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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Abortion in First Trimester Clear all
Completed Not applicable Interventional Accepts healthy volunteers

4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions

NCT00121329
View directory record Official record
Conditions
Pain
Interventions
Intrauterine lidocaine infusion 4%
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2004
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 20, 2005 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Non-Pharmacologic Patient Centered Pain Control Adjuncts During First Trimester Abortion

NCT02590146
View directory record Official record
Conditions
Pregnancy Termination, Pain Management
Interventions
Non-pharmacologic pain control adjuncts
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Use of Music for Pain and Anxiety Control During Abortion

NCT01013363
View directory record Official record
Conditions
Pain, Anxiety
Interventions
iPod Nano digital music player
Other
Lead sponsor
Columbia University
Other
Eligibility
Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2012 · Synced Jul 21, 2026, 5:13 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Mifepristone vs Misoprostol

NCT06502158
View directory record Official record
Conditions
Cervical Preparation
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl

NCT02536235
View directory record Official record
Conditions
Topical Heat Application for Intraoperative Abortion Pain Management
Interventions
heat
Other
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
16 Years to 51 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT03925129
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
high frequency TENS treatment, Sham TENS treatment
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Phase 4 Interventional Results available

Hydrocodone For Pain Control in First Trimester Surgical Abortion

NCT01330459
View directory record Official record
Conditions
Pain
Interventions
Hydrocodone/acetaminophen, Placebo, Ibuprofen, Lorazepam, Lidocaine
Drug
Lead sponsor
Elizabeth Micks
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o

NCT03636451
View directory record Official record
Conditions
Abortion, Spontaneous, Abortion in First Trimester, Pain Uterus, Abortion Early, Abortion, Missed
Interventions
40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block, 20cc 1% lidocaine with 2 units of vasopressin paracervical block
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Jul 21, 2026, 5:13 AM EDT
Terminated Not applicable Interventional

Choice of Modality of Follow up for Medication Abortion

NCT04056637
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Choice of follow-up option, Multi-level pregnancy test
Other · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Jul 21, 2026, 5:13 AM EDT
Completed No phase listed Observational

Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia

NCT00583635
View directory record Official record
Conditions
Preeclampsia, Pregnancy Loss
Interventions
Not listed
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Jul 21, 2026, 5:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient Preferences in Anesthesia for Abortion Care

NCT03030443
View directory record Official record
Conditions
Pregnancy Termination in First Trimester
Interventions
Not listed
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pharmacist Provision of Medication Abortion

NCT04956731
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Pharmacist Provision of Medication Abortion
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2024 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management of First Trimester Surgical Abortion

NCT02096575
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Nitrous oxide administration
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

CCT-102 or Expectant Management in Delayed Pregnancy Loss

NCT06121063
View directory record Official record
Conditions
Early Pregnancy Loss, Delayed Pregnancy Loss
Interventions
CCT-102 A and CCT-102 B
Combination Product
Lead sponsor
Conceptra Biosciences, LLC
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
15
States / cities
Tucson, Arizona • San Fernando, California • Panama City, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss

NCT02141555
View directory record Official record
Conditions
Spontaneous Abortion in First Trimester
Interventions
Vaginal Misoprostol, Buccal Misoprostol
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks

NCT03079622
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Electric Vacuum Aspiration, Manual Vacuum Aspiration
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Immediate Start of Progestin Contraceptives in Medical Abortion

NCT01902485
View directory record Official record
Conditions
Contraception
Interventions
Timing of Contraceptive Initiation in Medical Abortion
Other
Lead sponsor
Gynuity Health Projects
Other
Eligibility
Female only
Enrollment
937 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
6
States / cities
Chula Vista, California • Eureka, California • Stamford, Connecticut + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Jul 21, 2026, 5:13 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Research on Equity in Abortion Care by TeleHealth

NCT06787274
View directory record Official record
Conditions
Abortion in First Trimester, Abortion Early, Abortion; Attempted
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years to 64 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 21, 2026, 5:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Comparison of Continuation Rates for Three Hormonal Contraceptive Methods

NCT00253019
View directory record Official record
Conditions
Contraception
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
13 Years to 45 Years · Female only
Enrollment
321 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Jul 21, 2026, 5:13 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion

NCT03508804
View directory record Official record
Conditions
Pain
Interventions
Lidocaine-Prilocaine Cream, Placebo Cream, 1% Lidocaine Paracervical Block
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lidocaine and Pain Management in First Trimester Abortions

NCT00613821
View directory record Official record
Conditions
Pain
Interventions
Lidocaine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 21, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions

NCT02756403
View directory record Official record
Conditions
First Trimester Abortion
Interventions
Azithromycin, Doxycycline, Metronidazole, Placebo
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Jul 21, 2026, 5:13 AM EDT
Terminated Phase 4 Interventional Results available

Methadone and Medication Abortion

NCT04941443
View directory record Official record
Conditions
Pain, Medical Abortion
Interventions
Methadone Pill, Ibuprofen
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Jul 21, 2026, 5:13 AM EDT
Recruiting Phase 2 Interventional

Letrozole and Misoprostol for Early Pregnancy Loss Management

NCT06452719
View directory record Official record
Conditions
Early Pregnancy Loss, Miscarriage in First Trimester, Miscarriage
Interventions
Letrozole, Misoprostol
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Jul 21, 2026, 5:13 AM EDT