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ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Acute Confusional State Clear all
Active, not recruiting No phase listed Observational

AKI and Delirium Risk Prediction and Cost Burden Study

NCT07866560
View directory record Official record
Conditions
Acute Kidney Injury, Delirium
Interventions
It is observational trial with no intervention being evaluated
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
25,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 3 Interventional

Trial of Safety Nets In Hospitalized Patients

NCT00409370
View directory record Official record
Conditions
Delirium, Agitated Behavior, Alcohol Withdrawl, Acute Confusional State, Acute Psychosis
Interventions
SOMA safe enclosure
Device
Lead sponsor
Griffin Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 8, 2006 · Synced Oct 24, 2026, 9:46 AM EDT
Suspended Not applicable Interventional

Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks

NCT06038136
View directory record Official record
Conditions
Stroke, Acute, Stroke, Ischemic, Delirium, Neuro: Cerebrovascular Accident
Interventions
Decreased Neuro Checks overnight
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Completed No phase listed Observational

A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg

NCT02921828
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Not listed
Lead sponsor
Celgene
Industry
Eligibility
18 Years and older
Enrollment
1,149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
No City Provided, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 24, 2026, 9:46 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

NCT07293078
View directory record Official record
Conditions
Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure, Acute Kidney Injury, Delirium Confusional State, Shock
Interventions
Point-of-care large language model decision support (ChatGPT-5)
Other
Lead sponsor
MetroWest Artificial Intelligence Research Workgroup
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Music Therapy on Delirium

NCT03980782
View directory record Official record
Conditions
Delirium
Interventions
Music Therapy
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Scranton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Not applicable Interventional Results available

Short-term Atorvastatin's Effect on Acute Kidney Injury Following Cardiac Surgery

NCT00791648
View directory record Official record
Conditions
Acute Kidney Injury, Post-Operative Delirium, Icu Delirium, Acute Renal Failure, Delirium
Interventions
atorvastatin, placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Oct 24, 2026, 9:46 AM EDT
Active, not recruiting Not applicable Interventional

PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children

NCT03860168
View directory record Official record
Conditions
Critical Illness
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
0 Years to 24 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Neuromonitoring During Cardiac Procedures

NCT02681731
View directory record Official record
Conditions
Delirium, Stroke, Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 100 Years
Enrollment
250,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Oct 24, 2026, 9:46 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Delirium Recall in Advanced Cancer Patients

NCT00493714
View directory record Official record
Conditions
Advanced Cancer, Delirium
Interventions
Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Not applicable Interventional

Assessing the Effects of Robotic Pets on Patients With Dementia in the Acute Care Hospital Setting

NCT06683443
View directory record Official record
Conditions
Dementia, Delirium
Interventions
Robotic Joy for All™ pet
Behavioral
Lead sponsor
Sarasota Memorial Health Care System
Other
Eligibility
65 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 2 Interventional Results available

Study of Efficacy of PEAR-004 in Schizophrenia

NCT03751280
View directory record Official record
Conditions
Schizophrenia
Interventions
PEAR-004, Sham
Device
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Garden Grove, California • Oakland, California • Torrance, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 3 Interventional Results available

The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure

NCT01739933
View directory record Official record
Conditions
Sepsis, Delirium, Impaired Cognition
Interventions
Dexmedetomidine, Propofol
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
11
States / cities
San Francisco, California • Baton Rouge, Louisiana • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Oct 24, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation

NCT05915377
View directory record Official record
Conditions
Delirium, Delirium in Old Age, Delirium With Dementia, Delirium Superimposed on Dementia
Interventions
READI-SET GO UB-CAM delirium screening into EHR
Other
Lead sponsor
Penn State University
Other
Eligibility
70 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer

NCT01949662
View directory record Official record
Conditions
Advanced Cancers
Interventions
Lorazepam, Placebo, Haloperidol decanoate, Questionnaires
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Recruiting No phase listed Observational

Pervasive Sensing and AI in Intelligent ICU

NCT05127265
View directory record Official record
Conditions
Critical Illness, Pain, Delirium, Confusion
Interventions
Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring, Light Level Monitoring, Air Quality Monitoring, EKG Monitoring, Vitals Monitoring, Biosample Collection, Delirium Motor Subtyping Scale 4 (DMSS-4)
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Confusion in the Elderly After Colon Surgery

NCT01623297
View directory record Official record
Conditions
Confusion, Inflammation, Acute Phase Reaction, Surgery, Delirium
Interventions
Not listed
Lead sponsor
New York Hospital Queens
Other
Eligibility
65 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Jun 19, 2012 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 2 Interventional

Cognitive Intervention For Delirium in Dementia

NCT01267682
View directory record Official record
Conditions
Delirium, Dementia
Interventions
Cognitive Stimulation
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
9
States / cities
Bellefonte, Pennsylvania • Dallas, Pennsylvania • Harrisburg, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 3 Interventional

A Trial to Reduce Delirium in Aged Post Acute Patients

NCT00182936
View directory record Official record
Conditions
Delirium, Aging
Interventions
Delirium Abatement Program
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2006 · Synced Oct 24, 2026, 9:46 AM EDT
Recruiting Not applicable Interventional

Short-term And Longer-term Cognitive Impact Of Neurochecks

NCT06219889
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Frequency of neurochecks
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 24, 2026, 9:46 AM EDT
Active, not recruiting Not applicable Interventional

CTSN Embolic Protection Trial

NCT06027788
View directory record Official record
Conditions
Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease
Interventions
CardioGard Embolic Protection Cannula, Standard Aortic Cannula
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years and older
Enrollment
842 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
20
States / cities
North Little Rock, Arkansas • Los Angeles, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 2 Interventional Results available

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

NCT02554253
View directory record Official record
Conditions
Cognitive Disorders, Delirium, Acute Kidney Injury
Interventions
Ketamine, Propofol
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
75 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 24, 2026, 9:46 AM EDT
Completed Phase 2 Interventional Results available

Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium

NCT00351299
View directory record Official record
Conditions
Delirium, Agitation
Interventions
Dexmedetomidine, Standard of Care
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2017 · Synced Oct 24, 2026, 9:46 AM EDT
Not listed Not applicable Interventional

Acute Care for Elders (ACE) Program at OHSU Hospital

NCT02119078
View directory record Official record
Conditions
Delirium, Age-Related Cognitive Decline, Frail Elderly, Hospital Acquired Pressure Ulcer, Drug-Related Side Effects and Adverse Reactions
Interventions
Acute Care of Elders focused geriatric care
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 24, 2026, 9:46 AM EDT