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Showing 1–24 of 1,615 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Temporal Genomics Mechanisms Underlying Disease and Aging

NCT03637751
Conditions
Gene Expression in Response to Acute Stress
Interventions
Behavioral, Control condition
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 25 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Aging, Depression, Cognitive Symptoms
Interventions
Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation)
Behavioral · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Juvéderm® VOLUMA XC Injectable Gel for Cheek Augmentation

NCT00978042
Conditions
Mid-facial Volume Deficit Related to Aging
Interventions
Juvéderm® VOLUMA XC
Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years to 65 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Completed No phase listed Observational Accepts healthy volunteers

A Study of Brain Aging in Vietnam War Veterans

NCT01687153
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 90 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
19
States / cities
Sun City, Arizona • Irvine, California • La Jolla, California + 14 more
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Women's Healthy Aging and Menopause; (WHAM)

NCT07314827
Conditions
Meditation, Health Education
Interventions
Transcendental Meditation (TM), Women's Health Education (WHE)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
50 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Conditions
Diabetes Mellitus, Aging
Interventions
Motivational support, PALS - Physical activity for lifetime success
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
50 Years and older
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy Evaluation of the Xerf Device for Aesthetic Treatments

NCT07585591
Conditions
Facial Aging, Facial Skin Laxity, Submental and Neck Skin Laxity
Interventions
Noninvasive dual-frequency monopolar radiofrequency
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
22 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
4
States / cities
Naperville, Illinois • Hunt Valley, Maryland • Montclair, New Jersey + 1 more
Completed No phase listed Observational Accepts healthy volunteers

Age-Related Changes in Stress Hormone Regulation

NCT00018369
Conditions
Physiological Processes, Aging
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alzheimer Disease, Dementia, Alzheimer's Disease (Incl Subtypes), Aging
Interventions
Primary Care Team Advance Care Planning With People with Alzheimer's Disease or a Related Dementia Training, Care as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Sepsis, Influenza
Interventions
Not listed
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Murray, Utah
Conditions
Aging
Interventions
NanoSilk Cosmo
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Radiesse® Dermal Filler for Hand Treatment

NCT01832090
Conditions
Aging Hands
Interventions
Radiesse® Injectable Dermal Filler
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
6
States / cities
San Diego, California • Vista, California • Garden City, New York + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of "Smart Wheelchairs" to Provide Independent Mobility to Visual and Mobility Impairments

NCT00333762
Conditions
Blindness, Spinal Cord Injury
Interventions
Smart Power Assistance Module (SPAM), Smart Wheelchair Component System (SWCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
2
States / cities
Decatur, Georgia • Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Cluster Resistance Training and Older Adults

NCT06588842
Conditions
Healthy Aging
Interventions
Cluster Set Resistance Training, Traditional Set Resistance Training
Other
Lead sponsor
University of Miami
Other
Eligibility
55 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Coral Gables, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Technology-assisted Vocal Exercise for Older Adults

NCT03015870
Conditions
Aging
Interventions
Vocal exercise with real-time feedback, Vocal exercise with recording
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Champaign, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using TMS to Increase Executive Function in Older Adults

NCT02767323
Conditions
Aging
Interventions
rTMS, Sham rTMS
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Amino Acids on Regional Lipid Metabolism

NCT01150188
Conditions
Hypertriglyceridemia
Interventions
Amino acids, Placebo
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
50 Years to 75 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Type 2 Diabetes, Muscle Atrophy, Aging, Sedentary Behavior, Pre-diabetes
Interventions
Bed rest
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Obesity
Interventions
Vibegron, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Retinol on Human Skin Aging in East Asian Descent

NCT02906566
Conditions
Intrinsic Aging of Skin
Interventions
Retinol, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Redwood City, California
Conditions
Blindness
Interventions
Visual
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Decatur, Georgia
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neuromodulation Effects in Older Adults

NCT06665022
Conditions
Cognitive Impairment, Cognitive Decline
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting No phase listed Observational Accepts healthy volunteers

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

NCT07099053
Conditions
Aging
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 110 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Telehealth for Diabetes Self-Management

NCT00194805
Conditions
Diabetes, Aging
Interventions
Telehealth for Diabetes Self Management, Telehealth for Diabetes Self Management
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
60 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Seattle, Washington