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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Abuse, Alcohol Dependence Clear all
Completed Phase 4 Interventional

Improving Hepatitis C Treatment in Injection Drug Users

NCT00148031
View directory record Official record
Conditions
Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
Interventions
Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment, Off-site HCV evaluation and treatment
Drug · Behavioral
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 65 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
2
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reactions to E-cigs and Alcohol

NCT03449017
View directory record Official record
Conditions
Alcohol Abuse, Nicotine Dependence Tobacco Product
Interventions
E-cig use
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Levetiracetam XR in Very Heavy Drinkers

NCT00970814
View directory record Official record
Conditions
Alcoholism
Interventions
BBCET, Levetiracetam XR, Sugar Pill
Behavioral · Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
5
States / cities
Baltimore, Maryland • Boston, Massachusetts • Lebanon, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2014 · Synced Jul 22, 2026, 3:58 PM EDT
Completed No phase listed Observational

Novel Real-world Methods in Social Drinkers and AUD

NCT05155176
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
Interventions
Intensive Day Monitoring
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse

NCT00220597
View directory record Official record
Conditions
Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior, Sexually Transmitted Diseases, Viral
Interventions
Trauma-focused group therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2013 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Results available

Telephone Coaching of Family Members of Veterans With Substance Abuse Problems

NCT03246646
View directory record Official record
Conditions
Substance Abuse
Interventions
Coaching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Gamified, Social Media Inspired Personalized Normative Feedback Alcohol Intervention for Sexual Minority Women

NCT03884478
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol; Harmful Use
Interventions
Personalized Normative Feedback
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
21 Years to 55 Years · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Intranasal Oxytocin and Social Cognition, Implicit Preferences and Craving in Alcohol Drinkers

NCT01829516
View directory record Official record
Conditions
AOD Use, Abuse, and Dependence
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Emeryville, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2016 · Synced Jul 22, 2026, 3:58 PM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Integration of (iSBIRT) for Teen Drug Use Into a Pediatric Network

NCT01454206
View directory record Official record
Conditions
Substance Use
Interventions
iSBIRT
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Jul 22, 2026, 3:58 PM EDT
Recruiting Phase 2 Interventional

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Interventions
Psilocybin, Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 4 Interventional Results available

Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy

NCT01087736
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcoholism
Interventions
Topiramate, Placebo administration
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 2 Interventional Results available

Varenicline Treatment of Alcohol Dependence in Smokers

NCT01553136
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse, Smoking, Alcohol Drinking
Interventions
Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 2 Interventional Results available

Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency

NCT00498628
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse
Interventions
Quetiapine fumarate, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
7
States / cities
Boston, Massachusetts • Lebanon, New Hampshire • Philadelphia, Pennsylvania + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Jul 22, 2026, 3:58 PM EDT
Not listed Not applicable Interventional

Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD

NCT01663337
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcohol Dependence
Interventions
Cognitive Processing Therapy (CPT), Relapse Prevention (RP)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional

Multimedia Toolkits to Implement 12-Step Recovery Concepts in Group Counseling

NCT02333357
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Multimedia 12-Step Toolkit, Treatment as Usual
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,483 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
11
States / cities
Camden, New Jersey • Brooklyn, New York • Eagleville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional

Project Health Link: Connecting Patients With Services

NCT00234221
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Strengths Based Case Management, Motivational Enhancement Therapy, Brief Informational Feedback
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 60 Years
Enrollment
686 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jul 22, 2026, 3:58 PM EDT
Completed No phase listed Observational

Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement

NCT00593034
View directory record Official record
Conditions
Substance-related Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 7, 2011 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

NCT02885311
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse, Alcohol Use Disorders
Interventions
Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone, Brief Advice, Referral to specialty substance use disorder treatment
Behavioral · Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth

NCT01442753
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking, Alcohol Drinking, Drug Abuse
Interventions
Family-Skills Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Substance Use Risk Education (SURE) Project

NCT00289965
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Drinking
Interventions
Counselor-administered Brief Motivational Intervention (BMI), Alcohol 101 Plus (interactive CD-ROM), AlcoholEdu (Internet-based tutorial)
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years to 25 Years
Enrollment
703 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jul 25, 2011 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Student Athlete Testing Using Random Notification

NCT00451854
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse, Substance Abuse
Interventions
Random, no advanced notice drug and alcohol testing
Procedure
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 19 Years
Enrollment
14,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 1 Interventional

Fecal Microbial Transplant for Alcohol Misuse in Cirrhosis

NCT03416751
View directory record Official record
Conditions
Cirrhosis, Alcohol Abuse
Interventions
Fecal Microbial Transplant, Placebo
Biological · Other
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Phase 2 Interventional Results available

Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ Persons

NCT01254877
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence
Interventions
Ondansetron, placebo ondansetron
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Jul 22, 2026, 3:58 PM EDT
Completed Not applicable Interventional Results available

Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women

NCT00127231
View directory record Official record
Conditions
HIV Infections, Alcoholism
Interventions
Brief alcohol intervention based on Project Treat, Standard care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Jul 22, 2026, 3:58 PM EDT