- Conditions
- Age Related Cognitive Decline, Alzheimer's Disease, Vascular Dementia, Endothelial Dysfunction, Executive Dysfunction
- Interventions
- Omega 3 PUFA, Placebo
- Drug
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 75 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2021
- U.S. locations
- 1
- States / cities
- Portland, Oregon
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Showing 1–24
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- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 70 Years and older
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
- Interventions
- Not listed
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 289 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2021
- U.S. locations
- 19
- States / cities
- Sun City, Arizona • Irvine, California • La Jolla, California + 14 more
- Conditions
- Cognitive Decline
- Interventions
- ProdromeNeuro Omega 3 Oil Nutritional Supplement
- Dietary Supplement
- Lead sponsor
- Neurological Associates of West Los Angeles
- Other
- Eligibility
- 35 Years to 65 Years · Male only
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Santa Monica, California
- Conditions
- Traumatic Brain Injury, Aging Related Cognitive Decline
- Interventions
- Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
- Combination Product
- Lead sponsor
- Minneapolis Veterans Affairs Medical Center
- Federal
- Eligibility
- 65 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease, Huntington Disease, Lewy Body Disease, Creutzfeldt-Jakob Syndrome, Frontotemporal Lobar Degeneration, Cognitive Dysfunction, Cognitive Aging, Chronic Disease, Palliative Care, Patient Care, Health Care Quality, Access, and Evaluation, Patient Care, Health Communication, Patient Care Planning, Quality of Life
- Interventions
- Jumpstart Guide
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,802 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 3
- States / cities
- Seattle, Washington
- Conditions
- Age-related Cognitive Decline
- Interventions
- MRI
- Device
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 45 Years to 100 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2011
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Aging, Alzheimer Disease, Age-related Cognitive Decline
- Interventions
- Brain training, Paced breathing
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 50 Years to 70 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Cognition Disorders, Brain Pathology, Physical Disability, Physical Activity, Aging
- Interventions
- Aerobic Activity, Resistance Training, Yoga, Health Education
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 65 Years to 80 Years
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Age-related Cognitive Decline
- Interventions
- Multi-tasking Training
- Behavioral
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 60 Years to 75 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Mild Cognitive Impairment, Prediabetes
- Interventions
- Exercise/Aerobic, Exercise/Stretching
- Behavioral
- Lead sponsor
- Wake Forest University
- Other
- Eligibility
- 50 Years to 89 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy, Cardiovascular Diseases, Neoplasms, Cognitive Dysfunction, Metabolic Syndrome, Frailty, Musculoskeletal Disease, Neurodegenerative Disease, Dementia, Activities of Daily Living, Health Related Quality of Life, Disability Physical, Environmental Exposure, Occupational Diseases, Health Equity, Social Determinants of Health
- Interventions
- Multi-Domain Ecological and Clinical Data Linkage
- Other
- Lead sponsor
- Longevity Metrics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2099
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Aging, Cognitive Impairment, Physical Activity
- Interventions
- Gerofit exercise, Health education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 65 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- West Los Angeles, California • Baltimore, Maryland
- Conditions
- Cognitive Deterioration, Disorder of Aging
- Interventions
- aerobic training, Wait list
- Behavioral
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 20 Years to 75 Years
- Enrollment
- 233 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, Functional Status, PreDiabetes, Aging, Depression
- Interventions
- Continuous Glucose Monitoring System (CGMS)
- Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Mild Cognitive Impairment
- Interventions
- Cannabidiol, Placebo
- Drug · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 236 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
- Interventions
- Comprehensive Multi-System Clinical Screening
- Diagnostic Test
- Lead sponsor
- Longevity Metrics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2099
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Interventions
- MBCT+w, ALED
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services, Patient Participation, Health Behavior, Aging, Cardiovascular Diseases, Metabolic Syndrome, Cognitive Dysfunction, Frailty, Activities of Daily Living, Health Related Quality of Life, Health Equity, Telemedecine
- Interventions
- Interactive Personalized Health Report, Mobile Community-Based Health Screenings, Hybrid Medical Droid and Human Delivered Health Screenings
- Behavioral
- Lead sponsor
- William Brandenburg, MD
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2099
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Aging
- Interventions
- Tai Chi, Guided autobiography, Qigong, Successful aging, Combination, Comparison
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 70 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Hearing Loss, Depression
- Interventions
- Phonak Audeo B-R 90 hearing aid device (Active), Duloxetine or escitalopram, Audeo B-R 90 hearing aid device (Sham)
- Device · Drug
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 60 Years to 99 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Age Related Cognitive Decline, Age Related Macular Degeneration
- Interventions
- Walnuts, habitual diet
- Dietary Supplement · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 63 Years to 79 Years
- Enrollment
- 708 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Interventions
- Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham
- Other
- Lead sponsor
- Hebrew SeniorLife
- Other
- Eligibility
- 65 Years to 90 Years
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Roslindale, Massachusetts