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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Accident Injury Clear all
Completed No phase listed Observational

Inflammation and the Host Response to Injury (Trauma)

NCT00257231
View directory record Official record
Conditions
Trauma, Burns, Multiple Organ Failure
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years and older
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2018
U.S. locations
4
States / cities
Denver, Colorado • Pittsburgh, Pennsylvania • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT03353246
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational

Evaluation of Biomarker Kinetics After Mild Brain Injury Trauma

NCT02541123
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Blood draw
Other
Lead sponsor
Banyan Biomarkers, Inc
Industry
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
7
States / cities
Gainesville, Florida • Orlando, Florida • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Jul 24, 2026, 8:34 AM EDT
Not yet recruiting Not applicable Interventional

Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress

NCT07634419
View directory record Official record
Conditions
Critical Illness, Heart Failure, Sepsis, Ards, Pneumonia, Trauma Injury
Interventions
Lift mobile mindfulness, Enlighten Recovery education program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
3
States / cities
Los Angeles, California • Durham, North Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists

NCT06851234
View directory record Official record
Conditions
Head Injury Trauma
Interventions
osteopathic manipulative medicine, The sham light touch will be performed by an investigator not trained in bodywork or a first--year osteopathic medical student.
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 50 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Greenvale, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Active, not recruiting No phase listed Observational

Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure

NCT04313712
View directory record Official record
Conditions
Blast or Combat Exposure, Head Injury Trauma
Interventions
ibogaine with magnesium treatment
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational Results available

ICG Fluorescence Imaging in Lower Extremity Amputation Patients

NCT04250558
View directory record Official record
Conditions
Trauma Injury
Interventions
Lower Extremity Amputation
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using mHealth to Improve Emotional Recovery After Pediatric Injury

NCT04579198
View directory record Official record
Conditions
Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed Not applicable Interventional

EMDR vs. PC For Motor Vehicle Accident Trauma

NCT03271359
View directory record Official record
Conditions
Trauma, Psychological, Motor Vehicle Accident
Interventions
EMDR, PC
Behavioral
Lead sponsor
Trauma Institute & Child Trauma Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Northampton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 6, 2017 · Synced Jul 24, 2026, 8:34 AM EDT
Enrolling by invitation Phase 4 Interventional

PPP Versus Corticosteroid for Thigh Muscle Injuries

NCT07513142
View directory record Official record
Conditions
Thigh Muscle Injury, Thigh Injury, Musculoskeletal, Musculoskeletal Injury Trauma, Musculoskeletal Injuries
Interventions
Corticosteroid, Platelet Poor Plasma
Drug · Biological
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
15 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Promoting Recovery After Brain Injury Using Focused Ultrasound

NCT07277309
View directory record Official record
Conditions
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Interventions
Low-intensity focused ultrasound
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional

Comparative Utility of Clinical Balance Measures in Traumatic Brain Injury

NCT02696538
View directory record Official record
Conditions
Traumatic Brain Injury, Acquired Brain Injury, Accidental Falls
Interventions
Functional Gait Assessment, mini-Balance Evaluation Systems Test, Berg Balance Scale
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed Phase 4 Interventional

Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures

NCT03574376
View directory record Official record
Conditions
Trauma, Trauma Injury, Pain, Acute
Interventions
Bupivacaine Liposome Injection, Bupivacaine
Drug
Lead sponsor
Chadrick Evans
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Jul 24, 2026, 8:34 AM EDT
Enrolling by invitation Phase 4 Interventional

Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia

NCT05091905
View directory record Official record
Conditions
Pain, Acute Postoperative, Trauma Injury
Interventions
Continuous Infusion of ropivacaine 0.2%, Titratable Automated Intermittent Boluses of ropivacaine 0.2%
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

NCT04530955
View directory record Official record
Conditions
Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis), Muscle Spasticity, Cerebral Palsy, Spastic
Interventions
Prometra II Programmable Pump - Flowonix Medical
Device
Lead sponsor
Culicchia Neurological Clinic
Other
Eligibility
22 Years to 85 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Tourniquet Training Effectiveness Study

NCT03538379
View directory record Official record
Conditions
Trauma Injury, Hemorrhage
Interventions
Bleeding Control Basic (B-Con) Course
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2018 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting No phase listed Observational

The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

NCT06606119
View directory record Official record
Conditions
Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia
Interventions
Data and tissue collection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Phase 3 Interventional Results available

Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation

NCT04704869
View directory record Official record
Conditions
Trauma Injury
Interventions
Cryoprecipitate, Red Blood Cells, Plasma, Platelets, Whole Blood
Biological
Lead sponsor
Bryan Cotton
Other
Eligibility
16 Years and older
Enrollment
1,604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Active, not recruiting No phase listed Observational

ICG Fluorescence Imaging in Open Fracture Trauma Patients

NCT04416412
View directory record Official record
Conditions
Trauma Injury
Interventions
Immunofluorescence Imaging
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
4
States / cities
Irvine, California • Baltimore, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

NCT05357170
View directory record Official record
Conditions
Sepsis, Trauma Injury
Interventions
Human feces collection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 110 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Enrolling by invitation Not applicable Interventional

Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications

NCT06304428
View directory record Official record
Conditions
Accidental Falls/Prevention and Control, Osteoporosis
Interventions
Deprescribing Care Model, Bone Health Service Model, Injury Prevention Service Model
Other
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
3,780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational

Concussion in Motor Vehicle Accidents: The Concussion Identification Index

NCT02858544
View directory record Official record
Conditions
Motor Vehicle Accidents, TBI (Traumatic Brain Injury), Brain Contusion, Brain Injuries, Cortical Contusion, Concussion Mild, Cerebral Concussion, Brain Concussion, Accidents, Traffic, Traffic Accidents, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With no Loss of Consciousness, Traumatic Brain Injury With Loss of Consciousness
Interventions
The Concussion Identification Index, ImPACT
Other
Lead sponsor
Clionsky Neuro Systems Inc.
Industry
Eligibility
10 Years to 60 Years
Enrollment
1,790 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2016 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Ultrasound Stimulation for Patients in a Disorder of Consciousness

NCT06939348
View directory record Official record
Conditions
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Interventions
The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain.
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Los Angeles, California • Pomona, California • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational

SFDI in High Energy Lower Extremity Fracture

NCT05635617
View directory record Official record
Conditions
Trauma Injury
Interventions
Lower Extremity Surgery
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Jul 24, 2026, 8:34 AM EDT