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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Advance Directives Clear all
Completed Not applicable Interventional Results available

The Influence of Default Options in Advance Directives

NCT01346176
View directory record Official record
Conditions
Advance Care Planning
Interventions
Advance Directive Forms
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Community Engagement Activity for Advance Care Planning

NCT02575417
View directory record Official record
Conditions
Chronic Disease
Interventions
Conversation Game
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Advance Care Planning for Older Latinos With Chronic Illness

NCT06081660
View directory record Official record
Conditions
Patient Engagement, End of Life, Chronic Disease, Communication
Interventions
ACP-I Plan
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Trial of Video Education in Nursing Homes

NCT02612688
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Heart Failure, Pulmonary Disease, Chronic Obstructive
Interventions
ACP Video Program
Behavioral
Lead sponsor
Brown University
Other
Eligibility
65 Years and older
Enrollment
197,692 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Norcross, Georgia • Kennett Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2

NCT06384417
View directory record Official record
Conditions
Breast Cancer, Lung Cancer, Genito-Urinary Cancer, Colorectal Cancer, Gastric Cancer, Pancreatic Cancer, Liver Cancer, Head and Neck Cancer, Melanoma
Interventions
Hello for Cancer game, Table Topics game
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Choice Sets for Advance Directives

NCT02209038
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Expanded AD Choice, Expanded Life-sustaining Therapy Choice
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
15
States / cities
Camden, New Jersey • Philadelphia, Pennsylvania • Radnor, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Patient Perception of Video Advance Care Planning

NCT02692950
View directory record Official record
Conditions
Advanced Directive Planning
Interventions
Honor My Decisions Advance Care Planning Video, Post-video questionnaire
Other · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational

Cardiopulmonary Resuscitation (CPR) Video to Enhance Advance Care Planning in Advanced Upper Gastrointestinal Cancer Patients

NCT01105806
View directory record Official record
Conditions
Pancreas and Hepatobiliary Cancer Patients
Interventions
(CPR) video and questionnaires, cardiopulmonary resuscitation (CPR) narrative script and questionnaires
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Study of Default Options in Advance Directives

NCT01817686
View directory record Official record
Conditions
COPD, Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy, Idiopathic Pulmonary Fibrosis, Other Interstitial Lung Disease Without Curative Therapy, Congestive Heart Failure, NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year, Malignancy, Any Stage 3B or 4 Solid Tumor
Interventions
Comfort Default AD forms, Life Extension Default AD forms, Standard Default AD forms
Other
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Advance Care Planning: Communicating With Outpatients for Vital Informed Decision

NCT04660422
View directory record Official record
Conditions
Advanced Care Planning, Shared Decision Making, Video Decision Aids, Communication Skills, Advance Directives, Natural Language Processing, Covid19
Interventions
VitalTalk communication skills training, ACP Decisions Video Program, Intervention training:, Medical Record Review
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
65 Years and older
Enrollment
42,019 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Advance Directives Completion Rates and an Intervention to Address Health Literacy in a Clinic Population

NCT02702284
View directory record Official record
Conditions
Health Literacy
Interventions
Advance Directives, Advance Directives without assistance
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
51 Years and older
Enrollment
529 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 18, 2018 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Tailor Advance Directives

NCT00121004
View directory record Official record
Conditions
Dementia, Persistent Vegetative State, Terminally Ill
Interventions
Advance Directive Selection
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive

NCT00328055
View directory record Official record
Conditions
Aging
Interventions
AD-Easy (Advance Directive-Easy), AD-Standard (Advance Directive-Standard)
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2011 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Preparing Family Caregivers to Make Medical Decisions for Their Loved Ones

NCT02429479
View directory record Official record
Conditions
Neoplasms, Heart Failure, Kidney Diseases, Lung Diseases
Interventions
Making Your Wishes Known, Standard advance care planning
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intervention to Improve Expression of End of Life Preferences for Homeless Persons

NCT00546884
View directory record Official record
Conditions
Healthy
Interventions
MI condition, GI
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Behavioral Economics for Advance Care Options

NCT02100566
View directory record Official record
Conditions
End of Life Care
Interventions
Counseling (Care giver burden focus), Counseling (patient autonomy focus)
Behavioral
Lead sponsor
Ascension Health
Industry
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 6, 2026, 1:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations

NCT04612738
View directory record Official record
Conditions
Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness, Communication
Interventions
Hello (serious game), The Conversation Project (CP) Starter Kit, Table Topics (general conversation game)
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
79
States / cities
Athens, Alabama • Kingman, Arizona • Show Low, Arizona + 70 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support

NCT03323502
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
APPROACHES ACP Specialist Program, Standard of care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
47,396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Warsaw, Indiana • Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using an End-of-life Conversation Game to Engage Underserved Communities in Advance Care Planning

NCT03456921
View directory record Official record
Conditions
Advance Care Planning, Vulnerable Populations, Advance Directives, Terminal Illness
Interventions
End-of-life conversation game called "Hello"
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Sep 6, 2026, 1:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Choice of Diction's Effect

NCT04896411
View directory record Official record
Conditions
Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
Interventions
Alternative phrasing for no code, Standard of care for no code
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enabling Advance Directive Completion

NCT01746368
View directory record Official record
Conditions
Advance Directives
Interventions
The Nurse-Supported Advance Care Planning Intervention, Care-as-Usual
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
19 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 11, 2015 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational

An Exploratory Study of the Use of Five Wishes as a Tool for Advanced Care Planning in Young Adults With Metastatic, Recurrent, or Progressive Cancer or HIV Infection

NCT01445145
View directory record Official record
Conditions
Neoplasms
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
16 Years to 30 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Effect of an Advance Care Planning Intervention

NCT04852055
View directory record Official record
Conditions
Dementia
Interventions
Advance Care Planning Video
Behavioral
Lead sponsor
Brown University
Other
Eligibility
Not listed
Enrollment
2,364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Stillwater, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Comparison of a Web-based Advance Directive to a Standard Advance Directive

NCT03676426
View directory record Official record
Conditions
GI Cancer, Thoracic Cancer
Interventions
Web platform for advance care planning/advance directive, Standard advance directive
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2020 · Synced Sep 6, 2026, 1:23 PM EDT