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ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:47 AM EDT

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Showing 337–360 of 625 matching trials from the live ClinicalTrials.gov search.
Conditions
CARDIOMETABOLIC CONDITIONS, Obesity, Pre-diabetes, Metabolic Syndrome, Type2diabetes, Hypertension, Dyslipidemias
Interventions
Base intervention, Augmented Intervention
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 74 Years
Enrollment
1,029 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri • Pittsburgh, Pennsylvania
Conditions
Weight Loss, Weight Gain, Weight Loss Maintenance
Interventions
TRE, Weight-Loss Maintenance Advice
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
25 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Obesity
Interventions
CP-741,952
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
5
States / cities
Ann Arbor, Michigan • Kalamazoo, Michigan • New York, New York + 2 more
Conditions
Sleep Apnea
Interventions
VI-0521, placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

CrossFit Exercise to Improve Glucose Control for Overweight and Obese Adults

NCT02185872
Conditions
Hyperglycemia
Interventions
High-Intensity Functional Training, Aerobic and Resistance Training
Other
Lead sponsor
Kansas State University
Other
Eligibility
18 Years to 40 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Manhattan, Kansas
Conditions
Obesity
Interventions
CagriSema (cagrilintide B and semaglutide I), CagriSema A
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 64 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Completed Not applicable Interventional Results available

Zonisamide for Weight Reduction in Obese Adults

NCT00275834
Conditions
Obesity
Interventions
Zonisamide
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Obesity
Interventions
Incentives for dietary self-monitoring and weight loss, Incentives for dietary self-monitoring, Incentives for weight loss
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
706 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Durham, North Carolina • Madison, Wisconsin
Conditions
Obesity, Insulin Resistance
Interventions
high-intensity interval training
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Accepts healthy volunteers

Postprandial Inflammation and Nuts (PIN) in Older Adults

NCT06348771
Conditions
Healthy Aging, Overweight and Obesity
Interventions
monounsaturated fatty acids (MUFA) peanut meal
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
55 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
New Brunswick, New Jersey
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity

NCT06842186
Conditions
Overweight and Obesity
Interventions
WVE-007
Drug
Lead sponsor
Wave Life Sciences USA, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Weight Reduction and Lifestyle Program in Older Adults

NCT00714506
Conditions
Functional Disability, Obesity, Physical Inactivity
Interventions
Diet and physical activity, Physical activity control
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
McKeesport, Pennsylvania
Conditions
Subcutaneous Fat Disorder
Interventions
10XB-101 Solution for Injection, 6.0%, Placebo Solution for Injection (no active ingredient)
Drug
Lead sponsor
10xBio, LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Rolling Meadows, Illinois • New Brighton, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Web-based Physical Activity Intervention to Promote Physical Activity

NCT05803304
Conditions
Cardiovascular Diseases
Interventions
PATH Intervention, Attention Control Intervention, Physical activity tracker, Dietary education
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Prader-Willi Syndrome
Interventions
Octreotide, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
5 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

Motivation for Exercise and Physical Activity Adherence

NCT04937205
Conditions
Obesity
Interventions
MOVE
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Obesity and Overweight
Interventions
NA-931, Tirzepatide, NA-931 150 mg + no Tirzepatide
Drug
Lead sponsor
Biomed Industries, Inc.
Industry
Eligibility
19 Years to 80 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 5 more
Conditions
Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
Interventions
Avocado, Control
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Las Vegas, Nevada
Conditions
Obesity, Obesity (Body Mass Index >30 kg/m2)
Interventions
Endoscopic Sleeve Gastroplasty (ESG), Fundal Mucosal Ablation
Device · Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Obesity, Overweight
Interventions
Bimagrumab, Tirzepatide, Bimagrumab Placebo, Tirzepatide Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
25
States / cities
Yuma, Arizona • Lake Forest, California • Long Beach, California + 22 more
Conditions
Obesity
Interventions
Placebo (Cohorts 1 and 2), PF-06882961 (Cohorts 1 and 2), Placebo (Cohort 3), PF-06882961 (Cohort 3)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
628 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
27
States / cities
Anniston, Alabama • Anaheim, California • Los Angeles, California + 23 more
Completed Not applicable Interventional Results available

Teaching Obesity Treatment Options to Adult Learners Trial

NCT03856320
Conditions
Obesity, Patient Education, Weight Loss
Interventions
Educational Video
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

The Relationship of TV Viewing to Energy Balance in Adults

NCT00622050
Conditions
Obesity, Overweight
Interventions
No TV viewing reduction, TV viewing reduction
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Hyperglycemia, Obesity Prevention
Interventions
powder shake with very low glycemic index, Ceral Breakfast
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
25 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona