasms (Cancer / Tumors), Colorectal Neoplasms, Lung Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Pancreatic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Glioma, Ovarian Neoplasms, Stomach Neoplasms
Interventions
Not listed
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
Not listed
Enrollment
30,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting No phase listed Observational

AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma

NCT06320717
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
Blood sample
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Buffalo, New York • West Islip, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

AI Noise Reduction in Phonak Hearing Aids

NCT06743295
View directory record Official record
Conditions
Hearing Loss
Interventions
DEEPSONIC™ Deep Sound Optimized Neural Integrated Chip Artificial intelligence-based noise reduction
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 110 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Not yet recruiting Not applicable Interventional

Artificial Intelligence-based Methods to Predict Disease Progression in Youth With Type 2 Diabetes

NCT07116902
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
phone application, Standard of Care (SOC)
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

NCT07232043
View directory record Official record
Conditions
Cancer
Interventions
MatchMiner-AI Artificial Intelligence Tool
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
70,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conversations With AI Chatbots Increase Short-Term Vaccine Intentions But Do Not Outperform Standard Public Health Messaging

NCT07132125
View directory record Official record
Conditions
HPV Vaccination Intent
Interventions
Default-style LLM chatbot, Conversational-style LLM chatbot, Public health informational materials
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
930 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 24, 2026, 9:05 PM EDT
Not listed No phase listed Observational

Development of an AI App to Improve Compliance in Periodontal Maintenance Patients

NCT05068778
View directory record Official record
Conditions
Periodontal Diseases
Interventions
Artificial Intelligence Application
Behavioral
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Timeline
2021 – 2023
U.S. locations
2
States / cities
La Vista, Nebraska • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 24, 2026, 9:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Prospective Randomized Study Comparing the Adenoma Detection Yield of SC, AI and Combined AI and G-EYE®

NCT05317351
View directory record Official record
Conditions
Colorectal (Colon or Rectal) Cancer, Adenoma
Interventions
Standard Colonoscopy, Artificial Intelligence Aided Colonoscopy (GI Genius™), Combined Artificial Intelligence Aided Colonoscopy (GI Genius™) and G-EYE® Balloon Aided Colonoscopy
Device
Lead sponsor
Smart Medical Systems Ltd.
Industry
Eligibility
45 Years and older
Enrollment
2,160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Indianapolis, Indiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Sep 24, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

AI-Based Mobile Intervention on Medication Non-Adherence and Transition

NCT07445074
View directory record Official record
Conditions
Epilepsy, Seizure
Interventions
Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
Other
Lead sponsor
University of Central Florida
Other
Eligibility
14 Years to 24 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Completed No phase listed Observational

Multi-center Database Registry to Study Thalamus Changes Using AI in MS

NCT03920995
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 85 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 24, 2026, 9:05 PM EDT
Completed Not applicable Interventional

Assess Patient Readiness for Pelvic Ultrasound With the Use of Artificial Intelligence

NCT07535294
View directory record Official record
Conditions
Abdominal Pain, Pelvic Pain
Interventions
Experimental AI POCUS, Standard of Care Ultrasound
Other · Diagnostic Test
Lead sponsor
Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Other
Eligibility
8 Years to 21 Years · Female only
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Not yet recruiting Not applicable Interventional

Effectiveness of Artificial-Intelligence (AI) Bolus Priming Added to an Existing Fully Automated Control Algorithm (AIDANET)

NCT07517770
View directory record Official record
Conditions
Type 1 Diabetes Mellitis
Interventions
Hybrid Closed Loop (HCL) x 2 weeks, AIDANET x 2 weeks, AIDANET AI x 4 weeks
Device
Lead sponsor
Sue Brown
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 24, 2026, 9:05 PM EDT
Not yet recruiting No phase listed Observational

A Prospective Analysis To Assess The Potential Use Of ECGio In Clinical Practice

NCT07405866
View directory record Official record
Conditions
AI-algorithm Usage
Interventions
AI-Assistive Algorithm
Device
Lead sponsor
Heart Input Output Inc
Industry
Eligibility
18 Years to 89 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
4
States / cities
Bensalem, Pennsylvania • Philadelphia, Pennsylvania • Springfield, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 24, 2026, 9:05 PM EDT