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ClinicalTrials.gov public records Last synced Oct 24, 2026, 1:21 AM EDT

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Showing 289–312 of 1,647 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aging Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Impact of a Sleep Debt in Middle-Aged and Older Adults

NCT00817700
View directory record Official record
Conditions
Sleep Restriction
Interventions
Sleep restriction
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 24, 2026, 1:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults

NCT03803566
View directory record Official record
Conditions
Aging
Interventions
Pegboard practice, Force control practice
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 89 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 24, 2026, 1:21 AM EDT
Completed No phase listed Observational

Development and Decline of Brain and Cognition Through the Life Span

NCT00880451
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Regular Beef Consumption and Protein Density of the Diet on Training-induced Gains in Muscle Strength and Performance in Healthy Adults

NCT03029975
View directory record Official record
Conditions
Aging
Interventions
Resistance Training Exercise, Beef Protein Consumption
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 64 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 24, 2026, 1:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Connection for Latinos Caring for a Loved One With Dementia

NCT04593628
View directory record Official record
Conditions
Social Isolation, Loneliness
Interventions
Connect for Caregivers
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2022 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Enhancement Training Towards Elders Resilience to Aging

NCT03197454
View directory record Official record
Conditions
Age-related Cognitive Decline
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years and older
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Iowa City, Iowa • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles

NCT06086795
View directory record Official record
Conditions
Lipoproteins, Inflammatory Response
Interventions
Whole eggs, Egg yolks, Egg whites
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 24, 2026, 1:21 AM EDT
Completed No phase listed Observational

Tenofovir, Emtricitabine, Efavirenz and Atazanavir Pharmacokinetics in the Aging HIV-Infected Population

NCT01180075
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
tenofovir/emtricitabine/efavirenz (TDF/FTC/EFV), tenofovir/emtricitabine (TDF/FTC), Atazanavir (ATV), Ritonavir, Phlebotomy
Drug · Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Spinal Excitation to Enhance Mobility

NCT03667573
View directory record Official record
Conditions
Aging
Interventions
tsDCS Dosage (A), tsDCS Dosage (B), textured shoe insoles
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

REACH Pilot Study (Rehabilitation Enhancing Aging Through Connected Health)

NCT02580409
View directory record Official record
Conditions
Mobility Limitation
Interventions
Exercise Intervention
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
65 Years to 95 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 24, 2026, 1:21 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes

NCT07060898
View directory record Official record
Conditions
Aging, Cognitive Decline, Brain Fog, Cognitive Function
Interventions
Active Product, Placebo Product
Dietary Supplement
Lead sponsor
Amazentis SA
Industry
Eligibility
40 Years and older
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Encinitas, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 24, 2026, 1:21 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Isa-Pom-Dex in Elderly/Frail Subjects With RRMM

NCT05911321
View directory record Official record
Conditions
Multiple Myeloma, Relapse, Refractory, Aging, Co-morbidity
Interventions
Isatuximab, Pomalidomide, Dexamethasone
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Supplements and Exercise in Aging Adults

NCT00761553
View directory record Official record
Conditions
Exercise
Interventions
Dietary supplements with exercise, Dietary supplement without exercise
Other · Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
55 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Homeostatic Sleep Regulation in Older Persons

NCT00601445
View directory record Official record
Conditions
Healthy, Aging
Interventions
Amount of sleep and wake
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2008 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Exercise Poles on Older Adults During Exercise Walking

NCT00037167
View directory record Official record
Conditions
Movement Disorders, Aging
Interventions
Exercise poles
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
65 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 9, 2009 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Physical Performance Measures for Manual Wheelchair Users

NCT00011544
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Performance Measure
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 79 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2000
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aquatic Exercise for Cognition and Mobility in Older Adults

NCT05501249
View directory record Official record
Conditions
Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady, Mobility Limitation
Interventions
Aquatic Integrated Cognitive Motor Training
Behavioral
Lead sponsor
Emily Dunlap
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 24, 2026, 1:21 AM EDT
Recruiting No phase listed Observational

Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry

NCT05556928
View directory record Official record
Conditions
Multiple Myeloma, Amyloidosis, Plasma Cell Leukemia
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
5,000 participants
Timeline
2020 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Changes With Game Training in Aging

NCT02490137
View directory record Official record
Conditions
Aging, Dementia
Interventions
Race Car Video Game
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Physical Therapists - Recommending EnhanceFitness to Expand Reach

NCT03139461
View directory record Official record
Conditions
Physical Activity, Aging
Interventions
PT-REFER Capacity-building Toolkit
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Phase 2 Interventional

Social Connections and Healthy Aging (The Senior Connection)

NCT01408654
View directory record Official record
Conditions
Suicidal Ideation, Depression
Interventions
Peer Companionship
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 24, 2026, 1:21 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Assessing the Feasibility of Multi-modal Biosensing for Monitoring Mobility and Cognition in Older Adults

NCT07217951
View directory record Official record
Conditions
Chronic Stress, Systemic Inflammation, Mobility and Independence
Interventions
Eutectogel Sensors and Microneedle Patches
Device
Lead sponsor
Tufts University
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 24, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrient Sensing & Signaling in Aging Muscle

NCT02999802
View directory record Official record
Conditions
Nutrient Sensing
Interventions
Exercise
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
65 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Oct 24, 2026, 1:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurobiological Mechanisms of Aging and Stress on Prospective Navigation

NCT03896529
View directory record Official record
Conditions
Aging, Anxiety, Memory Impairment
Interventions
Anticipatory psychological stress
Behavioral
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
65 Years to 80 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 24, 2026, 1:21 AM EDT