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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:21 PM EDT

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Showing 49–72 of 138 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adenoma Colon Polyp Clear all
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Aspirin/Folate Prevention of Large Bowel Polyps

NCT00272324
View directory record Official record
Conditions
Colorectal Cancer, Polyps, Adenomas
Interventions
Aspirin, Folate
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
1,121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2007
U.S. locations
8
States / cities
Los Angeles, California • Denver, Colorado • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Standard Colonoscopy Versus Colonoscopy With Endocuff Vision

NCT03361917
View directory record Official record
Conditions
Colorectal Polyp, Colorectal Adenoma, Colon Cancer
Interventions
Endocuff Vision
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Oct 17, 2026, 11:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Curcumin for the Chemoprevention of Colorectal Cancer

NCT00118989
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
Curcuminoids
Dietary Supplement
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 17, 2026, 11:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Endoscopic Size Assessment of Advanced Adenomatous Polyps

NCT02193646
View directory record Official record
Conditions
Adenoma Detection Rate Improvement in Screening Colonoscopy
Interventions
Not listed
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 80 Years
Enrollment
1,930 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas

NCT05389397
View directory record Official record
Conditions
Polyp of Colon
Interventions
Outreach
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
54 Years to 70 Years
Enrollment
604 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 17, 2026, 11:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening and Risk Factors of Colon Neoplasia

NCT01647776
View directory record Official record
Conditions
Colon Cancer
Interventions
Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
30 Years to 80 Years
Enrollment
3,315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

AI Colorectal Polyp Detection

NCT04979962
View directory record Official record
Conditions
Polyp Colorectal, Adenoma Colon
Interventions
EW10-EC02 (Endoscopy Support Program)
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
45 Years and older
Enrollment
1,162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
10
States / cities
Los Angeles, California • Largo, Florida • Chestnut Hill, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 17, 2026, 11:21 PM EDT
Recruiting No phase listed Observational

St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)

NCT05402696
View directory record Official record
Conditions
Colon Adenoma, Colon Polyp, Colon Lesion
Interventions
Endoscopic tissue resection
Procedure
Lead sponsor
University of British Columbia
Other
Eligibility
18 Years and older
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Saint Cloud, Minnesota
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety Study of SIC 8000 in Subjects Undergoing Endoscopic Mucosal Resection (EMR) of Colonic Lesions Equal to or Larger Than 2 cm

NCT02654418
View directory record Official record
Conditions
Adenomas
Interventions
Endoscopic Mucosal Resection of large colon polyps (greater than or equal to 20 mm in size)
Procedure
Lead sponsor
Cosmo Technologies Ltd
Industry
Eligibility
18 Years and older
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
3
States / cities
Jacksonville, Florida • Indianapolis, Indiana • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 17, 2026, 11:21 PM EDT
Completed No phase listed Observational

A Double Balloon Endoscopic Platform for ESD

NCT03551379
View directory record Official record
Conditions
Colon Adenoma, Colon Polyp
Interventions
Double Balloon Endoluminal Platform
Device
Lead sponsor
Lumendi, LLC
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Trial of an Endoscopic Quality Improvement Project

NCT02325635
View directory record Official record
Conditions
Colon Polyps
Interventions
Educational Training
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Phase 3 Interventional

Polyp Prevention Trial

NCT00339625
View directory record Official record
Conditions
Diet, Polyps, Adenoma
Interventions
low fat, high fiber, high fruit and vegetable eating plan
Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
35 Years to 99 Years
Enrollment
2,079 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 15, 2020 · Synced Oct 17, 2026, 11:21 PM EDT
Withdrawn No phase listed Observational

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

NCT03027401
View directory record Official record
Conditions
Neoplasms, Adenomatous Polyposis Coli, Neurofibroma, Plexiform, Myelodysplastic Syndromes
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Up to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional

Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT01383252
View directory record Official record
Conditions
Colon Polyp
Interventions
Water infusion in lieu of air insufflation, Air method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Phase 2 Interventional

Calcium and Vitamin D vs Markers of Adenomatous Polyps

NCT00208793
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
Calcium and vitamin D3 combined, Placebo, Calcium, Vitamin D3
Dietary Supplement · Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 74 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Oct 17, 2026, 11:21 PM EDT
Recruiting No phase listed Observational

Familial Investigations of Childhood Cancer Predisposition

NCT03050268
View directory record Official record
Conditions
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML, BAP1 Tumor Predisposition Syndrome, Carney Complex, Choroid Plexus Carcinoma, Constitutional Mismatch Repair Deficiency Syndrome, Diamond-Blackfan Anemia, DICER1 Syndrome, Dyskeratosis Congenita, Emberger Syndrome, Familial Acute Myeloid Leukemia, Familial Adenomatous Polyposis, Fanconi Anemia, Familial Cancer, Familial Wilms Tumor, Familial Neuroblastoma, GIST, Hereditary Breast and Ovarian Cancer, Hereditary Paraganglioma-Pheochromocytoma Syndrome, Hodgkin Lymphoma, Juvenile Polyposis, Li-Fraumeni Syndrome, Lynch Syndrome, MDS, Melanoma Syndrome, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2, Neuroblastoma, Neurofibromatosis Type 1, Neurofibromatosis Type II, Nevoid Basal Cell Carcinoma Syndrome, Non Hodgkin Lymphoma, Noonan Syndrome and Other Rasopathy, Overgrowth Syndromes, Pancreatic Cancer, Peutz-Jeghers Syndrome, Pheochromocytoma/Paraganglioma, PTEN Hamartoma Tumor Syndrome, Retinoblastoma, Rhabdoid Tumor Predisposition Syndrome, Rhabdomyosarcoma, Rothmund-Thomson Syndrome, Tuberous Sclerosis, Von Hippel-Lindau Disease
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2037
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 17, 2026, 11:21 PM EDT
Terminated Phase 2 Interventional

Testing Obeticholic Acid for Familial Adenomatous Polyposis

NCT05223036
View directory record Official record
Conditions
Attenuated Familial Adenomatous Polyposis, Colorectal Carcinoma, Duodenal Carcinoma, Familial Adenomatous Polyposis
Interventions
Biopsy Procedure, Biospecimen Collection, Gastrointestinal Endoscopy, Obeticholic Acid, Placebo Administration, Questionnaire Administration
Procedure · Biological · Drug + 1 more
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Scottsdale, Arizona • Kansas City, Kansas • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 17, 2026, 11:21 PM EDT
Not listed Not applicable Interventional

Augmentation of Screening Colonoscopy With Fecal Immunochemical Testing

NCT00892593
View directory record Official record
Conditions
Colon Cancer
Interventions
Fecal Immunochemical Testing
Device
Lead sponsor
Forsyth Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
3
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy

NCT01917513
View directory record Official record
Conditions
Adenoma, Polyps, Colorectal Cancer
Interventions
G-EYE™ colonoscopy, Standard Colonoscopy
Device
Lead sponsor
Smart Medical Systems Ltd.
Industry
Eligibility
50 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Detection and Classification of Colon Polyps

NCT00825292
View directory record Official record
Conditions
Colon Polyps
Interventions
Polp removal and identification, colon polyp removal, ETMI colonoscope (ETMI scope is a FDA approved device)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 17, 2026, 11:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Complete Histologic Resection of Adenomatous Polyps?

NCT01224444
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
standard polypectomy snare
Other
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
40 Years to 85 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Lebanon, New Hampshire • White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Phase 2 Interventional Results available

Curcumin in Treating Patients With Familial Adenomatous Polyposis

NCT00641147
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Curcumin, Laboratory Biomarker Analysis, Placebo
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 29, 2017 · Synced Oct 17, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Water Immersion and Polyp Detection: A Randomized Controlled Trial

NCT03231917
View directory record Official record
Conditions
Adenoma, Colonic Neoplasms
Interventions
Water Infusion first, CO2 Insufflation First
Procedure
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
50 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Farmington, Connecticut • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 17, 2026, 11:21 PM EDT
Enrolling by invitation Not applicable Interventional

Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection

NCT06462521
View directory record Official record
Conditions
Colon Cancer, Colon Polyp, Colon Adenoma, Serrated Polyp
Interventions
Cold Snare Piecemeal Resection (CSPR), Cold Snare Endoscopic Mucosal Resection (Cold EMR)
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 17, 2026, 11:21 PM EDT