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ClinicalTrials.gov public records Last synced Oct 24, 2026, 6:15 AM EDT

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Showing 265–288 of 1,105 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol & Drug Use Clear all
Completed Not applicable Interventional

Effects of Breathwork and Meditation on Addiction Recovery

NCT07510256
View directory record Official record
Conditions
Addiction, Addiction Disorders
Interventions
SKY Breathing Program
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sanborn, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nen ŨnkUmbi/EdaHiYedo Plus (We Are Here Now Plus): a Multi-level Intervention to Reduce Health Disparities Among American Indian Youth

NCT07460973
View directory record Official record
Conditions
Healthy, Condom Use, Mental Health, Substance Use (Drugs, Alcohol)
Interventions
NE+, Control
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
12 Years to 18 Years
Enrollment
843 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults

NCT02667119
View directory record Official record
Conditions
Substance Use Disorder, Posttraumatic Stress Disorder
Interventions
Prolonged Exposure with Contingency Management, Standard Care
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 25 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
3
States / cities
Farmington, Connecticut • Hartford, Connecticut • New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Usability Testing for the Reward-based Technology to Improve OUD Treatment

NCT05159362
View directory record Official record
Conditions
Opioid-use Disorder, Contingency Management, Medication for Opioid-use Disorder
Interventions
Software Application
Other
Lead sponsor
Q2i, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Phase 4 Interventional

Buprenorphine and Integrated HIV Care

NCT00317460
View directory record Official record
Conditions
Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS, HIV Infections
Interventions
Physician Management, Counseling
Other · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

HIV+ Substance Users Released From Jail

NCT03834779
View directory record Official record
Conditions
HIV/AIDS, Substance Use Disorders
Interventions
DOORS-CHW Intervention
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction

NCT07344233
View directory record Official record
Conditions
Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
Interventions
Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

California MEPS Hub

NCT07433985
View directory record Official record
Conditions
HIV Prevention, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP), Incarceration, Hepatitis C Virus (HCV), Substance Use Disorder (SUD)
Interventions
Mobile Enhanced Prevention Support (MEPS), Control
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 59 Years · Male only
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
Oakland, California • Riverside, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional

rTMS as Add on Treatment for Substance Use Disorders

NCT06963476
View directory record Official record
Conditions
Opioid Use, Alcohol Use Disorder
Interventions
repetitive transcranial magnetic stimulation (rTMS) for AUD, repetitive transcranial magnetic stimulation (rTMS) for OUD
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional

International Latino Research Partnership

NCT02038855
View directory record Official record
Conditions
Substance Use (Drugs, Alcohol)
Interventions
Integrated Intervention for Dual Problems and Early Action
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Exercise as a Treatment for Substance Use Disorders Protocol

NCT01141608
View directory record Official record
Conditions
Stimulant Abuse and Dependence
Interventions
Vigorous Intensity High Dose Exercise, Health Education Intervention
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
9
States / cities
Denver, Colorado • Jacksonville, Florida • Cape Girardeau, Missouri + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia

NCT05471921
View directory record Official record
Conditions
Alcohol and Substance-Related Mental Disorders
Interventions
SBIRT, Treatment as usual
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reinforcing Therapist Performance

NCT01016704
View directory record Official record
Conditions
Substance Use
Interventions
Incentive
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Normal, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2011 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Trial of the Positive Action Program in Chicago Schools and Extension to Grade 8

NCT01025674
View directory record Official record
Conditions
Character, Violence, Substance Use, Pro-Social Behavior, Academic Achievement
Interventions
Positive Action program
Behavioral
Lead sponsor
Oregon State University
Other
Eligibility
6 Years and older
Enrollment
4,230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
2
States / cities
Chicago, Illinois • Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 22, 2015 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing Youth

NCT01829789
View directory record Official record
Conditions
Substance Use Disorders, Treatment Refusal
Interventions
Group Community Reinforcement Training for Parents, Individual Community Reinforcement Training for Parents
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Telehealth-Clinical Advocacy Project

NCT04911426
View directory record Official record
Conditions
Substance Use
Interventions
Telehealth
Behavioral
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Waukegan, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

NCT04134767
View directory record Official record
Conditions
Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis), Overdose, Drug, Opioid Use
Interventions
Health Linkage, Overdose Education
Behavioral
Lead sponsor
April M Young
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Project Matter: Intervention to Improve HIV Self-care Among Men Who Have Sex With Men (MSM) With Substance Use Disorders

NCT03899220
View directory record Official record
Conditions
Substance Use Disorders, HIV/AIDS, Homosexuality, Male
Interventions
Project Matter
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Adolescents From Entering the Juvenile Justice System

NCT02147743
View directory record Official record
Conditions
Substance Use, Delinquency
Interventions
CCP+MDFT, CCP+SAU
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2014 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

NCT04163341
View directory record Official record
Conditions
HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder, Substance Use Disorders
Interventions
Adapted Common Elements Treatment Approach
Behavioral
Lead sponsor
Michael J Mugavero, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 24, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resonance Breathing Intervention Opioid Use Disorder

NCT05830773
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Resonance Breathing Exercises
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 24, 2026, 6:15 AM EDT
Recruiting Phase 3 Interventional

Emergency Department-Initiated Medications for Alcohol Use Disorder

NCT05827159
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview, Gabapentin Pill
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

NCT03135886
View directory record Official record
Conditions
HIV/AIDS, Hepatitis C, Substance Use Disorders, Opioid-use Disorder
Interventions
Information Control, HIV and HCV Testing Practice Coaching Intervention, HIV Testing Practice Coaching Intervention
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 24, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Justice Community Overdose Innovation Network II TCU Hub

NCT07528846
View directory record Official record
Conditions
Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
Interventions
Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
1,620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 24, 2026, 6:15 AM EDT