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Showing 1321–1344 of 1,650 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Speech Perception With High Cognitive Demand

NCT04698356
Conditions
Speech Intelligibility, Aging
Interventions
Auditory-cognitive training paradigm
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 30 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
College Park, Maryland
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ovarian Function Following Intraovarian Injection of PRP

NCT04278313
Conditions
Diminished Ovarian Reserve, Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PRP - Platelet Rich Plasma, PPP - Platelet Poor Plasma
Procedure
Lead sponsor
Center for Human Reproduction
Other
Eligibility
21 Years to 44 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Scarring, Skin Aging
Interventions
Excel V™ Laser & Micro-Lens Array Attach
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Brisbane, California • Sacramento, California
Active, not recruiting Not applicable Interventional

Far Red Light to Improve Functioning in PAD

NCT06165016
Conditions
Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
Interventions
Far red light therapy, Sham light therapy
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Recruiting Phase 2 Interventional Accepts healthy volunteers

Study of Healthy Aging and Physical Function With Elamipretide

NCT07275424
Conditions
Aging, Healthy
Interventions
Elamipretide will be supplied as a sterile 5.0 mL single-patient, multi-dose glass vial containing 3.75 mL of elamipretide solution (elamipretide [80 mg/mL], phosphate buffer, and benzyl alcohol)
Drug
Lead sponsor
David Marcinek
Other
Eligibility
65 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Completed No phase listed Observational

Lactate for Energy and Neurocognition

NCT05207397
Conditions
Healthy Aging, Alzheimer Disease
Interventions
Lactate infusion
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 95 Years
Enrollment
24 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Polypharmacy
Interventions
Educational brochure for deprescribing
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
50 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Aging, Balance Deficits
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham
Device
Lead sponsor
Weinberg Medical Physics LLC
Industry
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Diabetes Mellitus, Aging
Interventions
Motivational support, PALS - Physical activity for lifetime success
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
50 Years and older
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
Interventions
Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years to 90 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Completed Phase 4 Interventional Accepts healthy volunteers

Memory and Mental Health in Aging

NCT02988908
Conditions
Memory
Interventions
Donepezil, Placebos
Drug
Lead sponsor
Stanford University
Other
Eligibility
55 Years to 90 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2007
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Results available

Using Peer Mentors to Deliver Depression Care

NCT02261818
Conditions
Depression
Interventions
Meetings with peer mentors
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Smokers, Former Smokers
Interventions
lamivudine, rapamycin, Exercise Regimen, Spermidine
Drug · Behavioral · Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Not listed No phase listed Observational Accepts healthy volunteers

Effects of Age and Exercise on Blood Pressure Regulation

NCT00319397
Conditions
Cardiovascular Disease, Aging
Interventions
Exercise-Training Program
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Prepare for Your Diabetes Care

NCT05263310
Conditions
Type 2 Diabetes Mellitus With Hypoglycemia, Aging, Patient Activation
Interventions
Prepare for Your Diabetes Care, Usual Care
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
75 Years and older
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Oakland, California
Conditions
Vascular Diseases
Interventions
Rhythmic Handgrip Exercise, Chronic Exercise Training
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Aging, Facial Aging
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

IH, Brain Health, and T2D

NCT07173543
Conditions
Type 2 Diabetes, Aging
Interventions
Intermittent Hypoxia 1 (IH1), Intermittent Hypoxia 2 (IH2), SHAM - normoxia
Other
Lead sponsor
Darren P Casey
Other
Eligibility
60 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 2 Interventional Accepts healthy volunteers

Shingles: Immune Effects of Tai Chi

NCT00118885
Conditions
Aging, Herpes Zoster
Interventions
Tai Chi Chih
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 90 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Aging, Postmenopause
Interventions
Mitoquinone (MitoQ), Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
60 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Fort Collins, Colorado
Conditions
Frailty
Interventions
Center based attention (stretching only) control, Center based HIIT, Home based HIIT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Kansas City, Missouri
Not listed Not applicable Interventional Accepts healthy volunteers

Hydraulic Resistance and Older Adults

NCT06353438
Conditions
Aging, Fall, Old Age; Debility, Muscle Weakness
Interventions
Exercise Program
Other
Lead sponsor
College of Staten Island, the City University of New York
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Brooklyn, New York
Completed No phase listed Observational Accepts healthy volunteers

Vaccine Efficacy in Diabetic and Elderly Patients

NCT02675608
Conditions
Inflammation
Interventions
Influenza Virus Vaccine
Biological
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
New Orleans, Louisiana