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Showing 1–24 of 134 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Alcohol Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Strategies: Motivational Interviewing/Psychoeducation

NCT03458299
View directory record Official record
Conditions
Alcohol Use, Underage, Substance Use, Underage Drinking
Interventions
Motivational Interviewing, Psychoeducation
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
13 Years to 20 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Valley Center, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Jul 21, 2026, 10:20 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Phase 1 Interventional

Brief Alcohol Intervention for Adolescents Who Have Attempted Suicide

NCT02426957
View directory record Official record
Conditions
Suicide, Alcohol Drinking
Interventions
motivational enhancement therapy
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Jul 21, 2026, 10:20 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Journey of Transformation Curriculum for Native American Youth

NCT05731713
View directory record Official record
Conditions
Alcohol Drinking, Tobacco Use, Substance Use, Sexual Behavior
Interventions
Journey of Transformation-Native Youth Health Leadership Program curriculum
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 16 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Phase 1Phase 2 Interventional

Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use

NCT00907309
View directory record Official record
Conditions
Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
Interventions
iMET, iMET/TE
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Jul 21, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Student Athlete Testing Using Random Notification

NCT00451854
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse, Substance Abuse
Interventions
Random, no advanced notice drug and alcohol testing
Procedure
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 19 Years
Enrollment
14,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Alcohol and Other Drug Use and Violence Among Latino Youth

NCT05240313
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
kiR venezolano
Behavioral
Lead sponsor
Boston College
Other
Eligibility
11 Years to 14 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Doral, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Jul 21, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nen ŨnkUmbi/EdaHiYedo Plus (We Are Here Now Plus): a Multi-level Intervention to Reduce Health Disparities Among American Indian Youth

NCT07460973
View directory record Official record
Conditions
Healthy, Condom Use, Mental Health, Substance Use (Drugs, Alcohol)
Interventions
NE+, Control
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
12 Years to 18 Years
Enrollment
843 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
View directory record Official record
Conditions
Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digitally Prompted Parenting: A Text Message Parent-Based Alcohol Intervention for Incoming College Students

NCT06861660
View directory record Official record
Conditions
Underage Drinking
Interventions
Digitally Prompted Parenting, Active Control
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cultural Adaptation of Drug Treatment for DJJ Youth

NCT06003725
View directory record Official record
Conditions
Substance Use
Interventions
Culturally Adapted Adolescent Substance Use Treatment
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 17 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
San Francisco, California • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Screening in an Ethnically Diverse Sample of Adolescents in Primary Care

NCT01797835
View directory record Official record
Conditions
Alcohol Use, Drug Use
Interventions
CHAT brief MI intervention, usual care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 18 Years
Enrollment
294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
North Hollywood, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Facilitating Adolescent Self-Change for Alcohol Problems

NCT01690026
View directory record Official record
Conditions
Underage Drinking
Interventions
Motivation interviewing based brief intervention, Standard Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
14 Years to 19 Years
Enrollment
1,209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
3
States / cities
Miami, Florida • Minneapolis, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 21, 2026, 10:20 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Citicoline in Youth Alcohol Use Disorder

NCT05870111
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Citicoline (cytidine diphosphate-choline), Placebo oral capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 22 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Not listed Phase 1Phase 2 Interventional

Reducing Driving Offenses of Adolescent Drinkers

NCT00851058
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Brief group counseling, Community Counseling, Prototypic community service
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
16 Years to 20 Years
Enrollment
786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 24, 2011 · Synced Jul 21, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional

Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care

NCT07059078
View directory record Official record
Conditions
Adolescent Alcohol Use
Interventions
Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 17 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
13
States / cities
Baltimore, Maryland • Belcamp, Maryland • Bowie, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 21, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
View directory record Official record
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 21, 2026, 10:20 PM EDT
Withdrawn Phase 1 Interventional

Trial of Computerized MET for Adolescent Substance Use

NCT01784653
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse, Nicotine Dependence
Interventions
iMET, MET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

2 College Truths and 1 Lie

NCT06576011
View directory record Official record
Conditions
Underage Drinking
Interventions
Gamified Social Norms Marketing Campaign, Social Norms Marketing Campaign
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
18 Years to 20 Years
Enrollment
392 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study

NCT01616212
View directory record Official record
Conditions
Substance Use Disorder, Delinquency
Interventions
Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents, Drug Education for adolescents
Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 9, 2014 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

NCT04160754
View directory record Official record
Conditions
Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions
Mindfulness Based Relapse Prevention, Control (CTL)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cannabidiol in Youth Alcohol Use Disorder

NCT05317546
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cannabidiol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 22 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jul 21, 2026, 10:20 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

PARTNER Recruitment and Brief Intervention Pilot Study

NCT00735956
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2010 · Synced Jul 21, 2026, 10:20 PM EDT