Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 72 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Air Pollution: Strategies for Personalized Intervention to Reduce Exposure

NCT03744871
Conditions
Air Pollution
Interventions
N95 Respirator
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Coronary Heart Disease, Cardiovascular Diseases, Environmental Exposure
Interventions
AIRWISE
Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Missoula, Montana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Biological Responses to Low Level Ozone

NCT02857283
Conditions
Environmental Exposure, Nasal Inflammation
Interventions
Ozone, Filtered Air, Health and Exposure Tracker (HET)
Other · Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Ozone Cardiovascular Effects in Genetically Susceptible People

NCT01192477
Conditions
Healthy
Interventions
Ozone
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Traffic Pollution Exposure Improves Blood Pressure

NCT04029129
Conditions
Air Pollution
Interventions
Air filtration and building envelop modifications
Other
Lead sponsor
UConn Health
Other
Eligibility
40 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Farmington, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Particulate Matter, Blood Pressure, and the Sympathetic Nervous System

NCT03079843
Conditions
Air Pollution
Interventions
exposure to particulate matter with N 95 facemask, exposure to particulate matter with no face mask
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Air Pollution, Atherosclerosis
Interventions
HEPA filtration, Sham filtration
Device
Lead sponsor
University of Southern California
Other
Eligibility
65 Years to 84 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Completed No phase listed Observational Accepts healthy volunteers

Lung Mucus Hypersecretion and NQO1

NCT00729352
Conditions
Environmental Exposure, Ozone, Air Pollution, Genetic Susceptibility
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Cardiovascular Diseases, Blood Pressure, Glycated Hemoglobin (HbA1c), Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Indoor Air Quality, Particulate Matter, Health Behavior
Interventions
Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control
Behavioral · Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years to 79 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Missoula, Montana
Conditions
Asthma, Pollution; Exposure
Interventions
Residential mechanical ventilation system (Exhaust), Residential mechanical ventilation system (CFIS) and air filtration upgrades, Residential mechanical ventilation system (ERV) and air filtration upgrades
Device
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Environmental Exposure
Interventions
Informational Report
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
15 Years to 99 Years
Enrollment
105 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study

NCT07151235
Conditions
Healthy Participants
Interventions
Simulated wildfire smoke exposure, Clean Air exposure
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Not listed No phase listed Observational Accepts healthy volunteers

El Sendero: Pathways to Health Study

NCT05551650
Conditions
Obesity, Childhood, Child Development
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 6 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

AIM to Improve Asthma: Airflow Improvements During Meal-Prep

NCT04464720
Conditions
Asthma in Children, Pollution; Exposure
Interventions
Cooking Ventilation Intervention
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
6 Years to 12 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Berkeley, California
Conditions
Asthma
Interventions
High Efficiency Particulate Air Cleaner, Sham air cleaner
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland
Conditions
Healthy
Interventions
Fish oil, Olive oil
Dietary Supplement
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
50 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
PreDiabetes
Interventions
PAC with HEPA filter intact, PAC with HEPA filter removed
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Juice Types on the Responses to Air Pollution

NCT02027415
Conditions
Air Pollution
Interventions
Beet juice, Orange juice
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Piscataway, New Jersey
Not listed No phase listed Observational Accepts healthy volunteers

Cardiovascular Effects of Exposure to Ozone

NCT01487005
Conditions
Cardiovascular Injury
Interventions
Not listed
Lead sponsor
Health Effects Institute
Other
Eligibility
55 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
4
States / cities
San Francisco, California • Watertown, Massachusetts • Rochester, New York + 1 more
Conditions
Air Pollution Exposure, Oxidative Stress, Airway Inflammation
Interventions
Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
Other
Lead sponsor
Georgia Southern University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Savannah, Georgia
Conditions
Asthma
Interventions
Active Air Purifier, Placebo Air Purifier
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Pollutant Altered Allergic Responses

NCT00011440
Conditions
Allergic Rhinitis, Allergy
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2002
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Asthma
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Raleigh, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Interaction Effects of Temperature and Ozone

NCT01981135
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean Air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina