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ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:45 AM EDT

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Showing 1–24 of 466 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adolescent Depression Clear all
Recruiting Not applicable Interventional

Telehealth Behavioral Activation for Teens

NCT06273995
View directory record Official record
Conditions
Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild, Depression Moderate, Depression Severe
Interventions
Behavioral Activation
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 24, 2026, 5:45 AM EDT
Withdrawn Not applicable Interventional

Integrated Behavioral Health Innovations in Childhood Chronic Illness Care Delivery Systems

NCT02740309
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Integrated Brief Behavior Therapy (IBBT) Intervention, Treatment as usual
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2018 · Synced Oct 24, 2026, 5:45 AM EDT
Not listed Phase 4 Interventional

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

NCT04245436
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Duloxetine, Escitalopram
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

NCT04785677
View directory record Official record
Conditions
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety, Substance Use, Aggression, Coping Skills, Impulsive Behavior, Housing Problems, Recidivism, Stress, Occupational Stress, Psychological Distress
Interventions
Resiliency in Stressful Experiences (RISE) Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 24, 2026, 5:45 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Transforming Adolescent Mental Health Through Accessible, Scalable, Technology-supported Small-group Instruction

NCT05860257
View directory record Official record
Conditions
Anxiety Depression, Suicidal Ideation
Interventions
PeerLearning.net
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
14 Years to 65 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Tempe, Arizona • Eugene, Oregon • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Process and Outcomes in CBT for Anxious and Depressed Youth

NCT03100279
View directory record Official record
Conditions
Anxiety Disorders, Depression
Interventions
Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
7 Years to 17 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2020
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Phase 3 Interventional Results available

Open-label Ziprasidone Study for Psychosis Treatment in Adolescents

NCT00421954
View directory record Official record
Conditions
Schizophreniform Disorder, Schizoaffective Disorder, Psychosis, Depressive Disorder, Major, Bipolar Disorder
Interventions
Ziprasidone
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Ukrainian Student Problem Solving Project

NCT06064578
View directory record Official record
Conditions
Trauma, Anxiety, Depression, Child Behavior
Interventions
Project SOLVE
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
10 Years to 18 Years
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Oct 24, 2026, 5:45 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Girls in Transition Study: Helping Girls Enter the Teenage Years

NCT00641940
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Girls in Transition (GT) program, Waitlist Control
Behavioral
Lead sponsor
Swarthmore College
Other
Eligibility
Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Swarthmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2008 · Synced Oct 24, 2026, 5:45 AM EDT
Completed No phase listed Observational

A Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults

NCT01778478
View directory record Official record
Conditions
Depression, Anxiety Disorder, Cancer
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

NCT03940508
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Making Connections Intervention, IPT-A
Behavioral
Lead sponsor
New York University
Other
Eligibility
12 Years to 20 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 24, 2026, 5:45 AM EDT
Completed No phase listed Observational

A Retrospective Study to Evaluate NeuroStar® Advanced Therapy in Adolescents

NCT06699940
View directory record Official record
Conditions
MDD
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Neuronetics
Other
Eligibility
12 Years to 21 Years
Enrollment
7,690 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Malvern, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lakota Family Acceptance Project

NCT07326748
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Adapted Lakota Family Acceptance Program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Pine Ridge, South Dakota • Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 24, 2026, 5:45 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating an Online Wellness Intervention for Greek Adolescents

NCT04815681
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Happiness
Interventions
Common Elements Toolbox, Active Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 20 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Bending Adolescent Depression Trajectories Through Personalized Prevention

NCT01948167
View directory record Official record
Conditions
Depression
Interventions
Interpersonal Psychotherapy- Adolescent Skills Training, Coping with Stress
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
4
States / cities
Denver, Colorado • Champaign, Illinois • Piscataway, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available

Concurrent Treatment for Depressed Parents and DepressedAdolescents

NCT00951821
View directory record Official record
Conditions
Depression, Suicide
Interventions
Concurrent treatment, Adolescent treatment only
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 31, 2015 · Synced Oct 24, 2026, 5:45 AM EDT
Recruiting No phase listed Observational

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

NCT05329441
View directory record Official record
Conditions
Depression in Adolescence
Interventions
Trier Social Stress Test (TSST)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 21 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Bupropion for Treating Nicotine Dependence in Young People

NCT00129272
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
Bupropion-SR, Placebo
Drug · Other
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
12 Years to 25 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional

T- BOOM Teens--Building Options and Opportunities for Moms

NCT00745537
View directory record Official record
Conditions
Postpartum Major Depression
Interventions
repeated mood measures and phone depression care management
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 17 Years · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Technology Assisted Programs That Promote Mental Health for Teenagers

NCT01912729
View directory record Official record
Conditions
Depression
Interventions
Networked Peer Support with Peer Guide, Networked Peer Support with Clinician Coach
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
14 Years to 19 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mood and Insulin Resistance in Adolescents At-Risk for Diabetes

NCT01425905
View directory record Official record
Conditions
Depression, Impaired Glucose Tolerance
Interventions
The Blues Program, Hey Durham
Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
12 Years to 17 Years · Female only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Mentalization-Based Therapy to Prevent Suicidal Behavior in Adolescents With Bipolar Disorder

NCT02129790
View directory record Official record
Conditions
Bipolar Disorder, Suicidal Ideation
Interventions
Mentalization-Based Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Life Experiences in Adolescents and the Development of Skills

NCT04719897
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
FIRST: Repairing Thoughts
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 24, 2026, 5:45 AM EDT
Completed Phase 3 Interventional

Omega-3 Fatty Acids for Treatment of Depression in Adolescents

NCT00658476
View directory record Official record
Conditions
Depression
Interventions
Fish Oil, Cognitive Behavior Therapy, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2012 · Synced Oct 24, 2026, 5:45 AM EDT