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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:18 PM EDT

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Showing 193–216 of 1,647 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aging Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Facial Exercise on the Appearance of Aging

NCT01689012
View directory record Official record
Conditions
Aging
Interventions
Facial Exercise
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 23, 2026, 9:18 PM EDT
Recruiting Phase 1 Interventional

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

NCT07290244
View directory record Official record
Conditions
Open Angle Glaucoma (OAG), NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Interventions
ER-100 epigenetic therapy
Genetic
Lead sponsor
Life Biosciences Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
4
States / cities
Glendale, California • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Training to Enhance Cognition in Older Adults

NCT03900702
View directory record Official record
Conditions
Cognitive Enhancement, Aging
Interventions
Gaze-driven training games
Behavioral
Lead sponsor
Jeanne Townsend, PhD
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hyaluronic Filler for Improvement of Radial Cheek Lines

NCT06074302
View directory record Official record
Conditions
Aging
Interventions
RHA Redensity
Device
Lead sponsor
Main Line Center for Laser Surgery
Other
Eligibility
31 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Results available

Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults

NCT04284553
View directory record Official record
Conditions
Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction, Adverse Drug Event
Interventions
Order Entry, Open Encounter, Follow-up booster Alert, Cold State outreach, Simplified, Sign-off alert, Pre-commitment, Different Risks, Standard Epic Basic Alert, Enhanced Alert
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Braintree, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Poly-L-lactic Acid for Skin Quality

NCT02003833
View directory record Official record
Conditions
Skin Aging
Interventions
Poly-L-lactic acid, Placebo comparator
Device
Lead sponsor
Sadick Research Group
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Carmel, Indiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2015 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Phase 2 Interventional

Improving Physical Ability and Cellular Senescence Elimination in HIV

NCT07144293
View directory record Official record
Conditions
HIV, Frailty, Prefrail, Aging Problems
Interventions
Dasatinib, Quercetin, Placebo - Dasatinib, Placebo - Quercetin
Drug · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
50 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
24
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Not yet recruiting Phase 2 Interventional

Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV

NCT07871552
View directory record Official record
Conditions
Epigenetic Aging
Interventions
Switch from an ART regimen containing lamivudine (3TC) or emtricitabine (FTC) + tenofovir alafenamide (TAF) or tenofovir disoproxil fumarate (TDF) to DOR/ISL, Switch from an nucleoside reverse transcriptase inhibitor (NRTI)-sparing ART regimen containing greater than or equal to 2 drugs to DOR/ISL, Continue SoC ART
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
35 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quantifiably Determine if the Botanical Formulation, LLP-01, Has a Significant Clinical Effect on Proteomic Inflammatory and Cardiovascular Biomarkers in Healthy, Older Individuals.

NCT06065241
View directory record Official record
Conditions
Aging, Inflammation
Interventions
LLP-01, Placebo
Dietary Supplement · Other
Lead sponsor
LL Prosper Inc.
Industry
Eligibility
50 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Cycled Testosterone Replacement Study

NCT00957528
View directory record Official record
Conditions
Hypogonadism
Interventions
Testosterone, Placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
60 Years to 85 Years · Male only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Oct 23, 2026, 9:18 PM EDT
Completed No phase listed Observational

Develop and Validate Ultrasonic Device for Osteoporotic Fracture Risk Assessment

NCT01123421
View directory record Official record
Conditions
Osteoporosis, Fracture, Aging
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 23, 2026, 9:18 PM EDT
Completed No phase listed Observational

Study of Bone Disease in Older HIV-infected Adults

NCT00935935
View directory record Official record
Conditions
Osteopenia, Osteoporosis, HIV Infection, Aging, HIV Infections
Interventions
Not listed
Lead sponsor
Ruth M. Rothstein CORE Center
Other
Eligibility
50 Years to 70 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2012 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smart Television and Exercise Promotion for Independent Living Facilities

NCT03001778
View directory record Official record
Conditions
Aging, Physical Activity
Interventions
Usability Testing
Other
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
55 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health

NCT02453178
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Cycling
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans

NCT00099697
View directory record Official record
Conditions
Aging, Obesity, Insulin Resistance
Interventions
DHEA
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years to 78 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Oct 23, 2026, 9:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Human Skin Aging: Clinical Parameters and Gene Expression Profiling

NCT01451476
View directory record Official record
Conditions
Ageing
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 23, 2026, 9:18 PM EDT
Enrolling by invitation Phase 4 Interventional

Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women

NCT07057310
View directory record Official record
Conditions
Obesity, Menopause
Interventions
semaglutide or tirzepatide, Lifestyle modification intervention
Drug · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
46 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional

The Effects of a High Protein Diet on Microbiota, Gastrointestinal Function and Wellness in Older Women

NCT02445560
View directory record Official record
Conditions
Aging
Interventions
Probiotic capsule and Fiber Sachet, Probiotic capsule and Placebo sachet, Placebo capsule and Fiber Sachet, Placebo capsule and Placebo sachet
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
2
States / cities
Gainesville, Florida • Ocala, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 23, 2026, 9:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted: A Trial of Acute Effects on Biomarkers of Healthy Aging

NCT03511352
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Stand More
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Phase 1Phase 2 Interventional

Lomecel-B on Vaccine-Specific Antibody- Response in Subjects With Aging Frailty

NCT02982915
View directory record Official record
Conditions
Aging Frailty
Interventions
Longeveron Mesenchymal Stem Cells (LMSCs), Fluzone High Dose Vaccine
Biological
Lead sponsor
Longeveron Inc.
Industry
Eligibility
65 Years to 90 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
6
States / cities
Coral Gables, Florida • Fort Myers, Florida • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2022 · Synced Oct 23, 2026, 9:18 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

NCT06367738
View directory record Official record
Conditions
Aging
Interventions
Psilocybin
Drug
Lead sponsor
University of California, Berkeley
Other
Eligibility
60 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 23, 2026, 9:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Hazelnut Consumption in Improving Micronutrient Status in Older Adults

NCT03485989
View directory record Official record
Conditions
Nutrition Poor, Micronutrient Deficiency, Aging
Interventions
Hazelnuts
Other
Lead sponsor
Oregon State University
Other
Eligibility
55 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 23, 2026, 9:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Carbon Dioxide Administration and Brain Waste Clearance

NCT07357090
View directory record Official record
Conditions
Traumatic Brain Injury, Aging Disorder, Magnetic Resonance Imaging (MRI)
Interventions
Hypercapnia task performed during fMRI
Other
Lead sponsor
Andrew Mayer
Other
Eligibility
18 Years to 82 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 23, 2026, 9:18 PM EDT
Not listed No phase listed Observational

Platelet Immune Responses in Aging and Influenza and Sepsis (INVACS)

NCT03010410
View directory record Official record
Conditions
Sepsis, Influenza
Interventions
Not listed
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 23, 2026, 9:18 PM EDT