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ClinicalTrials.gov public records Last synced Sep 3, 2026, 12:52 PM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Active Surveillance for Prostate Cancer Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners

NCT03575832
View directory record Official record
Conditions
Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
Interventions
Counseling, Informational Intervention, Quality-of-Life Assessment, Questionnaire Administration, Telephone-Based Intervention
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting No phase listed Observational

A Study of Telemedicine Shared Medical Appointments (SMAs) Versus Individual Telemedicine Visits for People With Prostate Cancer

NCT05416996
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Phase 2 Interventional

Carbohydrate Restricted Diet Intervention for Men on Prostate Cancer Active Surveillance

NCT03679260
View directory record Official record
Conditions
Prostate Cancer
Interventions
Carbohydrate restricted diet, Non-restricted diet, Phone counseling with dietitian
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Sep 3, 2026, 12:52 PM EDT
Recruiting No phase listed Observational

Active Surveillance for Cancer of the Prostate (ASCaP)

NCT00949819
View directory record Official record
Conditions
Prostate Cancer
Interventions
Active surveillance
Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
30 Years to 85 Years · Male only
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Completed No phase listed Observational

Ketogenic Diet and Prostate Cancer Surveillance Pilot

NCT03194516
View directory record Official record
Conditions
Prostate Cancer
Interventions
Surveillance
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 3, 2026, 12:52 PM EDT
Suspended Phase 2 Interventional

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

NCT04519879
View directory record Official record
Conditions
Prostate Adenocarcinoma, PSA Failure, PSA Progression, Recurrent Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
Interventions
Clinical Observation, Patient Observation, Questionnaire Administration, White Button Mushroom Extract
Other · Drug
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Duarte, California • Glendora, California • Irvine, California + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Phase 3 Interventional Results available

Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer

NCT03686683
View directory record Official record
Conditions
Adenocarcinoma of the Prostate
Interventions
sipuleucel-T
Biological
Lead sponsor
Dendreon
Industry
Eligibility
18 Years and older · Male only
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
56
States / cities
Gilbert, Arizona • Tucson, Arizona • Little Rock, Arkansas + 47 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting Not applicable Interventional

Surveillance or Focal Therapy

NCT07207902
View directory record Official record
Conditions
Prostate Cancer
Interventions
Explainer video
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 3, 2026, 12:52 PM EDT
Recruiting No phase listed Observational

Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Cognitive and Usability Testing

NCT05497024
View directory record Official record
Conditions
Prostate Cancer
Interventions
Interviews, Surveys
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
65 Years and older · Male only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting Phase 2 Interventional

To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

NCT04597359
View directory record Official record
Conditions
Prostate Carcinoma
Interventions
Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration, Sinecatechins
Drug · Other
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
21 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
345
States / cities
Fairbanks, Alaska • Phoenix, Arizona • Fayetteville, Arkansas + 224 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Recruiting Not applicable Interventional

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

NCT04692675
View directory record Official record
Conditions
Prostate Cancer
Interventions
mpMRI
Diagnostic Test
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Male only
Enrollment
508 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Terminated No phase listed Observational

Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate Cancer

NCT02139774
View directory record Official record
Conditions
Prostate Cancer
Interventions
Walk with Ease
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
65 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Phase 3 Interventional Results available

Prostate Cancer Intervention Versus Observation Trial (PIVOT)

NCT00007644
View directory record Official record
Conditions
Prostate Cancer
Interventions
Radical prostatectomy
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 75 Years · Male only
Enrollment
731 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2010
U.S. locations
31
States / cities
Birmingham, Alabama • North Little Rock, Arkansas • Long Beach, California + 28 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2020 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting Phase 2 Interventional

Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)

NCT02768363
View directory record Official record
Conditions
Prostate Cancer
Interventions
aglatimagene besadenovec, placebo, valacyclovir
Biological · Drug
Lead sponsor
Candel Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
22
States / cities
Golden, Colorado • Chicago, Illinois • New Orleans, Louisiana + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 3, 2026, 12:52 PM EDT
Not yet recruiting Not applicable Interventional

WATER IV PCa (AS Sub-study)

NCT07650448
View directory record Official record
Conditions
Localized Prostate Cancer
Interventions
Aquablation Therapy, Active Surveillance
Device · Other
Lead sponsor
PROCEPT BioRobotics
Industry
Eligibility
45 Years and older · Male only
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2038
U.S. locations
24
States / cities
Chandler, Arizona • Los Angeles, California • Murrieta, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting Not applicable Interventional

Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

NCT02176902
View directory record Official record
Conditions
Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions
behavioral dietary intervention, omega-3 fatty acid, laboratory biomarker analysis
Behavioral · Dietary Supplement · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 3, 2026, 12:52 PM EDT
Active, not recruiting Not applicable Interventional

Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer

NCT04396808
View directory record Official record
Conditions
Prostate Cancer
Interventions
Decipher, Prolaris, Oncotype Dx Genomic Prostate Score (GPS), Standard of care (askMUSIC score)
Device · Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
805 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2031
U.S. locations
8
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Grand Rapids, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 3, 2026, 12:52 PM EDT
Completed No phase listed Observational

Prospective Observation Study of Insulin Sensitivity During and After Gonadotropin Releasing Hormone Agonist Therapy for Prostate Cancer

NCT00456144
View directory record Official record
Conditions
Prostate Cancer
Interventions
Gonadotropin Releasing Hormone Agonist Therapy
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Not applicable Interventional

Active Surveillance Exercise Clinical Trial

NCT02435472
View directory record Official record
Conditions
Localized Prostate Cancer, Active Surveillance for Prostate Cancer
Interventions
Exercise, Cardiopulmonary Exercise Test (CPET)
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Not applicable Interventional Results available

MRI Based Active Selection for Treatment Trial

NCT02242773
View directory record Official record
Conditions
Prostate Cancer
Interventions
Multi-Parametric MRI, MRI-Guided Biopsy
Device
Lead sponsor
University of Miami
Other
Eligibility
35 Years to 85 Years · Male only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Phase 4 Interventional Results available

Assessment Of Dutasteride (AVODART) In Extending The Time To Progression Of Low-Risk, Localized Prostate Cancer In Men

NCT00363311
View directory record Official record
Conditions
Neoplasms, Prostate
Interventions
Dutasteride, Matching placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
50 Years to 80 Years · Male only
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
58
States / cities
Little Rock, Arkansas • Beverly Hills, California • Laguna Hills, California + 54 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2017 · Synced Sep 3, 2026, 12:52 PM EDT
Withdrawn Not applicable Interventional

Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer

NCT03823001
View directory record Official record
Conditions
Prostate Cancer
Interventions
virtual biopsy (VB) monitoring protocol
Diagnostic Test
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Sep 3, 2026, 12:52 PM EDT
Completed Not applicable Interventional

Devel. and Eval. of an Active Surveillance Decision Aid for Men With Low or Intermediate Grade Prostate Cancer

NCT02342626
View directory record Official record
Conditions
Adenocarcinoma of Prostate
Interventions
Dashboard
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
40 Years to 85 Years · Male only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Sep 3, 2026, 12:52 PM EDT
Recruiting No phase listed Observational

Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Efficacy Testing

NCT06785441
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
65 Years and older · Male only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Sep 3, 2026, 12:52 PM EDT