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Showing 1–24 of 467 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Anesthesia
Interventions
Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Arthritis
Interventions
Total knee arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
3
States / cities
Denver, Colorado • Pittsburgh, Pennsylvania • Virginia Beach, Virginia
Conditions
ARTHROPLASTY, REPLACEMENT
Interventions
PACE, Delayed PACE
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Total Joint Replacement Surgery
Interventions
VERA clinic
Device
Lead sponsor
Derek Amanatullah
Other
Eligibility
18 Years to 99 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Redwood City, California
Conditions
Pain, Chronic, Knee Pain Chronic
Interventions
Pain reprocessing therapy (PRT), Usual care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • New York, New York
Conditions
Osteoarthritis, Knee
Interventions
Intracapsular Injection, Periarticular Injection
Procedure
Lead sponsor
Broward Health
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Conditions
Postoperative Pain
Interventions
Buprenorphine transdermal patch, Placebo BTDS
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
Phoenix, Arizona • San Clemente, California • Orlando, Florida + 2 more
Conditions
Osteoarthritis
Interventions
Ropivacaine infiltration and saline infusion., Ropivacaine infiltration and infusion., Normal Saline
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Terminated Not applicable Interventional Results available

Omnifit Hydroxylapatite (HA) Hip Outcomes Study

NCT00958347
Conditions
Arthroplasty, Replacement, Hip
Interventions
Omnifit HA Hip Stem
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1987 – 2011
U.S. locations
3
States / cities
Indianapolis, Indiana • New York, New York • Moon Township, Pennsylvania
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Computer Assisted Navigation Knee Replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Technology Interventions to Improve Outcomes After Knee Replacement

NCT04482400
Conditions
Knee Arthroplasty
Interventions
NEAT!2, MyKneeGuide
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
40 Years to 79 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbia, South Carolina
Completed Not applicable Interventional Results available

Functional Movement Retraining After Hip Replacement

NCT01878175
Conditions
Arthroplasty, Replacement, Hip
Interventions
Functional Movement Retraining
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Durham, North Carolina
Conditions
Total Joint Replacement Surgery
Interventions
SPARTA force plate
Device
Lead sponsor
Derek Amanatullah
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy

NCT04889833
Conditions
Anxiety, Opioid Use
Interventions
hypnosis therapy
Behavioral
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Surgical and Economical Parameters of Total Knee Replacement.

NCT03427047
Conditions
Osteo Arthritis Knee, Total Knee Arthroplasty
Interventions
MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
Device
Lead sponsor
Medacta USA
Industry
Eligibility
16 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Pain, Osteoarthritis
Interventions
Canal Block and Capsular Injection, Femoral Nerve Block with Tibial Nerve Block
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Arthroplasty, Replacement, Knee, Total Knee Arthroplasty
Interventions
Lidocaine IV, Saline IV
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Phase 4 Interventional Results available

Antibiotic Elution in Total Knee Arthroplasty

NCT03928522
Conditions
Total Knee Replacement
Interventions
hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin
Drug · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Energize! Study for Adults With Knee Replacement

NCT06096727
Conditions
Knee Arthroplasty
Interventions
Energize!
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Pain, Postoperative
Interventions
No specific treatment based intervention-health measurement instrument
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Knee Osteoarthritis, Arthroplasty Complications
Interventions
Treadmill-based perturbation training, Education Control
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Total Knee Replacement
Interventions
Clinical decision support (CDS) tool
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Total Knee Arthroplasty (Postoperative Pain)
Interventions
ATX101, bupivacaine hydrochloride, saline placebo
Drug
Lead sponsor
Allay Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
11
States / cities
Little Rock, Arkansas • Tamarac, Florida • Atlanta, Georgia + 7 more