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ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:12 PM EDT

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Showing 1–24 of 74 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Acute Back Pain Clear all
Completed Phase 3 Interventional Results available

Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

NCT00671879
View directory record Official record
Conditions
Lower Back Pain
Interventions
Carisoprodol SR 700 mg, Carisoprodol SR 500 mg, Placebo
Drug
Lead sponsor
Meda Pharmaceuticals
Industry
Eligibility
18 Years to 70 Years
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
73
States / cities
Birmingham, Alabama • Gulf Shores, Alabama • Hueytown, Alabama + 62 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2012 · Synced Oct 17, 2026, 10:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

NCT05721027
View directory record Official record
Conditions
Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
Interventions
Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
Drug · Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 17, 2026, 10:12 PM EDT
Recruiting Phase 4 Interventional

Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department

NCT06395428
View directory record Official record
Conditions
Back Pain, Chronic Pain
Interventions
Haloperidol, Ketorolac Tromethamine
Drug
Lead sponsor
Western Michigan University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

Usability of a Multimodal External Neuromodulatory Device to Relieve Acute Low Back Pain

NCT04494841
View directory record Official record
Conditions
Low Back Pain, Low Back Sprain, Low Back Pain, Recurrent
Interventions
Duotherm VibraCool Back Device
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 21, 2022 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Tolperisone in Acute Muscle Spasm of the Back

NCT03802565
View directory record Official record
Conditions
Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain, Muscle Cramp, Muscle Spasm, Low Back Pain
Interventions
Tolperisone, Placebo
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
43
States / cities
Huntsville, Alabama • Tempe, Arizona • Little Rock, Arkansas + 39 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

CAFE Study - Cancer Patient Fracture Evaluation

NCT00211237
View directory record Official record
Conditions
Cancer, Spinal Fractures
Interventions
Balloon Kyphoplasty, Non Surgical Management
Device · Other
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
9
States / cities
Escondido, California • Boulder, Colorado • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 17, 2026, 10:12 PM EDT
Terminated Not applicable Interventional

Intracutaneous Sterile Water Injections for Acute Low Back Pain in the Emergency Department

NCT04240483
View directory record Official record
Conditions
Low Back Pain
Interventions
Intracutaneous sterile water injections (ISWI) group, Intracutaneous dry injections (IDI) group
Other
Lead sponsor
Lindsey schmelzer
Federal
Eligibility
18 Years to 64 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 17, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional

Battlefield Acupressure for Acute Back Pain Management in the Emergency Department

NCT07771686
View directory record Official record
Conditions
Acute Back Pain
Interventions
Battlefield auricular acupressure, Sham
Procedure
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms

NCT00817986
View directory record Official record
Conditions
Back Pain
Interventions
Arbaclofen placarbil, 20 mg, Placebo, Arbaclofen placarbil, 30 mg, Arbaclofen placarbil, 40 mg
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
20
States / cities
Litchfield Park, Arizona • Anaheim, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 4 Interventional

FREE Study - Fracture Reduction Evaluation

NCT00211211
View directory record Official record
Conditions
Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
Interventions
Balloon Kyphoplasty
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Results available

A Randomized Study of Three Medication Regimens for Acute Low Back Pain

NCT01587274
View directory record Official record
Conditions
Acute Low Back Pain
Interventions
Naproxen, Cyclobenzaprine, Oxycodone/ acetaminophen
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
21 Years to 64 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Not applicable Interventional

Effects of a Lower Back Wrap Device on Lower Back Pain, Physical Function, and Quality of Life

NCT06749912
View directory record Official record
Conditions
Lower Back Pain, Lower Back Pain Chronic, Acute Low Back Pain
Interventions
Low back pain wrap
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
20 Years to 65 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 17, 2026, 10:12 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study

NCT01794988
View directory record Official record
Conditions
Chronic Pain
Interventions
Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response, NO TIVR
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 20, 2013 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 3 Interventional

Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain

NCT01968005
View directory record Official record
Conditions
Low Back Pain
Interventions
Etoreat®(Etodolac-Lidocaine Topical Patch), Placebo
Drug
Lead sponsor
MEDRx USA, Inc.
Industry
Eligibility
14 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
7
States / cities
Carlsbad, California • Miami, Florida • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica

NCT00668434
View directory record Official record
Conditions
Sciatica
Interventions
Prednisone, Placebo
Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 70 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Redwood City, California • Roseville, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 17, 2026, 10:12 PM EDT
Completed No phase listed Observational

Blood Sample Donations to Study the Role of Genes in Pain

NCT00341367
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
Not listed
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
1
States / cities
South Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 17, 2026, 10:12 PM EDT
Completed No phase listed Observational

Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care

NCT05254470
View directory record Official record
Conditions
Musculoskeletal Injury, Pain, Chronic, Pain, Acute, Sport Injury, Soft Tissue Injuries, Arm Injury, Back Pain, Tendon Injuries, Muscle Injury
Interventions
Continuous Ultrasound
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fairfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 17, 2026, 10:12 PM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Acute Low Back Pain Management

NCT01726803
View directory record Official record
Conditions
Low Back Pain
Interventions
Early Physical Therapy with Usual Care, Usual Care
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Results available

Effect of L-dopa In Subacute Back Pain Population

NCT01951105
View directory record Official record
Conditions
Sub-acute Back Pain
Interventions
Naproxen, Carbidopa/Levodopa, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of SP-103 in Subjects With Moderate to Severe Acute Lower Back Pain

NCT05096494
View directory record Official record
Conditions
Moderate to Severe Acute Lower Back Pain
Interventions
SP-103, Placebo
Drug
Lead sponsor
Scilex Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Phoenix, Arizona • Fernandina Beach, Florida • Jacksonville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 2 Interventional

Psychosocial Treatment for Acute Low Back Pain

NCT00000418
View directory record Official record
Conditions
Acute Low Back Pain
Interventions
Psychosocial intervention
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1977 – 2001
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 6, 2013 · Synced Oct 17, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Results available

Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.

NCT04611529
View directory record Official record
Conditions
Low Back Pain
Interventions
Ibuprofen 400 mg, Topical diclofenac
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 17, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Investigating Medical Massage Therapy for Patients With Sub-Acute Lower Back Pain

NCT07615816
View directory record Official record
Conditions
Lower Back Pain, Subacute Lower Back Pain, Medical Massage Therapy
Interventions
Medical Massage Therapy, Provider Directed Care
Procedure · Other
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Joint Base Lewis McChord, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 17, 2026, 10:12 PM EDT