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ClinicalTrials.gov public records Last synced Oct 31, 2026, 7:05 PM EDT

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Showing 937–960 of 1,105 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol & Drug Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students

NCT03925220
View directory record Official record
Conditions
Substance-Related Disorders, Underage Drinking, Drug Use
Interventions
The SUPPER Project, Improving nutrition and physical activity among youth
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
9 Years to 14 Years
Enrollment
402 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 31, 2026, 7:05 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

NCT06552741
View directory record Official record
Conditions
Substance Use Disorder, Alcohol Use Disorder
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2047
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD

NCT00680966
View directory record Official record
Conditions
Adolescent, Depression, Substance Use Disorders
Interventions
Adolescent Coping With Depression/Functional Family Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 12, 2014 · Synced Oct 31, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model

NCT07094061
View directory record Official record
Conditions
Substance Use, Healthy
Interventions
fMRI, Questionnaires and surveys, Behavioral tasks and eye tracking
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 22 Years
Enrollment
294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Records for Alcohol Care Enhancement

NCT05492942
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 31, 2026, 7:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Randomized Trial of a Social Networks Intervention

NCT03059433
View directory record Official record
Conditions
Adolescent Behavior
Interventions
AVID Intervention
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 18 Years
Enrollment
446 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Specialty Mental Health Probation in North Carolina

NCT02990026
View directory record Official record
Conditions
Mental Illness, Substance Use, Criminal Behavior
Interventions
Specialty Mental Health Probation
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 64 Years
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 31, 2026, 7:05 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk

NCT05828849
View directory record Official record
Conditions
Cardiovascular Disease, Alcohol Use Disorder, HIV Risk, Substance Use Disorders
Interventions
Navigation, compensation, and personalization
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Years to 64 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Phase 2 Interventional Results available

Varenicline Treatment for Cannabis Use Disorder

NCT02892110
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Substance Use Treatment and Recovery Team

NCT05086796
View directory record Official record
Conditions
Opioid-use Disorder, Opioid-Related Disorders
Interventions
Substance Use Treatment and Recovery Team (START)
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Los Angeles, California • Springfield, Massachusetts • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use

NCT05325788
View directory record Official record
Conditions
Alcohol Use Disorder, Opioid Use Disorder
Interventions
e-Covery, Comparator Condition
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 31, 2026, 7:05 PM EDT
Completed No phase listed Observational

Managerial Database II

NCT01009827
View directory record Official record
Conditions
HIV
Interventions
Observation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 24 Years
Enrollment
1,712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
14
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 31, 2026, 7:05 PM EDT
Not listed Phase 2 Interventional

Alcohol Use and Relationships - III

NCT01753986
View directory record Official record
Conditions
Intimate Partner Violence, Substance Use
Interventions
Brief Alcohol Intervention plus Standard Batterer Intervention, General Health Improvement Intervention plus Standard Batterer Intervention
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Stimulation

NCT01271413
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Computerized cognitively stimulating activities
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Enhancing Permanency in Children and Families

NCT04700696
View directory record Official record
Conditions
Substance Abuse, Substance Use, Child Abuse, Neglect, Child
Interventions
Peer Recovery Support, Family Treatment Drug Court with Medications for Opioid Use Disorders (MOUD), Relational Skill Building based on the Nurturing Parenting Program (NPP)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
Not listed
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peers Plus Mobile App for Treatment in HIV

NCT05427318
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
PATH
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Ysidro, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 31, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional

reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)

NCT05958017
View directory record Official record
Conditions
Stimulant Use Disorder, People Living With HIV
Interventions
reSET, Standard of care
Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years · Male only
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 31, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adverse Adolescent Pathways to Substance Use

NCT06977178
View directory record Official record
Conditions
Anxiety, Adolescent Development, Substance Use
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 14 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 31, 2026, 7:05 PM EDT
Terminated Not applicable Interventional

Attention Training on Smartphones

NCT04097340
View directory record Official record
Conditions
Attention, Substance Use
Interventions
Attentional Bias Retraining (ABR), Control Training
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 31, 2026, 7:05 PM EDT
Terminated No phase listed Observational

Promoting Medications for Alcohol Use Disorder on the General Medicine Service

NCT04287790
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
audit and feedback, educational meetings, and academic detailing to promote medication receipt, Acamprosate, naltrexone, or disulfiram
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 31, 2026, 7:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing a Drug Abuse Prevention Program for Dissemination

NCT03125291
View directory record Official record
Conditions
Substance Abuse, Mental Health, Educational Problems
Interventions
Bridges 4-week Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 15 Years
Enrollment
664 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Phase 1 Interventional

Medication-Assisted Treatment for Youth With Substance Use Disorders

NCT02593474
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Dependence
Interventions
Naltrexone
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
16 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SARA - Substance Abuse Research Assistant

NCT03255317
View directory record Official record
Conditions
Substance Use
Interventions
Reinforcers, Notifications
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 24 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Oct 31, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Feasibility of SBIRT-PN

NCT03057119
View directory record Official record
Conditions
Substance Use, HIV/AIDS, Older Adults, Behavioral Intervention, Infectious Disease
Interventions
Psycho-educational content (5 Minutes), Readiness Assessment (10 minutes), Goal-Setting (5 minutes), Identifying and prioritizing needs (5 minutes), Explanation of Peer Navigator and Session wrap (5 minutes)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 85 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida • Lake City, Florida
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 31, 2026, 7:05 PM EDT