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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:57 AM EDT

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Showing 145–168 of 360 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Acute Cardiac Syndrome Clear all
Active, not recruiting Not applicable Interventional

Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)

NCT05649384
View directory record Official record
Conditions
Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI
Interventions
European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm
Diagnostic Test
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older
Enrollment
64,374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Results available

Intravenous Exenatide in Coronary Intensive Care Unit (ICU) Patients

NCT00736229
View directory record Official record
Conditions
Hyperglycemia, Acute Coronary Syndromes, Myocardial Infarction
Interventions
Exenatide
Drug
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational

ECG Methods for the Prompt Identification of Coronary Events

NCT04237688
View directory record Official record
Conditions
Chest Pain, Myocardial Infarction, Myocardial Ischemia, Acute Coronary Syndrome
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 5, 2026, 4:57 AM EDT
Withdrawn Phase 2 Interventional

A Safety and Efficacy Trial Evaluating the Use of Fondaparinux in Percutaneous Coronary Intervention (PCI)(63133)(WITHDRAWN)

NCT00060554
View directory record Official record
Conditions
Myocardial Infarction, Coronary Disease
Interventions
fondaparinux sodium, heparin, percutaneous coronary intervention (PCI)
Drug · Procedure
Lead sponsor
Schering-Plough
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
8
States / cities
Ocala, Florida • Chicago, Illinois • Worcester, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2009 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Results available

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects

NCT00699998
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Clopidogrel, Prasugrel, Commercially-available Aspirin
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
9,326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
165
States / cities
Birmingham, Alabama • Huntsville, Alabama • Glendale, Arizona + 162 more
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Telehealth Group Counseling and Preventive Care for Women

NCT06404515
View directory record Official record
Conditions
ASCVD, NSTEMI, STEMI, Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina, Chest Pain
Interventions
Telehealth Group Counseling
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation

NCT03746782
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Flow Cytrometry; Thrombin Generation Assay
Diagnostic Test
Lead sponsor
CirQuest Labs, LLC
Other
Eligibility
18 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 23, 2020 · Synced Oct 5, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional

Positive Emotions Following Acute Cardiac Events

NCT05412862
View directory record Official record
Conditions
Acute Coronary Syndrome, Physical Inactivity
Interventions
Positive Psychology + Motivational Interviewing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 95 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 2 Interventional Results available

Polypill in Acute Coronary Syndrome

NCT05514938
View directory record Official record
Conditions
Acute Coronary Syndrome, Lipid Disorder, Coronary Artery Disease
Interventions
Polypill, Usual Care (individual medications prescribed by primary cardiologist)
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Results available

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

NCT00658515
View directory record Official record
Conditions
Coronary Heart Disease
Interventions
Dalcetrapib (RO4607381), Evidence-based medical care for Acute Coronary Syndrome, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
45 Years and older
Enrollment
15,871 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
513
States / cities
Birmingham, Alabama • Mobile, Alabama • Tuscaloosa, Alabama + 400 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2020 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 2 Interventional Results available

Safety of PZ-128 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention

NCT02561000
View directory record Official record
Conditions
Arterial Occlusive Diseases, Coronary Artery Disease, Coronary Disease, Arteriosclerosis, Heart Diseases, Myocardial Ischemia, Vascular Diseases, Acute Coronary Syndrome
Interventions
PZ-128, Placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • Worcester, Massachusetts • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 5, 2026, 4:57 AM EDT
Terminated Not applicable Interventional

Smartphone GUIded MeDication AdherencE and Rehabilitation in Patients With Coronary Artery Disease

NCT03207646
View directory record Official record
Conditions
Coronary Artery Disease, Acute Coronary Syndrome
Interventions
BrightHeart®
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Oct 5, 2026, 4:57 AM EDT
Terminated Phase 3 Interventional

VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome

NCT01130246
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
A-002, varespladib methyl, Placebo
Drug
Lead sponsor
Anthera Pharmaceuticals
Industry
Eligibility
40 Years and older
Enrollment
5,189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
83
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 67 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2012 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study

NCT01407146
View directory record Official record
Conditions
Acute Myocardial Infarction, Heart Attack, Acute Coronary Syndrome, Unstable Angina
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
2,381 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Anakinra in Infants and Children With Coronary Artery Abnormalities in Acute Kawasaki Disease

NCT02179853
View directory record Official record
Conditions
Kawasaki Disease
Interventions
Anakinra
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
1 Month to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

NCT03118752
View directory record Official record
Conditions
Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions
Collaborative Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • Salem, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational Results available

ClearWay Rx Readmission Registry

NCT01673893
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
ClearWay™ Rx catheter
Device
Lead sponsor
Cardiovascular Institute of the South Clinical Research Corporation
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Lafayette, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Results available

IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.

NCT00091507
View directory record Official record
Conditions
Angina, Unstable, Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction, Heart Failure, Congestive
Interventions
GIK, Placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
30 Years and older
Enrollment
911 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
13
States / cities
Anchorage, Alaska • New Haven, Connecticut • Macon, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Oct 5, 2026, 4:57 AM EDT
Terminated Phase 4 Interventional Results available

Effects of Atorvastatin on Myonecrosis

NCT00344019
View directory record Official record
Conditions
Coronary Disease
Interventions
Placebo Oral Tablet, Atorvastatin 80mg, Screening
Drug · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational

Investigation of the Biomarker Copeptin in Patients With Acute Myocardial Infarction

NCT00952744
View directory record Official record
Conditions
Acute Coronary Syndromes
Interventions
Not listed
Lead sponsor
Brahms AG
Industry
Eligibility
18 Years and older
Enrollment
2,071 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
11
States / cities
Palo Alto, California • San Diego, California • San Francisco, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2012 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention

NCT00413309
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Video Capsule Endoscopy
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2009 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational

Acute Coronary Syndrome CardioFlux TM Study (ACCMED)

NCT04739267
View directory record Official record
Conditions
Acute Myocardial Injuries
Interventions
CardioFlux
Device
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
390 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 5, 2026, 4:57 AM EDT
Completed No phase listed Observational

Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)

NCT00922662
View directory record Official record
Conditions
Acute Coronary Syndrome, Chest Pain
Interventions
Not listed
Lead sponsor
Kavitha Chinnaiyan
Other
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2016 · Synced Oct 5, 2026, 4:57 AM EDT
Completed Phase 2 Interventional

Online Tai Chi Plus Fitbit After ACS

NCT05699642
View directory record Official record
Conditions
Acute Coronary Syndrome, Physical Inactivity
Interventions
Tai chi + wearable
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 5, 2026, 4:57 AM EDT