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Showing 1–24 of 281 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Abuse, Alcohol Dependence Clear all
Withdrawn No phase listed Observational

Brain-imaging and Adolescent Neuroscience Consortium

NCT01511679
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Sep 24, 2026, 9:32 AM EDT
Recruiting Phase 2 Interventional

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Interventions
Psilocybin, Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text-based Alcohol Prevention for First Year College Students

NCT03864237
View directory record Official record
Conditions
College Drinking
Interventions
Alcohol texts, Attention control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 20 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 24, 2026, 9:32 AM EDT
Terminated Phase 2 Interventional Results available

Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD

NCT03852628
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Abuse
Interventions
2mg Buprenex and 380mg Vivitrol, Placebo (SL pill qd, IM injection q4weeks)
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Tuscaloosa, Alabama • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 2 Interventional

The iHealth Study in College Students

NCT00183131
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts, Hazardous Alcohol Use
Interventions
Brief Personalized Feedback
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2010 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

NCT00802321
View directory record Official record
Conditions
Alcohol Related Disorders, Alcoholism, Alcohol Abuse
Interventions
Dutasteride
Drug
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 55 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2010 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Results available

An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence

NCT00667875
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Placebo, Naltrexone, Naltrexone + Aripiprazole
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personal Values and Mandated Students

NCT03247647
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Enhanced Intervention, Standard Intervention
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 24 Years
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
2
States / cities
Binghamton, New York • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 24, 2026, 9:32 AM EDT
Not yet recruiting Not applicable Interventional

Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior

NCT07769580
View directory record Official record
Conditions
HIV, Risk Behavior, Alcohol Abuse
Interventions
CLT- Concrete text messages, CLT- Abstract text messages, Control messages, No messages, GamePlan Online Program
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 24, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

Evaluating a One-Year Version of the Parent-Child Assistance Program

NCT06163651
View directory record Official record
Conditions
Alcohol Use Disorder, Substance Use Disorders, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use Disorders, Drug Use Complicating Pregnancy, Unspecified Trimester
Interventions
Parent-Child Assistance Program - One-Year Version
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Enid, Oklahoma • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Mobile Text Messaging to Reduce Problem Drinking

NCT01885312
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention, Assessment only
Behavioral · Other
Lead sponsor
Northwell Health
Other
Eligibility
21 Years to 65 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Results available

Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment

NCT00288886
View directory record Official record
Conditions
Substance Use Disorders, Alcohol Abuse, Alcoholism, Substance Dependence, Substance Abuse
Interventions
Contracting, Prompting and Reinforcement arm, Control arm
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Jackson, Mississippi • Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Results available

Mifepristone Treatment of Alcohol Use Disorder

NCT02179749
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorders, Alcohol Abuse, Alcoholism
Interventions
Mifepristone 1200 mg daily, Standardized behavioral therapy, Placebo
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women

NCT00127231
View directory record Official record
Conditions
HIV Infections, Alcoholism
Interventions
Brief alcohol intervention based on Project Treat, Standard care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional

Phased Treatment for Social Anxiety Disorder and Coping Behaviors in a Medical Setting

NCT00862212
View directory record Official record
Conditions
Social Anxiety Disorder, Alcohol Use Disorders
Interventions
Brief Alcohol Intervention
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Minneapolis, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2013 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 4 Interventional Results available

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

NCT00595556
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
zonisamide, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2010 · Synced Sep 24, 2026, 9:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

An Evaluation of Innerview™, a Web-based Tool to Support the Integration of Mental Health in the Primary Care Setting

NCT02025647
View directory record Official record
Conditions
Mental Health
Interventions
Not listed
Lead sponsor
Pearson/Clinical Assessment
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
5
States / cities
Roseville, California • Denver, Colorado • Rockford, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2015 · Synced Sep 24, 2026, 9:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

90-Day Online Substance Use Program

NCT03069118
View directory record Official record
Conditions
Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
Interventions
Treatment - Workit Health Online Program, Control - Resource List
Behavioral
Lead sponsor
Workit Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 4 Interventional Results available

Dutasteride Treatment for the Reduction of Heavy Drinking in Men

NCT01758523
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
Dutasteride, sugar pill
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional

Improving Health Behaviors Through Telephone Linked Care

NCT00314197
View directory record Official record
Conditions
Diet, Physical Activity, Smoking, Alcohol Abuse
Interventions
Telephone Linked Care - Behavior Change Counseling System, Telephone-linked behavioral counseling
Behavioral
Lead sponsor
American Academy of Family Physicians
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Leawood, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2007 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse

NCT00220597
View directory record Official record
Conditions
Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior, Sexually Transmitted Diseases, Viral
Interventions
Trauma-focused group therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2013 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Results available

Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence

NCT02210195
View directory record Official record
Conditions
Cannabis Dependence, Alcohol Dependence, Cannabis Use Disorder, Alcohol Use Disorder
Interventions
aprepitant, Placebo, Manual-guided behavioral counseling
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Sep 24, 2026, 9:32 AM EDT
Terminated Phase 2 Interventional Results available

Zonisamide for Heavy Drinkers With Bipolar Disorder

NCT01566370
View directory record Official record
Conditions
Alcohol Use Disorders, Bipolar Disorder
Interventions
Zonisamide, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Sep 24, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT

NCT01678196
View directory record Official record
Conditions
PTSD, Alcohol Abuse
Interventions
VA-CRAFT, Control
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Sep 24, 2026, 9:32 AM EDT