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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:59 AM EST

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Showing 1–24 of 168 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Adolescent Substance Abuse Clear all

Conditions: Substance Abuse
Interventions: drug prevention curriculum; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 14 Years to 19 Years
Enrollment: 225 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Marijuana Abuse
Interventions: MET, MOMENT; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 15 Years to 24 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 2
States / cities: Boston, Massachusetts • Jamaica Plain, Massachusetts

Conditions: Adolescent Substance Use
Interventions: Guiding Good Choices; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 11 Years to 12 Years
Enrollment: 3,636 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 3
States / cities: Oakland, California • Aurora, Colorado • Detroit, Michigan

Conditions: Substance-related Disorders, Depression, High-risk Sex
Interventions: iSBIRT, iSBIRT/TE; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
Interventions: c-ASBI; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 9 Years to 20 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 6
States / cities: Boston, Massachusetts • Cambridge, Massachusetts • Lexington, Massachusetts

Conditions: Substance Use Disorders
Interventions: Standard Contingency Management (CM), Enhanced Contingency Management (CM+); Behavioral
Lead sponsor: Oregon Social Learning Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Substance Use, Delinquency
Interventions: Miami Juvenile Drug Court-MDFT, Miami Juvenile Drug Court -TAU; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 18 Years
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 4
States / cities: Miami, Florida

Conditions: Cannabis Use Disorder, Mild, Cannabis Use Disorder, Moderate
Interventions: Cannabis Actions and Practices Resource for Parents; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Pre-natal Cocaine Exposure, Risk-Taking
Interventions: fMRI; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 20 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Child Abuse, Child Neglect, Risk Behavior, Delinquency, Mental Health Impairment, Substance Use, Educational Problems, Adolescent Development, Adolescent Behavior, Sexual Behavior, Child Maltreatment
Interventions: FHF-T; Behavioral
Lead sponsor: University of Denver; Other
Eligibility: 13 Years to 16 Years
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2044
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Adolescent Substance Abuse, Attention Deficit Hyperactivity Disorder
Interventions: Medication integration protocol; Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Cannabis Dependence
Interventions: N-Acetylcysteine; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 20 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Adolescent, Depression, Substance Use Disorders
Interventions: Adolescent Coping With Depression/Functional Family Therapy; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 17 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
Interventions: iMET, iMET/TE; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Marijuana Abuse, Sexual Risk Behaviors
Interventions: Behavior Therapy, Treatment as Usual; Behavioral · Other
Lead sponsor: Butler Hospital; Other
Eligibility: 15 Years to 24 Years · Female only
Enrollment: 326 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Substance Abuse
Interventions: Free2b, Attention-Placebo; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 15 Years to 17 Years
Enrollment: 1,216 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Marijuana Abuse
Interventions: MET/CBT, CM, BPT; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 153 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Alcohol Abuse
Interventions: cASBI+cMET, cASBI; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Use
Interventions: Prevention; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 11 Years to 13 Years · Female only
Enrollment: 916 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use, Sexual Risk Behaviors
Interventions: Risk Reduction Therapy for Adolescents, Usual services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Adolescent Substance Use
Interventions: Not listed
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Obesity, Adolescent, Healthy Nutrition, Sedentary Behavior, Drug Abuse
Interventions: Wakaya: Rising Up for Choctaw Youth Curriculum; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 12 Years to 19 Years
Enrollment: 176 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Durant, Oklahoma • Seattle, Washington

Conditions: Cannabis Use
Interventions: Stanford Smart Talk Cannabis Awareness and Prevention curriculum; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 10 Years to 20 Years
Enrollment: 658 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Attention Deficit and Disruptive Behavior Disorders, Marijuana Abuse
Interventions: Divalproex Sodium, Placebo; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 12 Years to 55 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: New York, New York

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Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

A Real-time, Contextual Intervention Using Mobile Technology to Reduce Marijuana Use in Youth

Guiding Good Choices for Health

Primary Care iSBIRT to Reduce Serious Teen Health Risks

Trial of Computerized SBI to Reduce Teen Alcohol Use

Enhancing Adolescent Substance Abuse Treatment

Family-Based Juvenile Drug Court Services

Pilot Test of Parent-Focused Cannabis-Related Actions and Practices Intervention for Adolescent Marijuana Abuse

Development of Reward Processing in Prenatally Exposed Adolescents and Young Adults

Fostering Healthy Futures for Teens: An RCT

Family-Based Protocol for Medication Integration in Treatment of Comorbid ASU/ADHD in Routine Care

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents

Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD

Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use

A Brief Marijuana Intervention for Adolescent Women - 1

Preventing Drug Abuse Among Sexual Minority Youth

Treatment for Adolescent Marijuana Abuse

Pilot Test of Computerized MET to Reduce Adolescent Alcohol Use

Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention

Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth

The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse

Wakaya: Rising Up for Choctaw Youth Health

Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults