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ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:13 AM EDT

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Showing 73–96 of 168 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adolescent Substance Abuse Clear all
Completed Not applicable Interventional

Integrated Treatment of Marijuana Abuse for HIV+ Youth

NCT00683488
View directory record Official record
Conditions
HIV Infections
Interventions
Focus Group, First Intervention Trial, Intervention Trial 2
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Los Angeles, California • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Phase 2 Interventional

Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial

NCT01823250
View directory record Official record
Conditions
Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions
Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
14 Years to 17 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment for Adolescent Marijuana Abuse

NCT00580671
View directory record Official record
Conditions
Marijuana Abuse
Interventions
MET/CBT, CM, BPT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 20, 2015 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

NCT05521321
View directory record Official record
Conditions
Cannabis Use
Interventions
Stanford Smart Talk Cannabis Awareness and Prevention curriculum
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
10 Years to 20 Years
Enrollment
658 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 2, 2026, 11:13 AM EDT
Not listed Not applicable Interventional

Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders

NCT00957775
View directory record Official record
Conditions
Substance-Related Disorders, Alcohol-Related Disorders, Marijuana Abuse
Interventions
Usual care, Computer-delivered ACRA
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
12 Years to 18 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced Oct 2, 2026, 11:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)

NCT07661823
View directory record Official record
Conditions
Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
Interventions
AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
Behavioral
Lead sponsor
Veterans Recovery Network Inc.
Other
Eligibility
17 Years to 99 Years
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2045
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 2, 2026, 11:13 AM EDT
Withdrawn No phase listed Observational

Brain-imaging and Adolescent Neuroscience Consortium

NCT01511679
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Transitional Treatment of Adolescents in Family Therapy

NCT00680381
View directory record Official record
Conditions
Substance Abuse
Interventions
MTI, Minimal Transitional Intervention, GTI, Group Transitional Intervention, STI, Systems Transitions Intervention
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional

Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance Abuse

NCT01959217
View directory record Official record
Conditions
Adherence, Substance Abuse
Interventions
PM Component Text Reminders
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
16 Years to 29 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
La Jolla, California • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SARA - Substance Abuse Research Assistant

NCT03255317
View directory record Official record
Conditions
Substance Use
Interventions
Reinforcers, Notifications
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 24 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention

NCT03368456
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
Interventions
S4E, Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Phase 2 Interventional

Aftercare for Adolescents Treated for Alcohol Abuse and Dependence

NCT00561041
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Brief phone aftercare intervention, individual aftercare therapy
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 20, 2007 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervening to Prevent Youth Access to Marijuana Phase II

NCT03073291
View directory record Official record
Conditions
Cannabis
Interventions
Responsible Marijuana Vendor Training
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
21 Years and older
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Oakland, California • Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 2, 2026, 11:13 AM EDT
Withdrawn Not applicable Interventional

Reducing Problematic Substance Use in Youth With Chronic Medical Conditions

NCT01709201
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional

An Integrated Treatment for Comorbid PTSD and Substance Abuse in Adolescents

NCT01825694
View directory record Official record
Conditions
Substance Abuse, Traumatic Stress
Interventions
Trauma-focused Substance Abuse Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 19 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2023 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Based Juvenile Drug Court Services

NCT01668303
View directory record Official record
Conditions
Substance Use, Delinquency
Interventions
Miami Juvenile Drug Court-MDFT, Miami Juvenile Drug Court -TAU
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
4
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2012 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional

An Evaluation of JUST Court in Yuma County, AZ

NCT02449057
View directory record Official record
Conditions
Substance Abuse, Adolescent Behavior, Juvenile Delinquency Unspecified
Interventions
JUST
Other
Lead sponsor
Pepperdine University
Other
Eligibility
13 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Yuma, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Oct 2, 2026, 11:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

NCT05014074
View directory record Official record
Conditions
HIV/AIDS
Interventions
Theater/Pilot Testing
Other
Lead sponsor
Yale University
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 2, 2026, 11:13 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Brief Integrative Alcohol Interventions for Adolescents

NCT01427465
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Brief Prevention Program Using Positive Image
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2011 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Substance Use Among Youth

NCT04752189
View directory record Official record
Conditions
Substance Abuse
Interventions
Enhanced Replicating Effective Programs (Enhanced REP), Standard implementation
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
14 Years to 99 Years
Enrollment
825 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 2, 2026, 11:13 AM EDT
Withdrawn Phase 4 Interventional

Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents

NCT01015066
View directory record Official record
Conditions
Opiate Addiction
Interventions
Buprenorphine/naloxone, Naltrexone
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
16 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2014 · Synced Oct 2, 2026, 11:13 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings

NCT01523444
View directory record Official record
Conditions
Substance Abuse
Interventions
computer-assisted Screening & Brief Advice, computer-assisted Screening & Brief Advice Plus
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Contingency Management for Adolescent Alcohol Abuse

NCT00595478
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Motivational Enhancement Therapy (MET)/CBT+CM, Motivational Enhancement Therapy (MET)/CBT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 2, 2026, 11:13 AM EDT
Completed Not applicable Interventional Results available

Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial

NCT00619255
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Alcohol Abuse, Alcohol Dependence
Interventions
Adolescent Trauma Support Program
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Oct 2, 2026, 11:13 AM EDT