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ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:31 AM EDT

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Showing 241–264 of 1,105 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol & Drug Use Clear all
Completed Early Phase 1 Interventional Results available

mHealth to Help Pregnant and Postpartum Women in Recovery for Opioid Use Disorder

NCT06701123
View directory record Official record
Conditions
Opioid Use Disorders
Interventions
uMAT-R mobile app with coaching component
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Early Phase 1 Interventional Results available

Managing Chronic Pain in Veterans With Substance Use Disorders

NCT00982410
View directory record Official record
Conditions
Chronic Pain
Interventions
cognitive-behavioral treatment, educational supportive group
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 13, 2015 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

NCT03855410
View directory record Official record
Conditions
Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use, Sexual Risk Behavior
Interventions
S4E, Attention-Matched Control Group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 24, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth

NCT06929520
View directory record Official record
Conditions
E-cigarette Use, Substance Use
Interventions
ENDS Prevention Intervention (TBD)
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
10 Years to 14 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Centralized Virtual SBIRT for Pediatric Primary Care

NCT06486688
View directory record Official record
Conditions
Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions
Centralized Virtual SBIRT
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 17 Years
Enrollment
22,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Phase 2 Interventional

Recovery Management Checkups for Women Offenders

NCT01334164
View directory record Official record
Conditions
Recovery Management Checkup (RMC), Outcome Monitoring
Interventions
Recovery Management Checkups, Outcome Monitoring
Behavioral · Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older · Female only
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
2
States / cities
Chicago, Illinois • Normal, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2015 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

NCT04927143
View directory record Official record
Conditions
Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use, Substance Use, Methamphetamine Abuse, Methamphetamine-dependence
Interventions
App-Based Contingency Management, Sham Control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Oconomowoc, Wisconsin • Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Brief Behavioral Therapy for Insomnia (BBTI) in SUD Recovery

NCT05935735
View directory record Official record
Conditions
Substance Use Disorders, Insomnia
Interventions
Brief Behavioral Therapy for Insomnia (BBTI)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

E-health Implementation (Iowa)

NCT03954184
View directory record Official record
Conditions
Substance Use Disorders
Interventions
NIATx-TI with Product Training/On-line Support
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
23,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
49
States / cities
Adel, Iowa • Algona, Iowa • Ames, Iowa + 44 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Phase 2 Interventional Results available

Mindfulness Meditation for Health

NCT01056484
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 6, 2014 · Synced Oct 24, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Veterans With SUD and PTSD

NCT05327504
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy, Neutral Topic Writing
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional

Differential Sensitivity Markers in Youth Drug Abuse Prevention

NCT02622451
View directory record Official record
Conditions
Adolescent Substance Use
Interventions
Teen Intervene, Everyday Parenting
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 24, 2026, 5:31 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Peer MI for Substance-using Emerging Adults

NCT03264872
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Peer-Enhanced Motivational Interviewing, Waitlist Control
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 29 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Phase 2 Interventional

Home Based Treatment for Drug Use in Early Adolescents

NCT00280228
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
Interventions
Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
11 Years to 14 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2011 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

NCT04561544
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Substance Use
Interventions
Knowing Who You Are (Becoming): Cultural Identity Intervention
Behavioral
Lead sponsor
University of Alaska Anchorage
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Oct 24, 2026, 5:31 AM EDT
Withdrawn Not applicable Interventional

Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders

NCT03652311
View directory record Official record
Conditions
Substance Use Disorders
Interventions
ThermoNeuroModulation TNM Device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Oct 24, 2026, 5:31 AM EDT
Terminated Phase 3 Interventional Results available

Intervention for Teens With ADHD and Substance Use

NCT02502799
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate
Behavioral · Drug
Lead sponsor
Florida International University
Other
Eligibility
12 Years to 16 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Brief Intervention in At-Risk First-time Mothers

NCT00230009
View directory record Official record
Conditions
Substance Use
Interventions
Brief motivational intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced Oct 24, 2026, 5:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Network Study: Soldiers Connecting for Work and Health

NCT04463225
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet-Delivered Brief Intervention
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

The Rewire Study (Mindfulness Mobile App to Reduce Adolescent Substance Use)

NCT03533491
View directory record Official record
Conditions
Adolescent Substance Use
Interventions
Rewire App
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
13 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Oct 24, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

The Hastiin Bidziil (Strong Man) Intervention

NCT06559774
View directory record Official record
Conditions
Substance Use
Interventions
Hastiin Bidziil, Control condition - vehicle maintenance
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older · Male only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Chinle, Arizona • Fort Defiance, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing

NCT05479890
View directory record Official record
Conditions
Motivational Interviewing, Alcohol Use Disorder
Interventions
ClientBot
Other
Lead sponsor
Lyssn.io, Inc.
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 24, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Testing and Evaluation of the Returning to the Land Intervention to Address and Prevent Substance Misuse

NCT07695818
View directory record Official record
Conditions
Substance Use, Children, Cultural Factors
Interventions
Returning to the Land - Biodiverse Outdoor Setting, Control
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years to 19 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Box Elder, Montana
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 24, 2026, 5:31 AM EDT
Completed Not applicable Interventional

Recovery Management Checkups for Primary Care Experiment

NCT03746756
View directory record Official record
Conditions
Substance Use Disorders
Interventions
SBIRT, SBIRT+RMC-PC
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
4
States / cities
Chicago, Illinois • Lansing, Illinois • Oak Park, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Oct 24, 2026, 5:31 AM EDT