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Showing 1441–1464 of 1,650 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

ACHIEVE Hearing Intervention Follow-Up Study

NCT05070429
Conditions
Hearing Loss, Aging
Interventions
Clinic-based audiological rehabilitative service delivery, Telehealth audiological rehabilitative service delivery
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years to 88 Years
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Conditions
Aging
Interventions
Whole Genome Sequencing Analysis
Genetic
Lead sponsor
Puer Research, LLC
Network
Eligibility
6 Years to 18 Years
Timeline
2025 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Skin Aging
Interventions
Investigational Facial Serum #3, Investigational Facial Serum #1, Investigational Facial Serum #2
Other
Lead sponsor
Victoria Collotta
Industry
Eligibility
35 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Needham, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Brain Health Virtual Reality Study

NCT06124339
Conditions
Aging, Aging Problems, Memory Loss, Memory Impairment, Memory Disorders in Old Age, Memory Disorder, Spatial, Memory Disorders, Mild Cognitive Impairment, Cognitive Decline, Cognitive Change, Cognition Disorders in Old Age
Interventions
Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
San Diego, California
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
20 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Iterative Design Trial to Assess Dietary Supplements and Other Aging-targeted Therapies

NCT07202403
Conditions
Aging, Longevity
Interventions
Spermidine
Dietary Supplement
Lead sponsor
Atria Research and Global Health Institute (ARGHI)
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Program for African American Cognition & Exercise

NCT03474302
Conditions
Aging
Interventions
Physical Activity, Successful Aging
Behavioral · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
65 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

NCT04018092
Conditions
Cognitive Aging, Alzheimer Disease, Protection Against
Interventions
Active NIR-PBM, Sham NIR-PBM
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Conditions
Renal Disease, End Stage, Palliative Care, Decision Aids
Interventions
Advance Care Planning Video Decision Aid
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
65 Years and older
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
Palo Alto, California • Boston, Massachusetts • Springfield, Massachusetts + 3 more
Conditions
Aging, Manual Dexterity, Piano Therapy
Interventions
Piano training (Active), Piano Training (Passive)
Behavioral
Lead sponsor
Westminster College
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Wilmington, Pennsylvania
Conditions
Sarcopenia
Interventions
Resistance Training Intervention, Active Control Group
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
65 Years to 84 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Kingston, Rhode Island
Completed Phase 2 Interventional Results available

Ghrelin Plus Strength Training in Frail Elderly Study

NCT01898611
Conditions
Frailty Syndrome
Interventions
Ghrelin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
70 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Physical Activity
Interventions
Isometric Contraction Exercise - Young Adults (Age group 18-39), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59), Isometric Contraction Exercise - Old Adults (Age group >60)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Breast Cancer, Aging
Interventions
Walk With Ease
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years to 59 Years · Female only
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Quercetin on Metabolic Health

NCT05297032
Conditions
Quercetin, Lipid Metabolism, Aging
Interventions
Quercetin Phytosome
Dietary Supplement
Lead sponsor
Thorne HealthTech, Inc
Industry
Eligibility
20 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Summerville, South Carolina
Conditions
Aging
Interventions
Just Care
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Golden, Colorado • University Park, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Acute Pain on Motor Learning in Young vs Older Adults

NCT05471557
Conditions
Aging, Pain, Acute, Cognitive Decline, Motor Activity
Interventions
pain delivery
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Terminated Phase 4 Interventional Results available

TOM: Testosterone in Older Men With Sarcopenia

NCT00240981
Conditions
Sarcopenia, Hypogonadism, Muscular Diseases
Interventions
Topical testosterone gel 1% (active formulation), Topical gel (placebo formulation)
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
65 Years and older · Male only
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Enrolling by invitation Early Phase 1 Interventional Accepts healthy volunteers

Transient Receptor Potential Channels

NCT06444594
Conditions
Aging
Interventions
TRPM8 Agonist, TRPV1 Agonist, TRPV4 Agonist, TRPM8, TRPV4, TRPV1 Agonists, Vehicle gel
Drug · Other
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Sarcopenia
Interventions
High intensity aerobic exercise, Resistance exercise training, Combined
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Autism Spectrum Disorder
Interventions
Strengthening Skills Program, PEERS Social Skills Program
Behavioral
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
21 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tempe, Arizona
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Fisetin to Improve Vascular Function in Older Adults

NCT06133634
Conditions
Aging, Endothelial Dysfunction, Arterial Stiffness
Interventions
Fisetin, Placebo
Dietary Supplement · Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
65 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Hip Fracture, Testosterone Deficiency, Muscle Weakness
Interventions
Testosterone gel
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
St Louis, Missouri
Recruiting Not applicable Interventional Accepts healthy volunteers

Fatty Acid Modulation of Brain Function in Older Adults

NCT06192407
Conditions
Aging
Interventions
High Oleic Acid Diet, High Palmitic Acid Diet
Dietary Supplement
Lead sponsor
University of Vermont
Other
Eligibility
65 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Burlington, Vermont