- Conditions
- Memory, Cognitive Function
- Interventions
- Mixed spices, Placebo
- Dietary Supplement · Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Los Angeles, California
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Showing 25–48
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- Conditions
- Hypertension
- Interventions
- High Intensity Interval Training (HIIT) Exercise
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 55 Years to 75 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Age-related Cognitive Decline
- Interventions
- Real-time strategy-based videogame training, Semantic Knowledge training
- Behavioral
- Lead sponsor
- The University of Texas at Dallas
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 58 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Age-related Cerebral White Matter Changes, Cognition Disorder
- Interventions
- remote ischemic conditioning
- Device
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 56 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Cardiovascular Risk Factors, Age-Related Cognitive Decline
- Interventions
- Tart cherry juice, Placebo
- Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 65 Years to 80 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Age Related Cognitive Decline, Age Related Macular Degeneration
- Interventions
- Walnuts, habitual diet
- Dietary Supplement · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 63 Years to 79 Years
- Enrollment
- 708 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Age-related Cognitive Decline
- Interventions
- MBSR, Exercise, Health Education
- Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 65 Years to 84 Years
- Enrollment
- 585 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2021
- U.S. locations
- 2
- States / cities
- San Diego, California • St Louis, Missouri
- Conditions
- Intermittent Fasting, Aging
- Interventions
- Time restricted eating
- Other
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 55 Years to 80 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Vascular Dementia, Lewy Body Disease, Lewy Body Dementia With Behavioral Disturbance (Disorder), Dementia, Mixed, Parkinson-Dementia Syndrome, Chronic Traumatic Encephalopathy, Huntington's Dementia, Wernicke Korsakoff Syndrome, Traumatic Brain Injury, Dementia, Multi-Infarct, Autism, Autism Spectrum Disorder, Autistic Behavior, Autistic Disorder, Current or Active State, Cadasil, LATE Limbic-predominant Age-related TDP-43 Encephalopathy
- Interventions
- Intravenous Bone Marrow Stem Cell (BMSC) Fraction, Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction, Near Infrared Light
- Procedure
- Lead sponsor
- MD Stem Cells
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 2
- States / cities
- Westport, Connecticut • Coral Springs, Florida
- Conditions
- Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
- Interventions
- Cognitive Training, Computerized Cognitive Stimulation
- Behavioral
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 7,600 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2026
- U.S. locations
- 7
- States / cities
- Gainesville, Florida • Jacksonville, Florida • Sarasota, Florida + 3 more
- Conditions
- Age-related Memory Disorders, Mood Disorders
- Interventions
- Omega-3 fatty acid, Blueberry powder, Placebo oil, Placebo powder
- Dietary Supplement · Other
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 62 Years to 80 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Aging
- Interventions
- Tai Chi, Guided autobiography, Qigong, Successful aging, Combination, Comparison
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 70 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Age-related Cognitive Decline
- Interventions
- MRI
- Device
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 45 Years to 100 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2011
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Aging, Alzheimer Disease, Age-related Cognitive Decline
- Interventions
- Brain training, Paced breathing
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 50 Years to 70 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Age-related Cognitive Decline
- Interventions
- Vortioxetine 10 mg, Cognitive training program
- Drug · Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 129 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Cognition Disorders, Brain Pathology, Physical Disability, Physical Activity, Aging
- Interventions
- Aerobic Activity, Resistance Training, Yoga, Health Education
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 65 Years to 80 Years
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 70 Years and older
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- Age-related Cognitive Decline
- Interventions
- Multi-tasking Training
- Behavioral
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 60 Years to 75 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Age-Related Memory Disorders
- Interventions
- ispronicline (nicotinic acetylcholine receptor agonist)
- Drug
- Lead sponsor
- Targacept Inc.
- Industry
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 174 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005
- U.S. locations
- 15
- States / cities
- Mesa, Arizona • Peoria, Arizona • Denver, Colorado + 12 more
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Boston, Massachusetts
- Conditions
- Mild Cognitive Impairment, Age-related Cognitive Decline
- Interventions
- Music Training I
- Behavioral
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 268 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Age Related Cognitive Decline, Alzheimer's Disease, Vascular Dementia, Endothelial Dysfunction, Executive Dysfunction
- Interventions
- Omega 3 PUFA, Placebo
- Drug
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 75 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2021
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Cognitive Decline, Age-Related Memory Disorders, Postoperative Complications, Age-Related Atrophy, Postoperative Cognitive Dysfunction
- Interventions
- Exercise Intervention
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Age-Related Cognitive Decline, Age-Related Memory Disorders
- Interventions
- DHA (nutritional supplement) or placebo
- Dietary Supplement
- Lead sponsor
- dsm-firmenich Switzerland AG
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 485 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 14
- States / cities
- Mesa, Arizona • San Diego, California • Vista, California + 11 more