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ClinicalTrials.gov public records Last synced Oct 4, 2026, 1:21 AM EDT

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Showing 121–144 of 168 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adolescent Substance Abuse Clear all
Completed Not applicable Interventional Results available

Screening and Brief Advice to Reduce Teen Substance Use

NCT00227877
View directory record Official record
Conditions
Substance Related Disorders
Interventions
cSBA - New England, USA, cSBA - Prague, CZR
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
2,695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
5
States / cities
Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Technology Enhanced Adolescent Mental Health (TEAM)

NCT05343039
View directory record Official record
Conditions
Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
Interventions
Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
Device
Lead sponsor
University of Notre Dame
Other
Eligibility
13 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
South Bend, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Test of Parent-Focused Cannabis-Related Actions and Practices Intervention for Adolescent Marijuana Abuse

NCT04923230
View directory record Official record
Conditions
Cannabis Use Disorder, Mild, Cannabis Use Disorder, Moderate
Interventions
Cannabis Actions and Practices Resource for Parents
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 3 Interventional

A Brief Marijuana Intervention for Adolescent Women - 1

NCT00227864
View directory record Official record
Conditions
Marijuana Abuse, Sexual Risk Behaviors
Interventions
Behavior Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
Butler Hospital
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 2 Interventional

Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment

NCT02125539
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Navigating my Journey program, Attention Control
Behavioral
Lead sponsor
Inflexxion, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2015 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 2Phase 3 Interventional Results available

N-Acetylcysteine for Youth Cannabis Use Disorder

NCT03055377
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
N-acetyl cysteine, Placebo oral capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
14 Years to 21 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder

NCT00399763
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Substance Abuse
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
12 Years to 19 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Differential Sensitivity Markers in Youth Drug Abuse Prevention

NCT02622451
View directory record Official record
Conditions
Adolescent Substance Use
Interventions
Teen Intervene, Everyday Parenting
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Martial Arts as Early Intervention for Teen Drug Abuse

NCT00956527
View directory record Official record
Conditions
Adolescent, Substance Use
Interventions
Modified traditional martial arts training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Adolescent Substance Abuse: Progressive Treatment

NCT00680576
View directory record Official record
Conditions
Substance Abuse
Interventions
CBT, Cognitive Behavioral Therapy, FFT, Family Functional Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 18 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 10, 2014 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation Processes in School-Based Substance Abuse Programs

NCT01755533
View directory record Official record
Conditions
Substance Use
Interventions
Rural curriculum, Classic curriculum
Other
Lead sponsor
Penn State University
Other
Eligibility
11 Years to 15 Years
Enrollment
2,827 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linking Families Together Study- A Randomized Trial to Raise Parental Monitoring

NCT02129153
View directory record Official record
Conditions
Adolescent Behaviors, Substance Abuse
Interventions
LIFT (Parent Information)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
11 Years to 15 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Preventing HIV/Aids in Drug Abusing Youth

NCT00680719
View directory record Official record
Conditions
HIV Infections
Interventions
IBFT /HIV prevention, IBFT
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
15 Years to 20 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2013
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

NCT00612482
View directory record Official record
Conditions
Substance Abuse
Interventions
drug prevention curriculum
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 19 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2011 · Synced Oct 4, 2026, 1:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cannabis Effects on Brain Morphology in Aging

NCT01874886
View directory record Official record
Conditions
Study Focuses on Brain Morphology and Cognition in Older Subjects
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 4, 2026, 1:21 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

NCT06077292
View directory record Official record
Conditions
Cannabis Use, THC, Marijuana Use, Cognitive Impairment, THC Vaping
Interventions
15% THC Potency Reduction, 35% THC Potency Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 25 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 4, 2026, 1:21 AM EDT
Withdrawn Phase 3 Interventional

Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT)

NCT01228890
View directory record Official record
Conditions
Depression, Anxiety, Externalizing Symptoms, Substance Abuse
Interventions
CATCH-IT, AMPE
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
13 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2012 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-based Prescription Opioid Abuse Prevention for Adolescents

NCT02737696
View directory record Official record
Conditions
Opioid Related Disorders
Interventions
Web-based prescription opioid prevention for adolescents, JustThinkTwice.gov website (DEA)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
435 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 19, 2020 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Spirit Study

NCT00356551
View directory record Official record
Conditions
Substance Abuse
Interventions
Family Spirit curriculum
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 24 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
5
States / cities
Fort Defiance, Arizona • Tuba City, Arizona • Whiteriver, Arizona + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders

NCT01257022
View directory record Official record
Conditions
Substance Use, Unsafe Sexual Behavior
Interventions
Familias Unidas
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 17 Years
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2014 · Synced Oct 4, 2026, 1:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Community-University Approach to Preventing HIV

NCT03938077
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage, Alcohol Use, Mental Health, Tobacco Use, HIV Testing
Interventions
Storytelling 4 Empowerment
Device
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 4, 2026, 1:21 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Community Youth Development Study: A Test of Communities That Care

NCT01088542
View directory record Official record
Conditions
Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior, Violence, Depression, Anxiety, Suicide, Sexually Transmitted Infection, Educational Attainment
Interventions
Communities That Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
10 Years and older
Enrollment
52,323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth

NCT01442753
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking, Alcohol Drinking, Drug Abuse
Interventions
Family-Skills Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 4, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cradling Our Future Through Family Strengthening Study

NCT00373750
View directory record Official record
Conditions
Substance Abuse, Post-partum Depression, Depression
Interventions
Family Spirit Intervention
Procedure
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
12 Years to 19 Years · Female only
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
5
States / cities
Fort Defiance, Arizona • San Carlos, Arizona • Tuba City, Arizona + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 4, 2026, 1:21 AM EDT