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ClinicalTrials.gov public records Last synced Oct 31, 2026, 2:28 PM EDT

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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adverse Childhood Experience Clear all
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Physical Exercise for Augmenting Cognitive Health (PEACH)

NCT04922710
View directory record Official record
Conditions
Cognitive Aging, Adverse Childhood Experiences
Interventions
Home-based aerobic exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 31, 2026, 2:28 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Telephone-Based Care Coordination for Services Addressing Childhood Adversity

NCT07686614
View directory record Official record
Conditions
Health Services, Mental Health, Well-being
Interventions
Telephone-based Screening and Care Coordination
Behavioral
Lead sponsor
Paul Chung
Other
Eligibility
Not listed
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Resilience Clinic Evaluation

NCT05690256
View directory record Official record
Conditions
Early Life Adversity, Caregiver Stress
Interventions
Resilience Clinic, Enhanced primary care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 5 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
4
States / cities
Oakland, California • San Leandro, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity

NCT04606199
View directory record Official record
Conditions
Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms, Signs and Symptoms, Psychological Distress, Psychological
Interventions
Mindfulness-based intervention, up to 5 minutes 0-3 times/day
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)

NCT05201391
View directory record Official record
Conditions
Overweight and Obesity
Interventions
"Eat Right Now" (ERN) mobile application
Behavioral
Lead sponsor
Brown University
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adversity, Brain and Opioid Use Study

NCT06355778
View directory record Official record
Conditions
Opioid Use Disorder, Healthy
Interventions
Magnetic Resonance Imaging (MRI), Computer Tasks
Other · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Relationship of Adverse Childhood Experiences to Overweight and Obesity

NCT00632346
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Not listed
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 23 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2008 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional

Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services

NCT06769282
View directory record Official record
Conditions
Aggression Childhood, Teen Dating Violence
Interventions
Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 31, 2026, 2:28 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

BLOOM: Boldly Living outdOOrs for Mental Health

NCT05973123
View directory record Official record
Conditions
Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
Interventions
Group Nature Outings, Family Outings
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Years to 12 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Caregiver Adverse Childhood Experiences (ACEs) in Pediatric Primary Care

NCT05013138
View directory record Official record
Conditions
Child Development
Interventions
Training for ACEs and study procedures, Training on study procedures
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chamblee, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program

NCT06236100
View directory record Official record
Conditions
Substance-Related Disorders, Adverse Childhood Experiences
Interventions
Strengthening Families Program + Family Advocate, Strengthening Families Program
Behavioral
Lead sponsor
RTI International
Other
Eligibility
7 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tinton Falls, New Jersey
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth

NCT04096937
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Focus groups
Other
Lead sponsor
Gia Mudd
Other
Eligibility
10 Years to 99 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Hazard, Kentucky • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

NCT05665465
View directory record Official record
Conditions
Adverse Childhood Experiences, Nicotine Dependence, Cigarettes
Interventions
Nicotine nasal spray 0.5 mg, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Building Resilient Families

NCT05388864
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Three-Tier Model
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 11 Years
Enrollment
340 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Increasing Use of Earned Income Tax Credit (EITC) in New Mexico

NCT04961177
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
EITC & ACEs Training, EITC Outreach & Screening, Assistance with EITC
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise on Young Adult Women With ACEs: an Integrative Pilot Study

NCT03521401
View directory record Official record
Conditions
Life Experiences
Interventions
Exercise
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACEs, SIRT1, and Premature Vascular Aging in Humans

NCT07073352
View directory record Official record
Conditions
Adverse Childhood Experiences, Endothelial Dysfunction
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Active, not recruiting Not applicable Interventional

Perinatal Depression and Adverse Childhood Experiences: Prevention Trial

NCT05795114
View directory record Official record
Conditions
Perinatal Depression
Interventions
Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pediatric ACEs Screening and Resiliency Study

NCT04182906
View directory record Official record
Conditions
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection, Inflammatory Response, Self-regulation
Interventions
Care Coordination, Resiliency Clinic, Usual Care
Behavioral
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
3 Months to 11 Years
Enrollment
555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Brief Intervention for Chronic Pain and History of Stressful Experiences

NCT06983327
View directory record Official record
Conditions
Chronic Pain, Trauma, Adverse Childhood Experiences
Interventions
Trauma Focused Emotional Awareness and Expression Therapy (EAET)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examine the Effects of Mindfulness in Woman With a History of Child Adversity

NCT05255380
View directory record Official record
Conditions
Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms, Signs and Symptoms
Interventions
Mindfulness and compassion-based practices; approximately 5-10 minutes two times/day, Mindful awareness and reporting of current thoughts and feelings, 2 times/day
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 31, 2026, 2:28 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Adverse Childhood Experiences in Urogynecologic Patients

NCT03480477
View directory record Official record
Conditions
Pelvic Floor Disorders, Interstitial Cystitis, Urinary Incontinence
Interventions
ACE questionnaire
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
356 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 31, 2026, 2:28 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences

NCT06075446
View directory record Official record
Conditions
Child Abuse
Interventions
ACT Raising Safe Kids
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 31, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments

NCT06821035
View directory record Official record
Conditions
Adverse Childhood Experiences, Family Functioning
Interventions
Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
11 Years to 14 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 31, 2026, 2:28 PM EDT