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ClinicalTrials.gov public records Last synced Nov 1, 2026, 5:03 PM EST

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Showing 1369–1392 of 1,650 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aging Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

The Role of the Locus Coeruleus in Age-related Distractibility

NCT05574634
View directory record Official record
Conditions
Aging, Alzheimer Disease
Interventions
Tablet based adaptive multimodal attention practice program, Tablet based adaptive criterion task practice program
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Nov 1, 2026, 5:03 PM EST
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease

NCT02380573
View directory record Official record
Conditions
Mild Cognitive Impairment, MCI, Aging, Alzheimer's Disease, AD
Interventions
Methylene Blue, FD&C Blue # 2, Phenazopyridine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
45 Years to 89 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Nov 1, 2026, 5:03 PM EST
Suspended Not applicable Interventional Accepts healthy volunteers

Light Exposure to Treat Sleep Disruption in Older People

NCT00427323
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
Interventions
light exposure
Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Nov 1, 2026, 5:03 PM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging

NCT06804759
View directory record Official record
Conditions
Skin Aging
Interventions
Investigational Facial Serum #1, Investigational Facial Serum #2, Investigational Facial Serum #3
Other
Lead sponsor
Victoria Collotta
Industry
Eligibility
35 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Needham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Nov 1, 2026, 5:03 PM EST
Completed No phase listed Observational

Variability of Physical Assessments in an Older Population That is Overweight or Obese

NCT05174923
View directory record Official record
Conditions
Obesity, Aging
Interventions
Short Performance Physical Battery (SPPB Test), 30 Second Chair Stand Test (30CST), Hand grip dynamometry
Behavioral
Lead sponsor
Versanis Bio, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Jacksonville, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Ankle Exoskeleton Assistance for Walking Across the Life Span

NCT04033146
View directory record Official record
Conditions
Aging
Interventions
Ankle Exoskeleton Assistance
Device
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Nov 1, 2026, 5:03 PM EST
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial

NCT07871162
View directory record Official record
Conditions
Aging, Endothelial Dysfunction, Cellular Senescence
Interventions
Fisetin, Placebo
Dietary Supplement · Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
65 Years and older
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional

Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing

NCT06660979
View directory record Official record
Conditions
Aging
Interventions
Reinforcement learning
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Nov 1, 2026, 5:03 PM EST
Not listed Not applicable Interventional

Exercise Adherence Among Older Adults With Osteoarthritis

NCT00421681
View directory record Official record
Conditions
Osteoarthritis
Interventions
Fit and Strong! Exercise Program
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2009 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional Results available

Engage Coaching for Latinos

NCT04875065
View directory record Official record
Conditions
Social Isolation, Loneliness, Caregiver Burnout
Interventions
Engage coaching
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
40 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Nov 1, 2026, 5:03 PM EST
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF)

NCT00948857
View directory record Official record
Conditions
Premature Ovarian Failure
Interventions
Dehydroepiandrosterone, Placebo
Dietary Supplement
Lead sponsor
David H. Barad
Other
Eligibility
21 Years to 39 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Nov 1, 2026, 5:03 PM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

An Investigation of a Multi-Function Skincare Product to Improve Aging, Eczema, and Acne Outcomes

NCT05873933
View directory record Official record
Conditions
Acne, Eczema, Skin Aging
Interventions
Hemptress Oil
Other
Lead sponsor
Hemptress
Industry
Eligibility
21 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults

NCT06203392
View directory record Official record
Conditions
Aging, Musculoskeletal Diseases
Interventions
Very low carbohydrate ketogenic diet, Mediterranean diet
Other
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Nov 1, 2026, 5:03 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women

NCT07222111
View directory record Official record
Conditions
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
Interventions
Dried plums
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
60 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Nov 1, 2026, 5:03 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Nutrition and Exercise for Sarcopenia

NCT00872911
View directory record Official record
Conditions
Sarcopenia
Interventions
Amino acids, Exercise
Dietary Supplement · Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
65 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Nov 1, 2026, 5:03 PM EST
Completed Phase 2Phase 3 Interventional Results available

Enhancing Fitness in Older Pre-diabetic Veterans

NCT00594399
View directory record Official record
Conditions
Impaired Glucose Tolerance, Obesity, Diabetes
Interventions
Physical Activity Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Nov 1, 2026, 5:03 PM EST
Recruiting Phase 1 Interventional

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

NCT07290244
View directory record Official record
Conditions
Open Angle Glaucoma (OAG), NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Interventions
ER-100 epigenetic therapy
Genetic
Lead sponsor
Life Biosciences Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
4
States / cities
Glendale, California • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Aerobic and Resistance Training on Accumulation of Old, Modified Proteins in Young and Older Adults

NCT01477164
View directory record Official record
Conditions
Sarcopenia
Interventions
High intensity aerobic exercise, Resistance exercise training, Combined
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Nov 1, 2026, 5:03 PM EST
Completed No phase listed Observational Accepts healthy volunteers

"Mind in Motion": Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults

NCT03737760
View directory record Official record
Conditions
Effect of Age-related Changes in the Brain on Walking Ability
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
20 Years to 110 Years
Enrollment
279 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Nov 1, 2026, 5:03 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Appetite Regulation in Older-Aged Obese Individuals

NCT02721303
View directory record Official record
Conditions
Obesity, Aging
Interventions
3-day diet Run-in, fMRI, Intravenous catheter placed for blood draws
Dietary Supplement · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Nov 1, 2026, 5:03 PM EST
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of a Proprietary Blend of Herbal Extract Supplement on Cellular Detoxification, Inflammation, and Cumulative Cognitive Index as Well as Gene Expression in Middle-Aged Adult Women

NCT01598272
View directory record Official record
Conditions
Anti Aging
Interventions
Vitality product AM + Vitality product PM, Placebo
Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
35 Years to 73 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Orem, Utah
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Nov 1, 2026, 5:03 PM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Retinol on Human Skin Aging in East Asian Descent

NCT02906566
View directory record Official record
Conditions
Intrinsic Aging of Skin
Interventions
Retinol, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Nov 1, 2026, 5:03 PM EST
Terminated Phase 4 Interventional Accepts healthy volunteers

Investigation of Macular Pigment Augmentation on Dark Adaptation

NCT00478439
View directory record Official record
Conditions
Aging, Age-Related Macular Degeneration
Interventions
ZeaVision EyePromise Restore, Multivitamin
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 27, 2010 · Synced Nov 1, 2026, 5:03 PM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Independent Walking for Brain Health

NCT03058146
View directory record Official record
Conditions
Physical Activity, Aging
Interventions
Mobile Health Walking Condition, Healthy Aging Education Condition
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Nov 1, 2026, 5:03 PM EST