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ClinicalTrials.gov public records Last synced Oct 29, 2026, 6:08 PM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Acellular Dermal Matrix Clear all
Terminated Not applicable Interventional Results available

Use of Dermal Matrix in Breast Reconstruction

NCT00692692
View directory record Official record
Conditions
Breast Cancer
Interventions
DermaMatrix, standard of care tissue expander breast reconstruction surgery after mastectomy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Oct 29, 2026, 6:08 PM EDT
Recruiting No phase listed Observational

AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction

NCT06512259
View directory record Official record
Conditions
Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Interventions
AlloMend® Acellular Dermal Matrix allograft
Other
Lead sponsor
AlloSource
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional

Comparing AlloDerm and DermACELL in Breast Reconstruction

NCT04710537
View directory record Official record
Conditions
Acellular Dermal Matrix in Breast Reconstruction
Interventions
AlloDerm, DermACELL
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®

NCT00881959
View directory record Official record
Conditions
Gingival Recession
Interventions
Puros® Dermis versus Alloderm®
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
4
States / cities
Birmingham, Alabama • Ann Arbor, Michigan • Newark, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

NCT05565079
View directory record Official record
Conditions
Recession, Gingival
Interventions
Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix
Biological
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Active, not recruiting Phase 3 Interventional

A Study of the Use of Acellular Dermal Matrix for Breast Reconstruction

NCT05316324
View directory record Official record
Conditions
Breast Cancer
Interventions
Prepectoral Breast Reconstruction with Acellular Dermal Matrix (ADM), Prepectoral Breast Reconstruction without Acellular Dermal Matrix (ADM)
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
New York, New York • Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implant Placement With Simultaneous Gum Grafting

NCT01431144
View directory record Official record
Conditions
Edentulous
Interventions
connective tissue autograft, connective tissue allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 29, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spacer Graft Study

NCT04140734
View directory record Official record
Conditions
Eyelid Diseases, Eyelid Droop
Interventions
Spacer Graft
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

NCT04920136
View directory record Official record
Conditions
Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa, Thin Gingiva
Interventions
Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM), Free Gingival graft
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Terminated Phase 4 Interventional

The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction

NCT00616824
View directory record Official record
Conditions
Mastectomy, Postoperative Pain, Complications
Interventions
Dermamatrix to cover lateral aspect of tissue expander, Serratus anterior to cover lateral aspect of tissue expander
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft

NCT02139748
View directory record Official record
Conditions
Dental Implants
Interventions
Dental Implant & ADM, Dental Implant & ADM & bone xenograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implant Placement and Simultaneous Soft Tissue Grafting With Single or Double Layers of Acellular Dermal Matrix

NCT01902056
View directory record Official record
Conditions
Clinical Efficacy
Interventions
One layer allograft, Two layer allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 17, 2013 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous

NCT03582995
View directory record Official record
Conditions
Recession, Gingival
Interventions
Flap Surgery for root coverage with Alloderm and xenograft, Tunnel Surgery for root coverage with Alloderm and xenograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 29, 2026, 6:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Root Coverage Comparing an Allograft to a Bovine Xenograft

NCT02810067
View directory record Official record
Conditions
Gingival Recession
Interventions
Tunnel + AlloDerm, Tunnel + Novomatrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Phase 4 Interventional

Ridge Preservation Comparing a Polylactic Acid Membrane vs. an Acellular Dermal Matrix Membrane

NCT02152215
View directory record Official record
Conditions
Ridge Preservation
Interventions
Acellular dermal matrix membrane, Polylactic acid membrane
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 29, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acellular Dermal Matrix Investigation in Breast Reconstruction

NCT06456554
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Acellular Dermal Matrix (Cortiva Tissue Matrix)
Device
Lead sponsor
RTI Surgical
Industry
Eligibility
22 Years and older · Female only
Enrollment
467 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
13
States / cities
Little Rock, Arkansas • Duarte, California • Aurora, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional

Implant Phenotype Modification Via GBR and ADM

NCT07082244
View directory record Official record
Conditions
Horizontal Ridge Deficiency
Interventions
Dental implant placement, Guided bone regeneration with collagen membrane, Guided bone regeneration with acellular dermal matrix.
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction

NCT02228889
View directory record Official record
Conditions
Hernia, Ventral, Intestinal Fistula, Fibromatosis, Abdominal
Interventions
Abdominal wall reconstruction with Strattice, Assess pain intensity at last office visit preoperatively, Assess pain interference at last office visit preoperatively, Assess physical functioning at last office visit preoperatively, Assess patient quality of life at last office visit preoperatively, Assess patient pain intensity postoperatively, Assess pain interference postoperatively, Assess physical functioning postoperatively, Assess quality of life postoperatively, Assess hernia recurrence at 30 days postoperatively, Assess bulge at 30 days postoperatively, Assess Surgical Site Occurrences at 30 days postoperatively, Assess hernia recurrence at 1 year postoperatively, Assess bulge at 1 year postoperatively, Assess Surgical Site Occurrences at 1 year postoperatively, Assess overall complications at 30 days postoperatively, Assess overall complications at 1 year postoperatively, Abdominal wall reconstruction with XenMatrix, Strattice, XenMatrix
Procedure · Other · Device
Lead sponsor
Jeffrey Janis
Other
Eligibility
18 Years to 99 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Phase 2 Interventional

Compare Outcomes Between Two Acellular Dermal Matrices

NCT02891759
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm RTU, Cortiva 1mm Allograft Dermis, Skin or nipple-sparing mastectomy, Breast Q, Surgery
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
22 Years to 70 Years · Female only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Cosmetic Result/Toxicity in Post-Mastectomy Immediate Reconstruction Expander+RT

NCT01664091
View directory record Official record
Conditions
Breast Cancer
Interventions
post-mastectomy radiation therapy (PMRT), tissue expander (TE), acellular dermal matrix (ADM)
Radiation · Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 26, 2019 · Synced Oct 29, 2026, 6:08 PM EDT
Not listed Not applicable Interventional

Dermacell ADM Without Basement Membrane

NCT03667560
View directory record Official record
Conditions
Breast Cancer
Interventions
Dermacell ADM without basement membrane, FlexHD
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 29, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

NCT01353495
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
APM Graft (BIOTAPE XMTM), Wound Debridement
Device · Other
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Fresno, California • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 29, 2026, 6:08 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants

NCT07512245
View directory record Official record
Conditions
Acellular Dermal Matrix, Alveolar Mucosa
Interventions
Phase I dental implant placement with acellular dermis, Phase II dental implant uncovery with acellular dermis
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 29, 2026, 6:08 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Clinical Trial Testing Root Coverage With Acellular Dermal Matrix in Thin and Thick Gingival Biotypes

NCT03057730
View directory record Official record
Conditions
Gingival Recession
Interventions
Acellular Dermal Matrix
Biological
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 29, 2026, 6:08 PM EDT