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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Depression Clear all
Completed Not applicable Interventional

The Reducing Risk Study

NCT03665337
View directory record Official record
Conditions
Insomnia, Delayed Sleep Phase
Interventions
mTranS-C, Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
12 Years to 18 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 20, 2026, 10:55 AM EDT
Withdrawn Not applicable Interventional

Social Media Use in Adolescents Admitted to a Psychiatric Unit

NCT03836846
View directory record Official record
Conditions
Depression, Social Media, Adolescent Behavior
Interventions
CBT Mobile App, Treatment as usual
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
13 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chino, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional

A PK/PD Genetic Variation Treatment Algorithm Versus Treatment As Usual for Adolescent Management Of Depression

NCT02286440
View directory record Official record
Conditions
Depression
Interventions
AssureRx GeneSight genotyping results, Treatment as usual
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 18 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Screening Wizard, Component 1 of iCHART (Integrated Care to Help At-Risk Teens)-Feasibility/Pilot Phase

NCT03985813
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Screening Wizard
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 26 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Cranberry Township, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2022 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth

NCT05697627
View directory record Official record
Conditions
Depression, Subclinical Depressive Symptoms
Interventions
Computerized cognitive training (CCT) using EndeavorRx
Device
Lead sponsor
University of Michigan
Other
Eligibility
9 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 20, 2026, 10:55 AM EDT
Completed No phase listed Observational

Improving Adolescent Health Outcomes Through Preventive Care Transformation

NCT02244138
View directory record Official record
Conditions
Sexually Transmitted Diseases, Depression Diagnosis, Substance Use Disorders
Interventions
Adolescent CDSS
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 21 Years
Enrollment
2,831 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Unified Protocol for Adolescents (UP-A) Change Processes

NCT03102008
View directory record Official record
Conditions
Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem, Emotional Disorder
Interventions
Unified Protocol for Emotional Disorders in Adolescents (UP-A)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Depression Prevention Program for Adolescents

NCT00183417
View directory record Official record
Conditions
Depression
Interventions
Cognitive behavior therapy (CBT), Supportive/expressive (S/E) therapy, Bibliotherapy
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
14 Years to 18 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2012 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Transphobia Among Adolescents Through a Brief Video Intervention

NCT04969003
View directory record Official record
Conditions
Transgenderism, Depression
Interventions
Short videos
Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Determining Optimal Continuation Treatment Duration for Depressed Children and Adolescents

NCT00332787
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
7 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Sep 20, 2026, 10:55 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Educational Intervention for Optimizing Adolescent Mental Health Screening and Treatment in Pediatric Residency

NCT00768352
View directory record Official record
Conditions
Mental Health
Interventions
Educational intervention
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2008 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of an Entrepreneurship Program for American-Indian Youth

NCT02157493
View directory record Official record
Conditions
Depressive Symptoms, Substance Use
Interventions
Arrowhead Business Group Curriculum, Recreational League Control Condition
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years to 15 Years
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Phase 3 Interventional

A Double-Blind Randomized Placebo Controlled Study of Quetiapine for the Treatment of Depression in Adolescents With Bipolar Disorder

NCT00232414
View directory record Official record
Conditions
Bipolar I Disorder
Interventions
Quetiapine
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Sep 20, 2026, 10:55 AM EDT
Terminated Not applicable Interventional Results available

iTBS in Refractory Pediatric Depression

NCT03845504
View directory record Official record
Conditions
Depression
Interventions
Intermittent Theta Burst Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology

NCT03132298
View directory record Official record
Conditions
Anxiety Symptoms, Depressive Symptoms
Interventions
Implicit Theories of Personality Program, Control Program
Other
Lead sponsor
Harvard University
Other
Eligibility
12 Years to 15 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Boricua Youth Study COVID-19 Coping Intervention Study

NCT05444881
View directory record Official record
Conditions
Psychological Stress, Depression, Anxiety
Interventions
Mindfulness-based Intervention (Headspace TM)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 20, 2026, 10:55 AM EDT
Not listed Phase 4 Interventional

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

NCT04245436
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Duloxetine, Escitalopram
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Phase 1 Interventional

Teen Depression Awareness Project (TDAP)

NCT00099827
View directory record Official record
Conditions
Depression
Interventions
Education
Behavioral
Lead sponsor
RAND
Other
Eligibility
13 Years to 17 Years
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
8
States / cities
Los Angeles, California • San Fernando, California • Washington D.C., District of Columbia + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2011 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors

NCT03868761
View directory record Official record
Conditions
Disaster, PTSD, Adolescent Behavior, Trauma, Anxiety, Stress
Interventions
Sonoma Rises
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder

NCT00511810
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Low Dose Fish Oil, High Dose Fish Oil
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth

NCT03034720
View directory record Official record
Conditions
Concussion, Brain, TBI, Depression, Anxiety
Interventions
Collaborative Care
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 20, 2026, 10:55 AM EDT
Recruiting Not applicable Interventional

Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence

NCT07812870
View directory record Official record
Conditions
Autism, Depressed, Depressed Mood
Interventions
BA-A
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
12 Years to 17 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 20, 2026, 10:55 AM EDT
Completed No phase listed Observational

Ability to Cope With Type 1 Diabetes

NCT00206349
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 21 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Sep 20, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Concurrent Treatment for Depressed Parents and DepressedAdolescents

NCT00951821
View directory record Official record
Conditions
Depression, Suicide
Interventions
Concurrent treatment, Adolescent treatment only
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 30, 2015 · Synced Sep 20, 2026, 10:55 AM EDT