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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Abstinence, Sex Clear all
Completed Not applicable Interventional Results available

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1

NCT00249496
View directory record Official record
Conditions
Alcohol Use, Drug Use, Risk Behavior, Sexual Behavior
Interventions
Contingency management, Employment Only
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2017 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students

NCT00167505
View directory record Official record
Conditions
Sexually Transmitted Diseases, Pregnancy, HIV Infections
Interventions
Risk Avoidance Intervention, Risk Reduction Intervention
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
11 Years to 16 Years
Enrollment
1,742 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2010 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Prevention of Alcohol and Risky Sex for Older Teens

NCT03521115
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders, Alcohol Impairment, Alcohol Withdrawal, Alcohol Abstinence, Alcohol; Harmful Use, Sex Behavior, Sexual Aggression, Sexual Harassment, Relation, Interpersonal
Interventions
Smart Choices 4 Teens
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
16 Years to 17 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet-Based Sexual Health Education for Middle School Native American Youth

NCT01303575
View directory record Official record
Conditions
Sexually Transmitted Diseases, Pregnancy, HIV Infections
Interventions
HIV, STI and Pregnancy Prevention Curriculum, Control Curricula
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 14 Years
Enrollment
574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
4
States / cities
Anchorage, Alaska • Phoenix, Arizona • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact

NCT01280136
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
It's Your Game Tech
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 16 Years
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Jun 25, 2026, 11:50 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

QAIAx (AIhealth4U) - AI Public Health Central: Microcity-A (re Quantum AI Agency Aka AI City Hall Project, UPSTO App Nos. 64/074,526, 64/063,557, 63/903,181, 63/729,428

NCT07661823
View directory record Official record
Conditions
Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
Interventions
AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
Behavioral
Lead sponsor
Veterans Recovery Network Inc.
Other
Eligibility
17 Years to 99 Years
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Contingency Management for Cannabis Use for Persons With HIV

NCT04866004
View directory record Official record
Conditions
Marijuana, HIV Infections
Interventions
Contingency Management - Cannabis
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Jun 25, 2026, 11:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Capacity Builders Inc. Navajo Youth Builders Personal Responsibility Education Innovation Strategies Project

NCT04180358
View directory record Official record
Conditions
Sexual Abstinence, Responsible Sex
Interventions
Native STAND, Regular Health/Physical Education Curriculum
Behavioral
Lead sponsor
Capacity Builders Inc.
Other
Eligibility
14 Years to 18 Years
Enrollment
834 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Farmington, New Mexico
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing HIV Risk Among Adolescents: Evaluating Project HEART

NCT02579135
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
Safer Sex, Growth Mindsets
Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Tolerability of the Vaginal Gel PRO 2000/5

NCT00006207
View directory record Official record
Conditions
HIV Infections
Interventions
PRO 2000
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2008 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)

NCT03137082
View directory record Official record
Conditions
Alcohol Abstinence
Interventions
Guanfacine XR 3mgs/daily, Placebo (for guanfacine)
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Jun 25, 2026, 11:50 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sex Differences in the Response to Abstinence From Alcohol.

NCT03827460
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Abstinence from alcohol, Usual drinking, Intravenous Alcohol
Behavioral · Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 35 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 25, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EmpowHer is Prevention Curriculum for Youth Ages 10-15 Years.

NCT06217809
View directory record Official record
Conditions
Abstinence, Sex
Interventions
The intervention curriculum addresses sexual activity, abstinence, and adulthood preparation topics.
Behavioral
Lead sponsor
Alternatives For Girls
Other
Eligibility
10 Years to 15 Years
Enrollment
552 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jun 25, 2026, 11:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study

NCT02302859
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Nicotine Patch, Questionnaires, Pamphlet, Phone Counseling Sessions, Saliva Test, Smart phone
Drug · Behavioral · Other + 1 more
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Jun 25, 2026, 11:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pornography Abstinence and Nocturnal Erections in Adult Men

NCT07618104
View directory record Official record
Conditions
Erection; Incomplete
Interventions
Pornography Abstinence
Behavioral
Lead sponsor
Efforia, Inc
Industry
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents

NCT00640653
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Abstinence-only HIV/STD risk-reduction intervention, Safer-sex-only HIV/STD risk-reduction intervention, Long comprehensive HIV/STD risk-reduction intervention, Short comprehensive HIV/STD risk-reduction intervention, Health promotion control intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
662 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Phase 2 Interventional Results available

Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men

NCT00856323
View directory record Official record
Conditions
Amphetamine-Related Disorders, HIV, HIV Infections
Interventions
Truvada, CM
Drug · Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Cell Phone-Based Program for Abstinence and HIV Risk Prevention

NCT00601237
View directory record Official record
Conditions
HIV Infections
Interventions
HIV-related text messaging, Nutrition-related text messaging
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
16 Years to 20 Years · Male only
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2015 · Synced Jun 25, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

NCT06883097
View directory record Official record
Conditions
Tobacco, Tobacco Abstinence, Smoking Cessation, Smoking Cessation; Tobacco Dependence, Human Immunodeficiency Virus (HIV), Tobacco Dependence Caused by Cigarettes, Cancer Prevention
Interventions
Learn to Quit-HIV (LTQ-H) App, QuitStart
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The S.A.F.E. Study : Computer-Aided Counseling to Prevent Teen Pregnancy/Sexually Transmitted Diseases (STDs)

NCT00151151
View directory record Official record
Conditions
Pregnancy, Sexually Transmitted Diseases
Interventions
Computer-Assisted Motivational Intervention, Didactic Educational Counseling
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 12, 2011 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Early Phase 1 Interventional Results available

PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)

NCT05128071
View directory record Official record
Conditions
Methamphetamine-dependence, Postpartum Abstinence
Interventions
Progesterone, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 25, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

NCT00149669
View directory record Official record
Conditions
Cocaine-Related Disorders, Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
Interventions
employment-based reinforcement
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jun 25, 2026, 11:50 AM EDT