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ClinicalTrials.gov public records Last synced Oct 31, 2026, 5:23 PM EDT

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Showing 913–936 of 1,105 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol & Drug Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Yoga Intervention for Substance Use and ART Adherence in Community Reentry

NCT02492893
View directory record Official record
Conditions
Substance Related Disorders, HIV
Interventions
Hatha yoga
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 31, 2026, 5:23 PM EDT
Withdrawn Not applicable Interventional

Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders

NCT03652311
View directory record Official record
Conditions
Substance Use Disorders
Interventions
ThermoNeuroModulation TNM Device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Leadership and Organizational Change for Implementation (LOCI) Intervention

NCT03042832
View directory record Official record
Conditions
Substance Use Disorder, Mental Health Disorder
Interventions
LOCI, Internet Based Webinar Leadership Training
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

NCARE, Transition to Recovery

NCT03737864
View directory record Official record
Conditions
Alcohol Withdrawal, Substance Use Disorders
Interventions
Patient navigation, Motivational interviewing (MI)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Fairbanks, Alaska
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Automated Recovery Line for Medication Assisted Treatment

NCT02124980
View directory record Official record
Conditions
Drug Dependence, Substance Use Disorders
Interventions
Recovery Line
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 31, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Primary Connections for Youth and Families

NCT05964010
View directory record Official record
Conditions
Substance Use
Interventions
Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 17 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 2 Interventional Results available

A Novel Human Lab Model for Screening AUD Medications

NCT04249882
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Placebo, Naltrexone, Varenicline
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

CBT4CBT for Women in Residential Treatment for Substance Use Disorders

NCT03678051
View directory record Official record
Conditions
Substance Use Disorders, Drug Abuse, Drug Addiction, Substance Abuse, Drug Use Disorders, Drug Dependence, Substance Addiction
Interventions
Treatment as Usual (TAU), TAU+CBT4CBT
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

NCT04546061
View directory record Official record
Conditions
Substance Use, Mental Health
Interventions
Project Uplift
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Brief New Treatment for Suicide Attempts

NCT03300596
View directory record Official record
Conditions
Suicide, Attempted, Drug Use, Alcohol; Use, Problem
Interventions
Brief intervention to prevent suicide attempt, Enhanced treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Oct 31, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Personalized Approach to Healthy Use and Recovery (PATH) Trial

NCT06580457
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Personal Causal Model + Personalized Feedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction

NCT02378181
View directory record Official record
Conditions
Alcohol Use, Drug Use
Interventions
Health Education Toolkit, Treatment-as-usual
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 4 Interventional Results available

Creatine as a Treatment Option for Depression in Methamphetamine Using Females

NCT01514630
View directory record Official record
Conditions
Depression, Substance Abuse, Substance Use, Neuroimaging, Dual Diagnosis
Interventions
Creatine monohydrate
Drug
Lead sponsor
Perry Renshaw
Other
Eligibility
13 Years to 64 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Oct 31, 2026, 5:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Weaving Healthy Families Program

NCT03924167
View directory record Official record
Conditions
Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse, Diet Modification, Health Behavior, Health Knowledge, Attitudes, Practice, Relationship, Family, Relation, Parent-Child, Emotional Stress
Interventions
Weaving Healthy Families Program
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
5 Years to 120 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder

NCT04063267
View directory record Official record
Conditions
Cigarette Smoking, Addiction, E Cig Use
Interventions
E cigarettes, Nicotine Replacement Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 2 Interventional

Recovery Management Checkups for Women Offenders

NCT01334164
View directory record Official record
Conditions
Recovery Management Checkup (RMC), Outcome Monitoring
Interventions
Recovery Management Checkups, Outcome Monitoring
Behavioral · Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older · Female only
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
2
States / cities
Chicago, Illinois • Normal, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2015 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Statewide System and Organizational Strategy for EBP Implementation

NCT05344534
View directory record Official record
Conditions
Control, Experimental
Interventions
Leadership and Organizational Change for Implementation
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
479 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 3 Interventional Results available

Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)

NCT00264797
View directory record Official record
Conditions
ADHD, Substance Abuse
Interventions
Methylphenidate (OROS-MPH), Methylphenidate (OROS-MPH) - Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
13 Years to 18 Years
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Denver, Colorado • Jacksonville, Florida • St. Petersburg, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2013 · Synced Oct 31, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) for Treatment of Substance Use Disorder

NCT07318480
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence, Substance Use Disorder (SUD), Opioid Use Disorder, Opioid Dependence
Interventions
Transcranial Direct Current Stimulator (tDCS), Cognitive Reappraisal Training
Device · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 31, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

NCT06103370
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders, Addiction, Opioid Use, Drug Use, Intravenous Drug Usage
Interventions
Peer-educator-based network
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Frederick, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Addressing Young Men's Substance Use and HIV Risk

NCT00325702
View directory record Official record
Conditions
HIV
Interventions
community-level intervention for young MSM
Behavioral
Lead sponsor
Public Health Management Corporation
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2018 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Phase 1 Interventional Results available

W-SUDs for COVID-19

NCT04460027
View directory record Official record
Conditions
Substance Use Disorders, Alcohol Use Disorder
Interventions
Woebot Substance Use Disorder
Other
Lead sponsor
Woebot Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Substance Use and Fitness

NCT01305902
View directory record Official record
Conditions
Substance Abuse, Exercise
Interventions
contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
55 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 31, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders

NCT01104805
View directory record Official record
Conditions
Substance Abuse
Interventions
Therapeutic Education System (TES), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
10
States / cities
Danbury, Connecticut • Orlando, Florida • Waipahu, Hawaii + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 31, 2026, 5:23 PM EDT