- Conditions
- Memory, Cognitive Function
- Interventions
- Mixed spices, Placebo
- Dietary Supplement · Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Los Angeles, California
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Showing 1–24
of 52
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Age Related Cognitive Decline, Age Related Macular Degeneration
- Interventions
- Walnuts, habitual diet
- Dietary Supplement · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 63 Years to 79 Years
- Enrollment
- 708 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Cognitive Deterioration, Disorder of Aging
- Interventions
- aerobic training, Wait list
- Behavioral
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 20 Years to 75 Years
- Enrollment
- 233 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Mild Cognitive Impairment, Chronic Kidney Diseases
- Interventions
- Home-based walking exercise, Attention control
- Behavioral · Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • New York, New York
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 70 Years and older
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- Down Syndrome, Mild Cognitive Impairment
- Interventions
- Low Dose Nicotine (7mg), Moderate Dose Nicotine (14mg)
- Drug
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Aging
- Interventions
- Tai Chi, Guided autobiography, Qigong, Successful aging, Combination, Comparison
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 70 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Alzheimer Disease, Early Onset, Alzheimer Disease, Alzheimer Dementia, Mild Cognitive Impairment, Memory Disorders, Memory Loss, Memory Impairment, Memory Disorders, Age Related, Alzheimer Disease, Late Onset, Cognitive Impairment, Dementia, Mild, Dementia, Alzheimer Type, Cognitive Decline
- Interventions
- GammaSense Stimulation System (non-invasive, non-significant risk)
- Device
- Lead sponsor
- Cognito Therapeutics, Inc.
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Newton, Massachusetts
- Conditions
- Aging, Age-related Cognitive Decline, Obesity
- Interventions
- Strawberry, Placebo
- Dietary Supplement · Other
- Lead sponsor
- USDA Human Nutrition Research Center on Aging
- Federal
- Eligibility
- 55 Years to 75 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Age-Related Memory Disorders
- Interventions
- ispronicline (nicotinic acetylcholine receptor agonist)
- Drug
- Lead sponsor
- Targacept Inc.
- Industry
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 174 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005
- U.S. locations
- 15
- States / cities
- Mesa, Arizona • Peoria, Arizona • Denver, Colorado + 12 more
- Conditions
- Cognitive Decline, Age-Related Memory Disorders, Postoperative Complications, Age-Related Atrophy, Postoperative Cognitive Dysfunction
- Interventions
- Exercise Intervention
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Boston, Massachusetts
- Conditions
- Age-Related Memory Disorders
- Interventions
- Transdermal nicotine patch, Placebo transdermal patch
- Drug
- Lead sponsor
- National Institute on Aging (NIA)
- NIH
- Eligibility
- 55 Years to 90 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2008
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • Durham, North Carolina • Burlington, Vermont
- Conditions
- Age-related Cerebral White Matter Changes, Cognition Disorder
- Interventions
- remote ischemic conditioning
- Device
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 56 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Age-related Cognitive Decline
- Interventions
- MBSR, Exercise, Health Education
- Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 65 Years to 84 Years
- Enrollment
- 585 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2021
- U.S. locations
- 2
- States / cities
- San Diego, California • St Louis, Missouri
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Vascular Dementia, Lewy Body Disease, Lewy Body Dementia With Behavioral Disturbance (Disorder), Dementia, Mixed, Parkinson-Dementia Syndrome, Chronic Traumatic Encephalopathy, Huntington's Dementia, Wernicke Korsakoff Syndrome, Traumatic Brain Injury, Dementia, Multi-Infarct, Autism, Autism Spectrum Disorder, Autistic Behavior, Autistic Disorder, Current or Active State, Cadasil, LATE Limbic-predominant Age-related TDP-43 Encephalopathy
- Interventions
- Intravenous Bone Marrow Stem Cell (BMSC) Fraction, Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction, Near Infrared Light
- Procedure
- Lead sponsor
- MD Stem Cells
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 2
- States / cities
- Westport, Connecticut • Coral Springs, Florida
- Conditions
- Age Related Cognitive Decline
- Interventions
- PATH neurotraining, Orientation Discrimination
- Behavioral
- Lead sponsor
- Perception Dynamics Institute
- Industry
- Eligibility
- 55 Years to 75 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- La Jolla, California • Solana Beach, California
- Conditions
- Mobility Limitation, Cognitive Impairment
- Interventions
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Sham Transcranial Direct Current Stimulation (Sham tDCS), Active Transcranial Direct Current Stimulation (Active tDCS)
- Behavioral · Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 65 Years to 110 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 3
- States / cities
- Gainesville, Florida
- Conditions
- Alzheimer Disease, Hearing Loss, Cognitive Impairment
- Interventions
- Hearing Intervention, Health Education Intervention
- Device · Behavioral
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 55 Years to 75 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Age-related Cognitive Decline
- Interventions
- Delta-9-THC Low Dose, Placebo, Delta-9-THC Medium Dose
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Cognitive Decline, Mild
- Interventions
- Blueberry, Walking, Placebo, Stretching
- Dietary Supplement · Behavioral
- Lead sponsor
- Appalachian State University
- Other
- Eligibility
- 65 Years to 85 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Kannapolis, North Carolina
- Conditions
- Aging, Alzheimer Disease, Age-related Cognitive Decline
- Interventions
- Brain training, Paced breathing
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 50 Years to 70 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Age-related Cognitive Decline
- Interventions
- MRI
- Device
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 45 Years to 100 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2011
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Cardiovascular Risk Factors, Age-Related Cognitive Decline
- Interventions
- Tart cherry juice, Placebo
- Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 65 Years to 80 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Newark, Delaware