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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:11 AM EDT

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Showing 73–96 of 122 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adolescents With Type 2 Diabetes Clear all
Completed Phase 3 Interventional Results available

Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes

NCT00658021
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Placebo, Exenatide
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
10 Years to 17 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
31
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 27 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 3 Interventional Results available

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

NCT03429543
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Metformin, Insulin, Placebo, Linagliptin, Empagliflozin
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
10 Years to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
44
States / cities
Phoenix, Arizona • Tucson, Arizona • Orange, California + 39 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2024 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Type 2 Diabetes and the Brain in Adolescents

NCT03461510
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity, Pediatric Obesity, Insulin Resistance, Dysglycemia, Hyperglycemia
Interventions
Hyperglycemic clamp, Hyperinsulinemic Euglycemic clamp
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 1 Interventional

A Study to Test How New Long-acting Insulin (Insulin Icodec) Works in the Body of Children and Teenagers

NCT05790681
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Insulin icodec
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
10 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
21
States / cities
Los Angeles, California • New Haven, Connecticut • Jacksonville, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional

Finding the Patient's Voice Diabetes Prevention Programs

NCT02700503
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Prediabetic State
Interventions
Encourage 2.0
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 18 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Oct 9, 2026, 5:11 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study

NCT03584217
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity, Nephropathy, Adolescent Obesity
Interventions
Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Renal Biopsy
Drug · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 9, 2026, 5:11 AM EDT
Not yet recruiting Not applicable Interventional

Artificial Intelligence-based Methods to Predict Disease Progression in Youth With Type 2 Diabetes

NCT07116902
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
phone application, Standard of Care (SOC)
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 9, 2026, 5:11 AM EDT
Recruiting Not applicable Interventional

Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

NCT07270016
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Hyperglycemia, Physical Inactivity, Lifestyle (Sedentary Behavior and Physical Activity), Continuous Glucose Monitoring
Interventions
Healthmine app
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 24 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Amylin and Incretins on Postprandial Metabolisms in Adolescents With Type 2 Diabetes Mellitus (T2DM).

NCT00361946
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 2 Interventional

Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

NCT01007266
View directory record Official record
Conditions
Obesity, Diabetes Mellitus, Type 2, Abnormal Glucose Metabolism, Type 2 Diabetes
Interventions
Assignment of a Lay Patient Partner
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
12 Years to 20 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional Results available

Use of Continuous Glucose Monitors in Publicly-Insured Youth With Type 2 Diabetes - A Pilot and Feasibility Study

NCT05074667
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Continuous Glucose Monitor, Patient Reported Outcome Questionnaires
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 19 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional

United for Health: Type 2 Diabetes Prevention in Latino Teens

NCT03527641
View directory record Official record
Conditions
Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress, Adolescent Development, Family Research
Interventions
CookingMatters, Parent Education, Physical Activity, Health Education, Mindfulness-based Stress Reduction, Brief Mindfulness Intervention
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 15 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2019 · Synced Oct 9, 2026, 5:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of HIIT vs. TRE on Type 2 Diabetes Risk

NCT07215533
View directory record Official record
Conditions
Obesity and Type 2 Diabetes, Metabolic Diseases, High-intensity Interval Training, Time-restricted Eating
Interventions
High-intensity interval training, Time-restricted eating
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
14 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation

NCT05404711
View directory record Official record
Conditions
Overweight and Obesity, PreDiabetes, Insulin Resistance
Interventions
CGM
Device
Lead sponsor
Mary Ellen Vajravelu, MD
Other
Eligibility
8 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 9, 2026, 5:11 AM EDT
Recruiting No phase listed Observational

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

NCT06525259
View directory record Official record
Conditions
Diabetes Mellitus Type 2, Childhood-Onset
Interventions
Not listed
Lead sponsor
George Washington University
Other
Eligibility
8 Years to 15 Years
Enrollment
3,600 participants
Timeline
2024 – 2028
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 1 Interventional

Prevention of Type 2 Diabetes Mellitus in Children

NCT00073268
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Exercise
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
12 Years to 15 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 15, 2010 · Synced Oct 9, 2026, 5:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth

NCT00536250
View directory record Official record
Conditions
Impaired Glucose Tolerance, Pre-diabetes, Childhood Obesity, Insulin Resistance, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
8 Years to 22 Years
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 1 Interventional Results available

Pharmacokinetics, Pharmacodynamics, and Safety of Alogliptin in Children, Adolescents and Adults With Type 2 Diabetes Mellitus

NCT00957268
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Alogliptin
Drug
Lead sponsor
Takeda
Industry
Eligibility
10 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
7
States / cities
Miami, Florida • Pineallas Park, Florida • Louisville, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2015 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Insulin Resistance and Energy Metabolism Through Sleep Extension in Adolescents

NCT03814512
View directory record Official record
Conditions
Sleep, Diabetes Mellitus, Type 2
Interventions
Extended Sleep Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 19 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

NCT05260021
View directory record Official record
Conditions
Type2 Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, T2D, T2DM (Type 2 Diabetes Mellitus), Glucose Metabolism Disorders, Endocrine System Diseases, Metabolic Disease
Interventions
Tirzepatide Dose 1, Tirzepatide Dose 2, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
10 Years to 18 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
13
States / cities
Los Angeles, California • Sacramento, California • San Diego, California + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Not applicable Interventional

Telehealth Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes

NCT05396443
View directory record Official record
Conditions
Obesity, Childhood, Type2Diabetes
Interventions
Black Girls for Wellness Telehealth
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Completed No phase listed Observational

Designing Team Clinic for Youth With Type 2 Diabetes

NCT06658743
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Los Angeles, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Recruiting Not applicable Interventional

Type 2 Continuous Glucose Monitoring Academy

NCT06516640
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Continuous Glucose Monitoring Academy, Standard Education
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
8 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 9, 2026, 5:11 AM EDT
Completed Phase 1 Interventional

Pharmacokinetic Study of CYCLOSET ® 0.8 mg Tablets in Children and Adolescent Type 2 Diabetes Mellitus Subjects

NCT02078440
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Bromocriptine mesylate
Drug
Lead sponsor
VeroScience
Industry
Eligibility
10 Years to 17 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
5
States / cities
Phoenix, Arizona • New Haven, Connecticut • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Oct 9, 2026, 5:11 AM EDT