- Conditions
- Heart Disease, Heart Failure With Preserved Ejection Fraction, Exercise Intolerance, Pulmonary Hypertension
- Interventions
- Nitrite, Saline Placebo for Nitrite
- Drug
- Lead sponsor
- Barry Borlaug
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
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Showing 1–24
of 254
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Acute Heart Failure
- Interventions
- Placebo, Nesiritide, Dopamine
- Other · Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 7
- States / cities
- Boston, Massachusetts • Minneapolis, Minnesota • Rochester, Minnesota + 4 more
- Conditions
- Acute Heart Failure
- Interventions
- Serelaxin
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- Up to 17 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 5
- States / cities
- Denver, Colorado • St Louis, Missouri • The Bronx, New York + 2 more
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards, Pneumonia, Trauma Injury
- Interventions
- Lift mobile mindfulness, Enlighten Recovery education program
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2031
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Durham, North Carolina • Charleston, South Carolina
- Conditions
- Congestive Heart Failure, Non-ischemic Cardiomyopathy
- Interventions
- Triheptanoin oil
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Acute Heart Failure, Decompensated Heart Failure
- Interventions
- subcutaneous furosemide and sc2wear device
- Combination Product
- Lead sponsor
- Adrian Hernandez
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 16
- States / cities
- Atlanta, Georgia • Chicago, Illinois • Baltimore, Maryland + 8 more
- Conditions
- Heart Failure
- Interventions
- Tolvaptan, Furosemide
- Drug
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 2
- States / cities
- Los Angeles, California
- Conditions
- Type 2 Diabetes, Heart Failure, Reduced Ejection Fraction
- Interventions
- Ketone Monoester (KE)
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Spironolactone and patiromer
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Acute Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Heart Failure
- Interventions
- Cardiac rehab
- Other
- Lead sponsor
- Sanford Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Sioux Falls, South Dakota
- Conditions
- Drug Use, Alcohol Use, Congestive Heart Failure, Pneumonia, Acute Myocardial Infarction, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, End-Stage Renal Disease
- Interventions
- Specialized Community Disease Management, Treatment As Usual
- Behavioral
- Lead sponsor
- Treatment Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 97 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Cardiorenal Syndrome
- Interventions
- Milrinone, Dobutamine
- Drug
- Lead sponsor
- Maimonides Medical Center
- Other
- Eligibility
- 18 Years to 95 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Heart Failure, Acute Kidney Injury
- Interventions
- Dapagliflozin 10mg Tab, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Ularitide, Placebo
- Drug
- Lead sponsor
- Cardiorentis
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 2,157 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 39
- States / cities
- Huntsville, Alabama • Montgomery, Alabama • Sacramento, California + 34 more
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- High-dose furosemide, Low-dose furosemide, Low-dose furosemide combined with low-dose dopamine
- Drug
- Lead sponsor
- Larissa University Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 161 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • Cleveland, Ohio
- Conditions
- Renal Insufficiency, Congestive Heart Failure
- Interventions
- tonapofylline, Placebo
- Drug
- Lead sponsor
- Biogen
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 420 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 68
- States / cities
- Huntsville, Alabama • Mobile, Alabama • Fort Smith, Arkansas + 64 more
- Conditions
- Heart Failure
- Interventions
- Comprehensive ED heart failure management tool
- Other
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17,459 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 21
- States / cities
- Antioch, California • Fremont, California • Fresno, California + 17 more
- Conditions
- Heart Failure, Congestive
- Interventions
- ZP120, I.v. catherization, 6-minutes walk performance, Dyspnea severity assessment, Blood sampling for laboratory tests, ECG, Physical examination
- Drug · Procedure · Behavioral
- Lead sponsor
- Zealand Pharma
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 22
- States / cities
- Los Angeles, California • San Diego, California • San Francisco, California + 17 more
- Conditions
- Cardiogenic Shock
- Interventions
- Vasopressor, Inotrope, Acute Mechanical Circulatory Support Devices
- Drug · Device
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2026
- U.S. locations
- 16
- States / cities
- Weston, Florida • Chicago, Illinois • Portland, Maine + 10 more
- Conditions
- Myocardial Infarction
- Interventions
- Provacel, Placebo
- Biological
- Lead sponsor
- Mesoblast, Inc.
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 15
- States / cities
- Phoenix, Arizona • San Diego, California • Washington D.C., District of Columbia + 12 more
- Conditions
- Heart Decompensation
- Interventions
- Non-Interventional
- Other
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Princeton, New Jersey
- Conditions
- Heart Failure, Respiratory Insufficiency, Stroke Acute, Infectious Diseases, Rheumatic Diseases
- Interventions
- Rivaroxaban, 10 mg, Rivaroxaban, 7.5 mg, Placebo
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 12,024 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 135
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Sheffield, Alabama + 132 more
- Conditions
- Heart Failure, Congestive
- Interventions
- Continuous Aortic Flow Augmentation
- Device
- Lead sponsor
- Orqis Medical Corporation
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 1
- States / cities
- San Diego, California