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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Age-related Hearing Impairment Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Hearing Health for Korean American Older Adults With Mild Cognitive Impairment

NCT06068933
View directory record Official record
Conditions
Age-related Hearing Impairment, Personal Communication, Mild Cognitive Impairment
Interventions
K-HEARS Intervention, K-HEARS Sound Amplifier Intervention
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Unilateral vs Bilateral Hearing Aids for the Treatment of Age-related Hearing Loss

NCT04739436
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing amplification
Device
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Durham, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jul 23, 2026, 10:57 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss

NCT04513782
View directory record Official record
Conditions
Healthy Individuals, Hearing Loss, Central
Interventions
Audiological Assessments
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)

NCT06580847
View directory record Official record
Conditions
Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
Interventions
Group Singing, Audiobook Club
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions

NCT03442296
View directory record Official record
Conditions
Age-related Hearing Impairment 1, Personal Communication
Interventions
Baltimore HEARS, Baltimore HEARS
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 100 Years
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound

NCT07304024
View directory record Official record
Conditions
Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality, Hearing Disability, Hearing Disorder, Hearing Disorders, Hearing Impairment, Sensorineural, Hearing Handicap, Hearing Impaired, Hearing Impairment, Hearing Loss, Central Auditory Disease, Noise Exposure, Noise Induced Hearing Loss, Noise-Induced Hearing Loss, Sound Perception, Myelin Degeneration, Myelinopathy, Myelin Integrity, Remyelination, Hidden Hearing Loss, Cocktail Party Skill, Cocktail Party Syndrome, CAPD, Age Problem
Interventions
Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound, Placebo - Placebo
Combination Product · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 65 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Baltimore HEARS Pilot Study

NCT02045511
View directory record Official record
Conditions
Age-related Hearing Impairment 1, Personal Communication
Interventions
Baltimore HEARS, Baltimore HEARS
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Early Age-Related Hearing Loss Investigation (EARHLI)

NCT06174038
View directory record Official record
Conditions
Alzheimer Disease, Hearing Loss, Cognitive Impairment
Interventions
Hearing Intervention, Health Education Intervention
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
55 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Phase 4 Interventional Results available

Treating Hearing Loss to Improve Mood and Cognition in Older Adults

NCT03321006
View directory record Official record
Conditions
Hearing Loss, Depression
Interventions
Phonak Audeo B-R 90 hearing aid device (Active), Duloxetine or escitalopram, Audeo B-R 90 hearing aid device (Sham)
Device · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2021 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Assessment of e-Audiology for Providing Clinical Services and Support

NCT04048460
View directory record Official record
Conditions
Hearing Loss, Age-Related, Presbycusis, Bilateral, Hearing Disability
Interventions
Delivery of hearing healthcare through eAudiology application
Device
Lead sponsor
University of South Florida
Other
Eligibility
70 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Jul 23, 2026, 10:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Age-Related Hearing Loss Investigation Pilot Study

NCT05970211
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Audeo Lumity Receiver in Canal Hearing Aid
Device
Lead sponsor
University of South Florida
Other
Eligibility
55 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Early Phase 1 Interventional Results available

Workshops for Veterans With Vision and Hearing Loss

NCT01109576
View directory record Official record
Conditions
Deafness, Blindness
Interventions
DSL Workshop
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
55 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Decatur, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 28, 2015 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss

NCT07192757
View directory record Official record
Conditions
Presbycusis
Interventions
transcutaneous auricular vagus nerve stimulation, Sham Control
Device
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hearing for Communication and Resident Engagement

NCT04575051
View directory record Official record
Conditions
Hearing Loss, Age-Related
Interventions
Consult Model, Engage Model
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
684 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Stem Cell Ophthalmology Treatment Study II

NCT03011541
View directory record Official record
Conditions
Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease, Optic Neuropathy, Nonarteritic Ischemic Optic Neuropathy, Optic Atrophy, Optic Nerve Disease, Glaucoma, Leber Hereditary Optic Neuropathy, Blindness, Vision Loss Night, Vision Loss Partial, Vision, Low, Retinopathy, Maculopathy, Macular Degeneration, Retina Atrophy
Interventions
Arm 1
Procedure
Lead sponsor
MD Stem Cells
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
2
States / cities
Westport, Connecticut • Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Hearing Healthcare Assessment in Rural Communities

NCT05786794
View directory record Official record
Conditions
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Interventions
Patient Navigation Program for Hearing Health Care
Behavioral
Lead sponsor
Matthew Bush, MD
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
9
States / cities
Campbellsville, Kentucky • Campton, Kentucky • Elkton, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 10:57 AM EDT
Enrolling by invitation Not applicable Interventional

Hearing Health Equity Through Accessible Research and Solutions for Korean Americans

NCT06803394
View directory record Official record
Conditions
Age-related Hearing Impairment, Personal Communication, Hearing Impairment, Hearing Loss, Community-dwelling Seniors, Korean
Interventions
K-HEARS Intervention, K-HEARS Sound Amplifier Intervention
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jul 23, 2026, 10:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
View directory record Official record
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2005 · Synced Jul 23, 2026, 10:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Hearing Loss and Communication Needs in a Group Care Setting for Older Adults

NCT04659967
View directory record Official record
Conditions
Age-related Hearing Loss
Interventions
Virtual Training
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • West Springfield, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Phase 2 Interventional Results available

Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss

NCT02345031
View directory record Official record
Conditions
Age-Related Hearing Loss
Interventions
AUT00063, Placebo
Drug
Lead sponsor
Autifony Therapeutics Limited
Industry
Eligibility
50 Years to 89 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
13
States / cities
Sacramento, California • Colorado Springs, Colorado • Boca Raton, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Phase 1 Interventional

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

NCT01518920
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
PF-04958242, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
50 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
11
States / cities
Anaheim, California • New Haven, Connecticut • South Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Jul 23, 2026, 10:57 AM EDT
Recruiting No phase listed Observational

Adaptive Optics Imaging of Outer Retinal Diseases

NCT05355415
View directory record Official record
Conditions
Retinal Degeneration, Age-Related Macular Degeneration, Retinitis Pigmentosa, Hydroxychloroquine Retinopathy, Usher Syndromes, Late-Onset Retinal Degeneration, Cone Dystrophy, Cone Rod Dystrophy, Rod Cone Dystrophy, Rod Dystrophy
Interventions
Adaptive optics imaging
Device
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
21 Years and older
Enrollment
100 participants
Timeline
2021 – 2028
U.S. locations
2
States / cities
Bethesda, Maryland • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 23, 2026, 10:57 AM EDT
Completed Phase 1 Interventional

FX-322 in Adults With Age-Related Sensorineural Hearing Loss

NCT04601909
View directory record Official record
Conditions
Presbycusis, Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
66 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Sarasota, Florida • Omaha, Nebraska • Amherst, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Jul 23, 2026, 10:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sight and Hearing Investigation Into Effects on Delirium

NCT06176625
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium, Delirium in Old Age, Delirium of Mixed Origin, Delirium With Dementia, Delirium on Emergence, Delirium, Cause Unknown, Delirium Superimposed on Dementia, Delirium Confusional State, Delirium;Non Alcoholic, Hearing Loss, Bilateral, Hearing Loss, Sensorineural, Hearing Loss, Functional, Hearing Loss, High-Frequency, Hearing
Interventions
Communication Signage, Amplifier Use
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 23, 2026, 10:57 AM EDT