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Showing 1–24 of 453 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Overweight Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Beverage Choice and Lifestyle Modification in Overweight Youth

NCT01662570
View directory record Official record
Conditions
Obesity
Interventions
Beverage Choice and Lifestyle Modification, Nutrition Education (NE)
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
4 Years to 8 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2012 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Depression & Insulin Sensitivity in Adolescents

NCT03263351
View directory record Official record
Conditions
Type2 Diabetes, Type 2 Diabetes Mellitus, Insulin Sensitivity, Insulin Resistance, Depression, Adolescent Obesity
Interventions
Cognitive-behavioral therapy group, Health education group
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional

REACH-OUT: Chicago Children's Diabetes Prevention Program

NCT00723853
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Reach-Out Program, nutritional and exercise program, Reach-In Program, standard of care
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
9 Years to 65 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Jul 22, 2026, 10:26 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years

NCT03338296
View directory record Official record
Conditions
Obesity
Interventions
lorcaserin hydrochloride XR, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
12 Years to 17 Years
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
16
States / cities
Phoenix, Arizona • Bell Gardens, California • Long Beach, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2021 · Synced Jul 22, 2026, 10:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Amylin and Incretins on Postprandial Metabolisms in Adolescents With Type 2 Diabetes Mellitus (T2DM).

NCT00361946
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2017 · Synced Jul 22, 2026, 10:26 AM EDT
Active, not recruiting Not applicable Interventional

Low GI Diet in Children and Adolescents With ALL

NCT03157323
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Pediatric, Obesity, Pediatric
Interventions
Low Glycemic Index Diet
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 21 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
5
States / cities
Hartford, Connecticut • Washington D.C., District of Columbia • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 22, 2026, 10:26 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Impact of Exergaming on Adolescent Youth

NCT01374386
View directory record Official record
Conditions
Childhood Obesity
Interventions
Exergaming
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
12 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Challenge!, a Health Promotion/ Obesity Prevention Program for Teens

NCT00746083
View directory record Official record
Conditions
Overweight
Interventions
Challenge!
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
11 Years to 16 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 15, 2019 · Synced Jul 22, 2026, 10:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Healthy Body Study

NCT02011646
View directory record Official record
Conditions
Obesity
Interventions
Healthy Weight, Controlled Intervention
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 24 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Jul 22, 2026, 10:26 AM EDT
Terminated Not applicable Interventional Results available

Unsweetened Sparkling Water and Changes in Sweetness Perception in Adolescents

NCT05966870
View directory record Official record
Conditions
Obesity, Adolescent, PreDiabetes
Interventions
Unsweetened flavored sparkling water
Other
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 21 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Prevention Program for Obese Latino Youth

NCT02039141
View directory record Official record
Conditions
Obesity, Insulin Resistance, Diabetes
Interventions
Every Little Step Counts Intervention
Other
Lead sponsor
Arizona State University
Other
Eligibility
14 Years to 16 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 22, 2026, 10:26 AM EDT
Terminated Phase 1 Interventional

Study of Fish Oil to Reduce ALT Levels in Adolescents

NCT00694746
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease, Fatty Liver
Interventions
Omega-3-acid ethyl esters, Placebo
Drug
Lead sponsor
Boston University
Other
Eligibility
13 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Reducing Obesity and Type 2 Diabetes in High Risk Youth

NCT01560676
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
HEALTH[e]TEEN, HEALTH[e]TEEN + CST
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 18 Years
Enrollment
384 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 21, 2012 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Phase 2 Interventional

Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity

NCT00680979
View directory record Official record
Conditions
Obesity, Overweight, Binge Eating
Interventions
Interpersonal Psychotherapy, Health Education
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
12 Years to 17 Years · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project EAT: Eating and Attitudes in Teens

NCT03085160
View directory record Official record
Conditions
Obesity, Adolescent Development, Stress
Interventions
Learning to Breathe, Health Education
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Jul 22, 2026, 10:26 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study

NCT03584217
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity, Nephropathy, Adolescent Obesity
Interventions
Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Renal Biopsy
Drug · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jul 22, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

Pain and Weight Treatment: Development and Trial of PAW

NCT04046562
View directory record Official record
Conditions
Obesity, Adolescent, Pain, Chronic, CBT
Interventions
PAW, Pain Education
Behavioral
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Brain, Appetite, Teens, and Exercise

NCT03783390
View directory record Official record
Conditions
Energy Balance, Appetitive Behavior, Obesity
Interventions
Exercise Intervention, Newsletter
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
14 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Jul 22, 2026, 10:26 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

NCT05008276
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Adolescent Obesity, Pre Diabetes, Kidney Hypoxia, Puberty
Interventions
Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Dextran 40
Drug
Lead sponsor
Petter Bjornstad
Other
Eligibility
8 Years to 14 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Jul 22, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy Trial of Healthy Together ("Juntos")

NCT06489262
View directory record Official record
Conditions
Obesity, Activity, Motor, Diet, Healthy
Interventions
Healthy Together ("Juntos")
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 15 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 22, 2026, 10:26 AM EDT
Completed Phase 1 Interventional

A School Nurse-Delivered Intervention for Overweight and At Risk Adolescents

NCT00682188
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Counseling Intervention, Information Intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
13 Years to 18 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2014 · Synced Jul 22, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

Sanctuary Farm Prescription in Adolescents

NCT07218588
View directory record Official record
Conditions
Obesity &Amp; Overweight, Adolescence
Interventions
dietary / produce
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 22, 2026, 10:26 AM EDT
Completed No phase listed Observational

Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2016

NCT01031160
View directory record Official record
Conditions
Adolescent Health
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
15 Years to 22 Years
Enrollment
4,902 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 22, 2026, 10:26 AM EDT
Active, not recruiting Not applicable Interventional

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT05268042
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Moderately carbohydrate-restricted diet, Fat-restricted diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 22, 2026, 10:26 AM EDT