Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 1,603 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Analysis in Human Sulfur Amino Acid Deficiency

NCT00253760
Conditions
Oxidative Stress, Diabetes, Heart Diseases
Interventions
dietary amino acids; cysteine and methionine
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Buck Institute Ketone Ester RCT

NCT05585762
Conditions
Tolerance, Safety Issues, Aging
Interventions
Ketone ester, Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Novato, California
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Combination Gerotherapeutic Interventions for Healthspan Improvement

NCT07475546
Conditions
Healthspan Improvement, Aging, Longevity
Interventions
Rapamycin, Naltrexone, Metformin, NAD+, GSH, Infinite Supplement, Placebo/control, B12, Intervention: Guided Meditation Program, Control: Podcast Listening Activity, Control: Standard Exercise Regimen, Intervention: Structured Exercise Program
Drug · Dietary Supplement · Behavioral
Lead sponsor
AgelessRx
Industry
Eligibility
60 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Skin Aging
Interventions
Investigational Facial Serum #1, Investigational Facial Serum #2, Investigational Facial Serum #3
Other
Lead sponsor
Victoria Collotta
Industry
Eligibility
35 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Needham, Massachusetts
Conditions
Skin Hydration, Skin Aging
Interventions
Truology A2, Truology C-Boost, Truology Barrier Restore
Dietary Supplement
Lead sponsor
Truology
Industry
Eligibility
35 Years to 55 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
Sarcopenia, Aging
Interventions
Exercise training
Other
Lead sponsor
Purdue University
Other
Eligibility
60 Years to 80 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
West Lafayette, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Adults With PTSD

NCT05365607
Conditions
Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction
Interventions
NightWare, Sham NightWare
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Estrogen Use in Protection From Cognitive Decline

NCT00097058
Conditions
Aging, Menopause
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Stanford, California
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Quercetin on Metabolic Health

NCT05297032
Conditions
Quercetin, Lipid Metabolism, Aging
Interventions
Quercetin Phytosome
Dietary Supplement
Lead sponsor
Thorne HealthTech, Inc
Industry
Eligibility
20 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Summerville, South Carolina
Completed Not applicable Interventional

Macular Degeneration and Aging Study

NCT02224963
Conditions
Age-related Macular Degeneration
Interventions
Preventive Problem-Solving Training, Life and Health Review
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
Rochester, New York
Completed Phase 2 Interventional Accepts healthy volunteers

Healthy Living as You Age

NCT00379093
Conditions
Alcohol Related Disorders, Alcohol Drug Interactions
Interventions
Brief advice
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
55 Years and older
Enrollment
631 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Intrinsic Aging of Skin
Interventions
Juvéderm Ultra, Cosmoderm 1
Device
Lead sponsor
Steven Fagien
Other
Eligibility
25 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boca Raton, Florida
Conditions
Aging, Frailty, Osteoporosis
Interventions
testosterone
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years and older · Male only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Farmington, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)

NCT01641263
Conditions
Depression
Interventions
Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Enrolling by invitation Not applicable Interventional

Promoting Aging and Thriving With HIV

NCT07192419
Conditions
HIV (Human Immunodeficiency Virus), Geriatric, Geriatric Assessment, HIV, HIV - Human Immunodeficiency Virus
Interventions
Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Indianapolis, Indiana
Withdrawn Not applicable Interventional Accepts healthy volunteers

Trunk Control Training and Walking in Older Adults

NCT06782919
Conditions
Chronic Low Back Pain (CLBP), Aging
Interventions
Trunk control training
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

UCLA Fitness and Memory Study of Activity In Mild Cognitive Impairment (AIM)

NCT02001441
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 89 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
Interventions
Not listed
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 64 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Recruiting No phase listed Observational Accepts healthy volunteers

Glucose Variability and Cognition in Prediabetes

NCT04201600
Conditions
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, Functional Status, PreDiabetes, Aging, Depression
Interventions
Continuous Glucose Monitoring System (CGMS)
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
COVID-19
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Dementia
Interventions
PLAN, Standard of Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Bayside, New York • Annandale, Virginia
Conditions
HIV Infection
Interventions
exercise training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
3
States / cities
Decatur, Georgia • Baltimore, Maryland • Salem, Virginia
Recruiting Not applicable Interventional Accepts healthy volunteers

BID WM Digital Intervention in Aging

NCT06918704
Conditions
Working Memory, Inhibitory Control, Mild Cognitive Impairment (MCI), Aging
Interventions
Coherence, Worder
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Conditions
Aging
Interventions
SkinPen Precision
Device
Lead sponsor
Bellus Medical, LLC
Industry
Eligibility
50 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Dallas, Texas