- Conditions
- Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic Analysis
- Interventions
- Metformin, Dietary Modification
- Drug · Behavioral
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 11 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
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Showing 1–6
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- Conditions
- Obesity, Glucose Intolerance, Diabetes, Acanthosis Nigricans
- Interventions
- Not listed
- Lead sponsor
- National Center for Research Resources (NCRR)
- NIH
- Eligibility
- 8 Years to 18 Years
- Healthy volunteers
- Accepts healthy volunteers
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Obesity, Acanthosis Nigricans, Central Obesity
- Interventions
- CHL program, Delayed Optimized CHL program
- Other
- Lead sponsor
- University of Hawaii
- Other
- Eligibility
- 2 Years to 8 Years
- Enrollment
- 9,840 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2020
- U.S. locations
- 1
- States / cities
- Honolulu, Hawaii
- Conditions
- Diabetes Mellitus
- Interventions
- Metformin, Placebo
- Drug
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 10 Years to 20 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Acanthosis Nigricans
- Interventions
- Sirolimus 0.2%
- Drug
- Lead sponsor
- Narrows Institute for Biomedical Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Severe Insulin Resistance
- Interventions
- Metreleptin
- Drug
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 5 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2030
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland